Sahil Chaudhary
A5079683005- Lymphoma Diagnosis and Treatment
- PARP inhibition in cancer therapy
- COVID-19 Clinical Research Studies
- Cellular transport and secretion
- Immune Cell Function and Interaction
- Extracellular vesicles in disease
- Cell death mechanisms and regulation
- SARS-CoV-2 and COVID-19 Research
- T-cell and Retrovirus Studies
- MicroRNA in disease regulation
- CAR-T cell therapy research
- RNA regulation and disease
Virginia Commonwealth University
2024
University of Virginia Health System
2024
University of Wisconsin–Madison
2021-2022
Abstract Extracellular vesicle (EV) secretion is an important mechanism used by cells to release biomolecules. A common necroptosis effector—mixed lineage kinase domain like (MLKL)—was recently found participate in the biogenesis of small and large EVs independent its function necroptosis. The objective current study gain mechanistic insights into EV during Assessing number nanoparticle tracking analysis revealed increased released To evaluate nature such vesicles, we performed a newly...
Risk stratification of COVID-19 patients is essential for pandemic management. Changes in the cell fitness marker, hFwe-Lose, can precede host immune response to infection, potentially making such a biomarker an earlier triage tool. Here, we evaluate whether hFwe-Lose gene expression outperform conventional methods predicting outcomes (e.g., death and hospitalization) patients. We performed post-mortem examination infected lung tissue deceased determine hFwe-Lose's biological role acute...