Melissa Pergakis

ORCID: 0000-0003-4526-4176
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About
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Research Areas
  • Traumatic Brain Injury Research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cardiac Arrest and Resuscitation
  • Psychosomatic Disorders and Their Treatments
  • Acute Ischemic Stroke Management
  • Simulation-Based Education in Healthcare
  • Stroke Rehabilitation and Recovery
  • Surgical Simulation and Training
  • Functional Brain Connectivity Studies
  • Radiation Dose and Imaging
  • Neurosurgical Procedures and Complications
  • Health, Environment, Cognitive Aging
  • Neurological and metabolic disorders
  • Epilepsy research and treatment
  • Mobile Health and mHealth Applications
  • Cerebrovascular and Carotid Artery Diseases
  • Anatomy and Medical Technology
  • Telemedicine and Telehealth Implementation
  • Clinical Reasoning and Diagnostic Skills
  • Pharmacological Effects and Toxicity Studies
  • Advanced X-ray and CT Imaging
  • Clinical practice guidelines implementation
  • Anesthesia and Sedative Agents
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Autoimmune Neurological Disorders and Treatments

University of Maryland, Baltimore
2019-2025

University of Maryland Medical Center
2022-2025

Presbyterian Hospital
2024

New York Hospital Queens
2024

Columbia University
2024

NewYork–Presbyterian Hospital
2024

Hackensack Meridian Health
2023

Jersey Shore University Medical Center
2023

Emory University
2023

University of Pittsburgh
2023

Megan E. Barra Elizabeth Zink Thomas P. Bleck Eder Cáceres Salia Farrokh and 95 more Brandon Foreman Emilio Cediel J. Claude Hemphill Masao Nagayama DaiWai M. Olson José I. Suárez Venkatesh Aiyagari Yama Akbari Fawaz Al‐Mufti Sheila Alexander Anne W. Alexandrov Ayham Alkhachroum Moshagan Amiri Brian Appavu Meron Awraris Gebre Mary Kay Bader Neeraj Badjiata Ram Balu Rachel Beekman Ettore Beghi Kathleen R. Bell Erta Beqiri Tracey Berlin Yelena G. Bodien Varina L. Boerwinkle Mélanie Boly Alexandra Bonnel Emery N. Brown Elizabeth Carroll Sherry Chou Giuseppe Citerio Jan Classen Chad Condie Katie Cosmas Claire J. Creutzfeldt Neha Dangayach Michael DeGeorgia Caroline Der-Nigoghoss Masoom Desai Michael N. Diringer James Dullaway Brian L. Edlow Ari Ercole Anna Estraneo Guido J. Falcone Llewellyn Padayachy Soojin Park Melissa Pergakis Len Polizzotto Nader Pouratian Marilyn Price Spivack Lara Prisco J. Javier Provencio Louis Puybasset Lindsay Rasmussen Verena Rass Risa Richardson Cassia Righy Shinots Chiara Robba Courtney Robertson Benjamin Rohaut John D. Rolston Mario Rosanova Eric S. Rosenthal Mary E. Russell Gisele Sampaio Silva Leandro Sanz Simone Sarasso Aarti Sarwal Nicolas Schiff Caroline Schnakers David B. Seder V Shah Amy Shapiro-Rosen Angela Hays Shapshak Kartavya Sharma Tarek Sharshar Lori Shutter Jacobo Sitt Beth S. Slomine Peter Smielewski Wade S. Smith Emmanuel A. Stamatakis Alexis Steinberg Simona Ferioli Davinia Fernandez-Esp Ericka L. Fink Joseph J. Fins Jennifer Frontera Rishi Ganesan Ahmeneh Ghavam Joseph T. Giacino Christie Gibbons Emily J. Gilmore Olivia Gosseries

10.1007/s12028-023-01803-4 article EN Neurocritical Care 2023-08-23

Advances in adult learning theory and instructional technologies provide opportunities to improve neurology knowledge acquisition. This scoping review aimed survey the emerging landscape of educational innovation clinical neurology. With assistance a research librarian, we conducted literature search on November 4, 2021, using following databases: PubMed, Embase, Scopus, Cochrane Library, Education Resources Information Center, PsycINFO. We included studies innovative teaching methods for...

10.1212/ne9.0000000000200048 article EN cc-by Neurology Education 2023-03-01

<h3>Background and Objectives</h3> Delays in treatment of both herpes simplex virus (HSV) encephalitis seizures are associated with poor patient outcomes, but many physicians fail to recognize HSV despite classic presenting symptoms. Our goal was assess trainee performance a simulation-based case as the underlying etiology refractory status epilepticus. <h3>Methods</h3> This is prospective, observational, single-center study participants ranging from subinterns attending managing viral...

10.1212/ne9.0000000000200020 article EN cc-by Neurology Education 2022-11-17

Multidisciplinary acute stroke teams improve ischemic management but may hinder trainees' education, which in turn contribute to poorer outcomes community hospitals on graduation. Our goal was assess graduate neurology trainee performance independently of a multidisciplinary team the stroke, tissue plasminogen activator (tPA)-related hemorrhage, and cerebral herniation syndrome.In this prospective, observational, single-center simulation-based study, participants (subinterns attending...

10.1212/wnl.0000000000012972 article EN Neurology 2021-10-27
Martin M. Monti Rachel Beekman Norman M. Spivak Aurore Thibaut Caroline Schnakers and 95 more John Whyte Erika Molteni Venkatesh Aiyagari Yama Akbari Fawaz Al‐Mufti Sheila Alexander Anne W. Alexandrov Ayham Alkhachroum Moshagan Amiri Brian Appavu Meron Awraris Gebre Mary Kay Bader Neeraj Badjiata Ram Balu Megan E. Barra Ettore Beghi Kathleen R. Bell Erta Beqiri Tracey Berlin Thomas P. Bleck Yelena G. Bodien Varina L. Boerwinkle Mélanie Boly Alexandra Bonnel Emery N. Brown Eder Cáceres Elizabeth Carroll Emilio Cediel Sherry Chou Giuseppe Citerio Jan Classen Chad Condie Katie Cosmas Claire J. Creutzfeldt Neha Dangayach Michael DeGeorgia Caroline Der-Nigoghoss Masoom Desai Michael N. Diringer James Dullaway Brian L. Edlow Ari Ercole Anna Estraneo Guido J. Falcone Llewellyn Padayachy Soojin Park Melissa Pergakis Len Polizzotto Nader Pouratian Marilyn Price Spivack Lara Prisco J. Javier Provencio Louis Puybasset Lindsay Rasmussen Verena Rass Risa Richardson Cassia Righy Shinots Chiara Robba Courtney Robertson Benjamin Rohaut John D. Rolston Mario Rosanova Eric S. Rosenthal Mary E. Russell Gisele Sampaio Silva Leandro Sanz Simone Sarasso Aarti Sarwal Nicolas Schiff David B. Seder V Shah Amy Shapiro-Rosen Angela Hays Shapshak Kartavya Sharma Tarek Sharshar Lori Shutter Jacobo Sitt Beth S. Slomine Peter Smielewski Wade S. Smith Emmanuel A. Stamatakis Alexis Steinberg Salia Farrokh Simona Ferioli Davinia Fernandez-Esp Ericka L. Fink Joseph J. Fins Brandon Foreman Jennifer Frontera Rishi Ganesan Ahmeneh Ghavam Joseph T. Giacino Christie Gibbons Emily J. Gilmore Olivia Gosseries

10.1007/s12028-023-01873-4 article EN Neurocritical Care 2023-11-29

To assess trainees' performance in managing a patient with post-cardiac arrest complicated by status epilepticus.In this prospective, observational, single-center simulation-based study, trainees ranging from sub interns to critical care fellows evaluated and managed post cardiac patient, epilepticus. Critical action items were developed modified Delphi approach based on American Heart Association guidelines the Neurocritical Care Society's Emergency Neurological Life Support protocols. The...

10.1016/j.resplu.2022.100233 article EN cc-by-nc-nd Resuscitation Plus 2022-04-28

Introduction Evidence for optimal analgesia following subarachnoid hemorrhage (SAH) is limited. Steroid therapy pain refractory to standard regimens common despite lack of evidence its efficacy. We sought determine if steroids reduced or utilization other analgesics when given headache SAH. Methods performed a retrospective within-subjects cohort study SAH patients who received headache. compared daily scores, total opioid, and acetaminophen doses before, during, after steroids. Repeated...

10.1177/19418744231172350 article EN The Neurohospitalist 2023-04-28

Simulation bootcamps are used to onboard neurology trainees. It is not known whether these result in competency for acute ischemic stroke (AIS).

10.1212/ne9.0000000000200071 article EN cc-by Neurology Education 2023-05-26

Ischemia affecting two thirds of the MCA territory predicts development malignant cerebral edema. However, early infarcts are hard to diagnose on conventional head CT. We hypothesize that high-energy (190keV) virtual monochromatic images (VMI) from dual-energy CT (DECT) imaging enables earlier detection secondary injury edema (MCE).

10.21203/rs.3.rs-3508427/v1 preprint EN cc-by Research Square (Research Square) 2023-11-10

Abstract Objectives To assess the feasibility of a hybrid simulation-based workshop at national meeting for interventional neurology trainees focused on management acute ischemic stroke and tissue-plasminogen activator (tPA)-related hemorrhage. Methods In this prospective, observational, study fellows’ conference, participants were asked to manage patient with in neurointerventional suite followed by thrombolytic-related hemorrhage leading cerebral herniation during mechanical thrombectomy....

10.1101/2024.03.25.24304877 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2024-03-26

Endotracheal intubation, frequently required during management of refractory status epilepticus (RSE), can be facilitated by anesthetic medications; however, their effectiveness for RSE control is unknown. We performed a single-center retrospective review patients admitted to neurocritical care unit (NCCU) who underwent in-hospital intubation management. Patients intubated with propofol, ketamine, or benzodiazepines, termed anti-seizure induction (ASI), were compared received etomidate (EI)....

10.1016/j.ebr.2024.100645 article EN cc-by-nc-nd Epilepsy & Behavior Reports 2024-01-01

<title>Abstract</title> Background and Objectives Smartphone use in medicine is nearly universal despite a dearth of research assessing utility clinical performance. We sought to identify define smartphone during simulated neuro-emergencies. Methods In this retrospective review prospective, observational, single-center simulation-based study, participants, ranging from sub-interns attending physicians stratified by training level (novice, intermediate, advanced) managed variety neurological...

10.21203/rs.3.rs-3914951/v1 preprint EN cc-by Research Square (Research Square) 2024-02-06

Accurate classification of disorders consciousness (DoC) is key in developing rehabilitation plans after brain injury. The Coma Recovery Scale-Revised (CRS-R) a sensitive measure validated the phase care. We tested feasibility, safety, and impact CRS-R-guided ICU for patients with DoC acute hemorrhagic stroke.

10.1097/cce.0000000000001101 article EN cc-by-nc-nd Critical Care Explorations 2024-06-24

BACKGROUND Mechanical thrombectomy is the standard of care in acute ischemic stroke with anterior large vessel occlusion presenting within 6 hours symptom onset, but complications do exist. We assessed feasibility a hybrid simulation‐based workshop at national meeting for interventional neurology trainees focused on management and tissue‐plasminogen activator‐related hemorrhage. METHODS In this prospective, observational, study fellows’ conference, participants were asked to manage patient...

10.1161/svin.124.001416 article EN cc-by-nc-nd Stroke Vascular and Interventional Neurology 2024-09-04

Introduction: Cerebral edema is a common complication of multiple neurological diseases and strong predictor outcome, especially in traumatic brain injury large hemispheric infarction.Areas Covered: Traditional current treatments cerebral include treatment with osmotherapy or decompressive craniectomy at the time clinical deterioration. The authors discuss preclinical models variety disease states that have identified receptors, ion transporters, channels involved development as well...

10.1080/14656566.2021.1876663 article EN Expert Opinion on Pharmacotherapy 2021-01-20

This study assessed lifetime histories of discrete spiritual experiences recalled by 144 octogenarian men studied since adolescence and 80 spouses. Women were more likely to report experiences, as those from higher socioeconomic backgrounds judged open experience young adults. Factor analysis revealed four types related beauty/nature, negative life events, protection a sacred other, traditional religious settings. Men better childhood environments commonly reported concerning events. Those...

10.1080/15528031003698004 article EN Journal of Religion Spirituality & Aging 2010-06-23
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