Crîngu Antoniu Ionescu

ORCID: 0000-0003-4533-6766
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About
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Research Areas
  • Prenatal Screening and Diagnostics
  • Pregnancy and preeclampsia studies
  • Gynecological conditions and treatments
  • Uterine Myomas and Treatments
  • Endometriosis Research and Treatment
  • Ovarian cancer diagnosis and treatment
  • Maternal and fetal healthcare
  • Ovarian function and disorders
  • Congenital Diaphragmatic Hernia Studies
  • Congenital Anomalies and Fetal Surgery
  • Ectopic Pregnancy Diagnosis and Management
  • Maternal and Perinatal Health Interventions
  • Reproductive Biology and Fertility
  • Fetal and Pediatric Neurological Disorders
  • Reproductive Health and Contraception
  • Pregnancy-related medical research
  • Congenital Heart Disease Studies
  • Assisted Reproductive Technology and Twin Pregnancy
  • Urological Disorders and Treatments
  • Cleft Lip and Palate Research
  • Sexual function and dysfunction studies
  • Maternal Mental Health During Pregnancy and Postpartum
  • Cancer Risks and Factors
  • Hedgehog Signaling Pathway Studies
  • Preterm Birth and Chorioamnionitis

Clinical Emergency Hospital Bucharest
2013-2024

Carol Davila University of Medicine and Pharmacy
2015-2024

Yahoo (United Kingdom)
2019

Alexandria University
2018

University of Bari Aldo Moro
2017

Victor Babeș University of Medicine and Pharmacy Timișoara
2016

B cells are increasingly recognized as major players in multiple sclerosis pathogenesis. The BAFF/APRIL system is crucial for cell homoeostasis and may drive cell-dependent autoimmunity. We asked whether this affected by Interferon (IFN)-β therapy. analysed transcription of the ligands (BAFF, APRIL, TWE-PRIL) corresponding receptors (BAFF-R, TACI BCMA) TaqMan-PCR ex vivo whole blood immune subsets purified from IFN-β-treated patients. Serum BAFF concentrations were determined ELISA. This...

10.1093/brain/awn077 article EN Brain 2008-05-12

Couple infertility is a pathology with an absolute number of cases growing markedly over the last decade in connection mainly increased age couples wishing to conceive. Platelet‑rich plasma (PRP) alternative treatment used for several years experimental purposes. Yet, this method not yet defined as standard therapeutic option protocol poor responders assisted human reproduction procedures. Thus, present study retrospective conducted between February 2019 and 2020 evaluate effect ovarian PRP...

10.3892/etm.2021.10848 article EN Experimental and Therapeutic Medicine 2021-10-07

Ovarian masses are one of the most frequently identified entities in gynecological practice. Early differential diagnosis is a key factor medical management each patient. Transvaginal ultrasound along with additional preoperative testing, such as serum cancer antigen 125 (CA-125) levels and Risk Malignancy Algorithm (ROMA) score, usually provide sufficient information for presumptive diagnosis. Minimally invasive surgery therapeutic approach standard procedure uncomplicated benign adnexal...

10.1097/md.0000000000011762 article EN cc-by-nc Medicine 2018-08-01

Defensive caesarean section (CS) has become one of the most common medical procedure worldwide. Additionally, performing CS in accordance with patient's choice is an appropriate professional practice.This paper reports a prospective, observational, multicenter study to quantify use this type practice that performed by obstetricians avoid medico-legal complaints and decrease frequency malpractice litigations.We interviewed 73 from three distinct units obstetrics gynaecology, assess their...

10.1111/jep.13025 article EN cc-by Journal of Evaluation in Clinical Practice 2018-09-04

Romania has the highest incidence of cervical cancer morbidity and mortality in Europe. This study identifies major clusters for genital cancers, observes features cancer, determines extent to which is a contributor total Disability-Adjusted Life Year (DALY). Spatial analysis used Besag Newell’s method distribution, prevalence considered Arad County patients records (2008–2017), DALY was determined according WHO methodology GLOBOCAN 2013 data. Diagnosis established by histopathological...

10.3390/jcm8010096 article EN Journal of Clinical Medicine 2019-01-15

The extent of pregnancy in adolescents and young adults, especially low middle-income countries, is a source increasing concern given its social economic impact.We hypothesized that there would be correlations between female patients becoming pregnant at age practices such as harmful alcohol misuse, cigarette smoking, drug use, the use toxic substances, educational attainment, an essential absence health care seeking about outcome adolescent pregnancies.We performed prospective...

10.1111/jep.13036 article EN Journal of Evaluation in Clinical Practice 2018-10-17

Abstract The primary objective was to assess the utility of routine 3-dimensional (3D) ultrasound in evaluation infertile women and estimate prevalence uterine anomalies before use assisted reproductive technology (ART), using European Society Human Reproduction Embryology for Gynaecological Endoscopy classification system. A second effect on pregnancy rate patients who underwent techniques. We retrospectively studied 668 treated Department Obstetrics Gynecology Neonatology “Sf Ioan”...

10.1097/md.0000000000012764 article EN cc-by-nc Medicine 2018-10-01

Abstract Rationale, aims, and objectives The aim of this study was to focus attention on episiotomy practice in Romanian maternity units order identify factors associated with the very high rate procedure Romania consider strategies reduce it. Methods In clustered cross‐sectional study, a total 11 863 patients were recorded eight assess prevalence episiotomy. A random effects Poisson model used estimate univariate multivariate models. Results Among included for analysis, 8475 (71.4%) had an...

10.1111/jep.13062 article EN cc-by Journal of Evaluation in Clinical Practice 2018-11-13

Abstract Rationale, aims, and objectives It is estimated that 25% of pregnancies worldwide end in induced abortion. In Romania, the abortion situation shows a specific pattern. Following fall communist regime, first‐trimester abortions were legalized, between 1990 1992, country's rate was highest world, with 182 per 1000 women reproductive age. However, there are currently no statistically reliable data, as some not reported. The purpose this study to identify main circumstances determine...

10.1111/jep.13250 article EN Journal of Evaluation in Clinical Practice 2019-07-31

In Romania, as anywhere in the world, postpartum depression is considered to be most frequent health problem period. Unfortunately, it will later explained, majority of cases, patients, their families and relatives (as well medical staff charge patient) treat its serious possible implications superficially. Therefore especially order precisely establish perception consequences a targeted population, but also evaluate indirectly level importance given by doctors other healthcare...

10.6092/2282-1619/mjcp-2413 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2020-04-01

Holoprosencephaly (HPE) is the most common brain malformation. A wide spectrum of anatomical variants are characterized by a lack midline separation cerebral hemispheres. The aim this study was to assess ultrasound diagnostic criteria for HPE.A database 175 fetuses with central nervous system anomalies identified collected retrospectively from 2006 2016 in multicenter, retrospective, observational study. Among them 18 cases (10.2%) HPE were identified.The prevalence 2.5:10.000 sex...

10.11152/mu-1614 article EN Medical Ultrasonography 2019-02-12

Intrapartum hypoxia can lead to perinatal asphyxia, acidosis, neuronal injury, long-term morbidity or even death. asphyxia and be predicated by fetal acidosis. Umbilical cord gases are used evaluate a newborn�s acid-base status the presence of hypoxia. Depending on what references used, normal values for umbilical wildly vary. Although most papers set pH threshold [7.2 acidosis / acidemia, some studies suggest that neonatal mortality is increased only when below cut-off value 7.0. We did...

10.37358/rc.19.2.6965 article EN cc-by Revista de Chimie 2019-03-15

In the early differential diagnosis of endometrial cancer (EC), decisive and mandatory histological aspects are considered, in addition to obvious clinical manifestations. addition, sonographic characteristic relation stage, degree, types identified cancer. This bi-center retrospective observational study included 594 women with abnormal uterine bleeding outside pregnancy, for which a biopsy was performed Obstetrics Gynecology Departments Emergency County Hospitals Arad Timis Counties,...

10.3390/diagnostics11081342 article EN Diagnostics 2021-07-26

Submucosal fibroid location and size are predictive factors of impaired fertility. fibroids cause infertility through several mechanisms including distortion the endometrial cavity, increased uterine contractility, local inflammation remodeling blood supply. This is a monocentric, retrospective, cross-sectional study, conducted in Department Obstetrics Gynecology 'Sf. Pantelimon' Clinical Emergency Hospital, analyzing patients from 5-year period (January 2015-December 2019). In present...

10.3892/etm.2021.10917 article EN Experimental and Therapeutic Medicine 2021-10-25

Romania is a country with high rates of adolescent births, associating scarce comprehensive obstetrical management this specific population. This research aims to assess soft tissue trauma after vaginal birth in teenage mothers compared their adult counterparts. A retrospective case-control study was conducted for one year two hospitals. All deliveries were considered; the age cut-off value considered at 20 years old case and control groups. Lacerations divided into three subgroups,...

10.3390/ijerph182111491 article EN International Journal of Environmental Research and Public Health 2021-10-31
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