- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
- Blood transfusion and management
- Anesthesia and Pain Management
- Venous Thromboembolism Diagnosis and Management
- Bone health and osteoporosis research
- Bone fractures and treatments
- Diversity and Career in Medicine
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Shoulder Injury and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Pressure Ulcer Prevention and Management
- Innovations in Medical Education
- Bone and Joint Diseases
- Medical Education and Admissions
- Pelvic and Acetabular Injuries
- Anesthesia and Sedative Agents
- Opioid Use Disorder Treatment
- Osteoarthritis Treatment and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Patient-Provider Communication in Healthcare
- Surgical Simulation and Training
George Washington University
2023-2025
Johns Hopkins Medicine
2012-2023
Johns Hopkins University
2012-2023
Anderson Orthopaedic Research Institute
2022
Johns Hopkins Bayview Medical Center
2015-2021
ORCID
2020
Johns Hopkins Hospital
2019-2020
Michigan State University
2020
Oxford University Press (United Kingdom)
2020
Johns Hopkins University Applied Physics Laboratory
2019
Bacterial biofilm formation is a major complication of implantable medical devices that results in therapeutically challenging chronic infections, especially cases involving antibiotic-resistant bacteria. As an approach to prevent these electrospun composite coating comprised poly(lactic-coglycolic acid) (PLGA) nanofibers embedded poly(ε-caprolactone) (PCL) film was developed locally codeliver combinatorial antibiotics from the implant surface. The release each antibiotic could be adjusted...
Knee osteoarthritis (OA) is among the most common and disabling persistent pain conditions, with increasing prevalence impact around globe. In U.S., rising of knee OA has been paralleled by an increase in annual rates total arthroplasty (TKA), a surgical treatment option for late-stage OA. While TKA outcomes are generally good, post-operative trajectories functional status vary substantially; significant minority patients report ongoing impaired function following TKA. A number studies have...
Background: In April 2016, the U.S. Centers for Medicare & Medicaid Services initiated mandatory 90-day bundled payments total hip and knee arthroplasty much of country. Our goal was to determine duration care, charges, readmission rates by discharge disposition region after or arthroplasty. Methods: Using 2008 Provider Analysis Review database 100% sample, we identified patients who had undergone elective primary We collected data on patient age, sex, comorbidities, Census region,...
Dialysis-dependent patients can develop osteoarthritis or osteonecrosis, warranting hip knee arthroplasty. Their comorbidities predispose them to complications. Our goal was determine inpatient outcomes of dialysis-dependent after primary elective total arthroplasty.In the National Inpatient Sample, we identified 2934 who had undergone arthroplasty from 2000 through 2009 and compared with 6,186,475 same procedures were not dialysis-dependent. We described demographic characteristics,...
OBJECTIVES: To identify care settings associated with greater pressure ulcer risk in elderly patients hip fracture the postfracture period. DESIGN: Prospective cohort study. SETTING: Nine hospitals that participate Baltimore Hip Studies network and 105 postacute facilities to which from these were discharged. PARTICIPANTS: aged 65 older who underwent surgery for fracture. MEASUREMENTS: A full‐body skin examination was conducted at baseline (as soon as possible after hospital admission)...
Abstract Editor’s Perspective What We Already Know about This Topic Article Tells Us That Is New Background Although randomized trials show that patients do well when given less blood, there remains a persistent impression orthopedic surgery require higher hemoglobin transfusion threshold than other patient populations (8 g/dl vs. 7 g/dl). The authors tested the hypothesis in implementation of blood management program encouraging results decreased use with no change clinical outcomes....
The medical treatment of periprosthetic joint infection (PJI) involves prolonged systemic antibiotic courses, often with suboptimal clinical outcomes including increased morbidity and health-care costs. Oral intravenous monotherapies combination regimens were evaluated in a mouse model methicillin-resistant Staphylococcus aureus (MRSA) PJI.Oral linezolid or without oral rifampin, vancomycin daptomycin ceftaroline doxycycline, sham administered at human-exposure doses for 6 weeks PJI....
Abstract Background Letters of recommendation are considered one the most important factors for whether an applicant is selected interview orthopaedic surgery residency programs. Language differences in letters describing men versus women candidates may create differential perceptions by gender. Given gender imbalance surgery, we sought to determine there language Questions/purposes (1) Are word count and categories applicants, regardless author gender? (2) Is associated with category...
Our goal was to determine whether postoperative delirium is associated with inpatient complication rates after primary elective total hip arthroplasty (THA).Using the National Inpatient Sample, we analyzed records of patients who underwent THA from 2000 through 2009 identify (n = 13,551) and without 1,992,971) assess major perioperative complications (acute renal failure, death, myocardial infarction, pneumonia, pulmonary embolism, stroke) minor (deep vein thrombosis, dislocation, general...
To compare 1-year revision rates among left-sided and right-sided intertrochanteric femur fractures.
Osteoporosis has been described as a "silent epidemic." We describe an osteoporosis consultation program to facilitate the evaluation and treatment of inpatients with fragility fractures.The inpatient orthopaedic team voluntarily requested on all patients fracture. The consultant evaluated for secondary causes started calcium, vitamin D, bisphosphonates unless contraindicated. From November 2001 December 2003, fifty-three consultations were performed. A retrospective review charts hip...
Hip fracture is a serious injury for older adults, usually requiring surgical repair and extensive therapy. Informal caregivers can help adults make successful recovery by encouraging them to adhere the therapy plans improve their health behaviors. Few resources, however, are available these learn about how assist care receivers cope with unique caregiving situations.The study aims were develop comprehensive theory-based online hip resource center (OHRC) caregivers, Caring Caregivers,...
To identify care-related factors associated with hospital-acquired pressure ulcers (HAPUs).Prospective cohort study.Nine hospitals in Baltimore Hip Studies network.Six hundred fifty-eight individuals aged 65 and older who underwent surgery for hip fracture.Skin examinations at baseline on alternating days until hospital discharge. Participants were deemed to have a HAPU if they developed one or more new Stage 2 higher (PUs) during the stay.Longer emergency department stays lower incidence...
Bacterial biofilm infections of implantable medical devices decrease the effectiveness antibiotics, creating difficult-to-treat chronic infections. Prosthetic joint (PJI) are particularly problematic because they require prolonged antibiotic courses and reoperations to remove replace infected prostheses. Current models study PJI focus on Gram-positive bacteria, but Gram-negative (GN-PJI) increasingly common often more difficult treat, with worse clinical outcomes. Herein, we sought develop a...