A5057140572- Congenital Diaphragmatic Hernia Studies
- Congenital Heart Disease Studies
- Tracheal and airway disorders
- Acute Kidney Injury Research
- Hernia repair and management
- Pulmonary Hypertension Research and Treatments
- Neonatal Respiratory Health Research
- Tumors and Oncological Cases
- Central Venous Catheters and Hemodialysis
- Mechanical Circulatory Support Devices
- Healthcare professionals’ stress and burnout
- Vascular Malformations and Hemangiomas
- Endometrial and Cervical Cancer Treatments
- Ultrasound in Clinical Applications
- Pregnancy and preeclampsia studies
- Esophageal and GI Pathology
- Dialysis and Renal Disease Management
- Endometriosis Research and Treatment
- Gastrointestinal disorders and treatments
- Infective Endocarditis Diagnosis and Management
- Congenital Anomalies and Fetal Surgery
- Vascular anomalies and interventions
- Urological Disorders and Treatments
- Asthma and respiratory diseases
- Maternal Mental Health During Pregnancy and Postpartum
Carol Davila University of Medicine and Pharmacy
2016-2024
Spitalului Clinic de Urgență pentru Copii Maria Sklodowska Curie
2013-2024
Spitalul Clinic de Urgență pentru Copii Cluj-Napoca
2021
The purpose of this study was to identify the predictors burnout in healthcare workers during COVID-19 pandemic. Data were collected from March June 2020, pandemic, employees two Romanian hospitals. Five hundred and twenty-three completed a series questionnaires that measured burnout, job demands, resources, personal resources. Among respondents, 14.5% had clinical level exhaustion (the central component burnout). Three demands (work–family conflict, lack preparedness/scope practice,...
Dysmenorrhea is defined as the presence of painful menstruation, and it affects daily activities in different ways. The aims this study were to assess prevalence management dysmenorrhea determine impact on quality life medical students. conducted was prospective, analytical observational performed between 7 November 2019 30 January 2020 five university centers from Romania. data collected using an original questionnaire regarding menstrual cycles dysmenorrhea. information about relationships...
Glaucoma, one of the significant causes blindness worldwide, is a chronic optic neuropathy, characterized by progressive loss retinal ganglion cells and specific perimetric defects. This study aimed to assess association between risk glaucoma progression different systemic vascular abnormalities. A 4-year prospective was carried out on 204 patients diagnosed with open-angle glaucoma. Associated pathology documented in 102 cases. Progression encountered 57 (55.9%) comorbidities only 10 (9.8%)...
Cardiac arrhythmias are a frequent complication in the evolution of patients with congenital heart disease. Corrective surgery for these malformations is an additional predisposition to appearance arrhythmias. Several factors related patient, as well therapeutic management, involved etiopathogenesis cardiac occurring post-operatively. The risk immediate postoperative period correlated patient's young age and low weight at surgery. change geometry, hemodynamic stress, post-surgical scars...
Lipoblastoma (LB) and lipoblastomatosis (LBS) are uncommon benign mesenchymal tumors of embryonal fat, occurring almost exclusively in infancy early childhood. These fast‑growing have an excellent prognosis if properly treated. Eight consecutive children having pathologically demonstrated LB treated by the same surgical team were retrospectively reviewed. There 5 boys 3 girls between 7 to 36 months (median age 22 months). The localization was on thigh (1 case), abdomen (2 cases), axillary...
Background: Neonates have an increased risk of vitamin D insufficiency due to the inadequate supplementation mothers and infants after birth. Insufficiency is frequently detected in critically ill patients associated with disease severity mortality. There yet be a consensus on appropriate regimen D3 high-risk infants. Aim: The main objectives this study were determine prevalence neonates severe comorbidities evaluate whether high-dose oral administration leads normal plasmatic concentrations...
Cytokine adsorber (CytoSorb) has been used successfully as adjunctive treatment for adult patients with elevated cytokine levels in the setting severe sepsis and septic shock to reduce blood myoglobin, unconjugated bilirubin, conjugated bilirubin. In this article we present case of a nine-month-old male infant who was admitted NICU due after cardiac surgery, Fallot tetralogy, multisystem organ failure (MSOF) including liver renal which treated by combination continuous hemodiafiltration...
One of the main markers arterial stiffness is pulse wave velocity (PWV). This parameter well studied as a marker for end-organ damage in adult population, being considered strong predictor major cardiovascular events. study assessed PWV children with chronic kidney disease (CKD) risk. We conducted prospective observational single-center cohort 42 consecutively pediatric patients (9-18 years old) terminal CKD and dialysis, at Hemodialysis Department "M. S. Curie" Hospital, Bucharest. measured...
The main goal of surgical treatment for gastroschisis and omphalocele is the reduction viscera in abdominal cavity closure abdomen, but challenge to succeed without detrimental effects increased intraabdominal pressure. In this regard, we performed a retrospective study all patients admitted Neonatal Intensive Care Unit 'Marie Sklodowska Curie' Emergency Clinical Hospital Children, from January 2011 until June 2021. Our aim was highlight presence postoperative compartment syndrome. We...
Congenital heart disease (CHD) remains a predisposing cardiac condition for infective endocarditis (IE). Case report: We present the case of 8-year-old boy with no known pre-existing diagnosed (IE) Gemella sanguinis. After admission, he underwent transthoracic echocardiography (TTE), which revealed presence Shone syndrome bicuspid valve, mitral parachute valve and severe aortic coarctation. He developed paravalvular abscess regurgitation left ventricle (LV) systolic dysfunction required...
Acute kidney injury occurs commonly in the Neonatal Intensive Care Unit and is associated with increased mortality morbidity. We report a case of neonate congenital heart disease who developed acute after cardiac surgery, administration iodinated contrast media for catheterization, combination nephrotoxic drugs.A term without prenatal diagnosis good postnatal transition was transferred at 13 days life to MS Curie Emergency Hospital Children, Newborn Unit, from regional hospital where he...
In Romania, as anywhere in the world, postpartum depression is considered to be most frequent health problem period. Unfortunately, it will later explained, majority of cases, patients, their families and relatives (as well medical staff charge patient) treat its serious possible implications superficially. Therefore especially order precisely establish perception consequences a targeted population, but also evaluate indirectly level importance given by doctors other healthcare...
We present a series of four newborns diagnosed with complicated congenital vascular anomalies, different localization: Congenital lymphatic malformation (CLM) on the left hemithorax extending upper limb; hepatic hemangioma (CHH) important complications in first 7 weeks life; Kaposiform hemangioendothelioma (KHE) lower limb Kasabach Merritt phenomenon (KMM) and most probable diffuse capillary overgrowth (DCMO). All patients were treated combined antiproliferative therapy sirolimus...
Background and Objectives: This retrospective study aimed to identify the main comorbidities found in gynecological patients hospitalized for endometrial lesions analyze relationships between these each type of lesion. The Charlson comorbidity index (CCI) was calculated, thus assessing patient’s probability survival relation underlying disease existing comorbidities. Materials Methods: During 2015–2019, 594 cases vaginal bleeding outside pregnancy were included research. For all cases,...
Cardiac fibroblasts play a main role in the physiological turnover of extracellular matrix, as well its pathological remodeling. A study was performed on batch 23 cases who died various cardiac complications secondary to scarring myocardial infarctions. The aim assess fibroblast involvement repair under ischemic conditions after infarction. Tissue samples from left ventricle were taken these for microscopy examination, order investigate type and degree fibrosis presence interstitial...
The outbreak of COVID-19 can be associated with cardiac and pulmonary involvement is emerging as one the most significant life-threatening complications in patients kidney failure receiving hemodialysis. Here, we report a critically ill case 13-year-old female patient acute pericarditis bilateral pleurisy, screened positive for SARS-CoV-2 RT-PCR, presented high fever, frequent dry cough, dyspnea tachypnea. COVID-19-induced myopericarditis has been noted to complication concomitant...
The present study presents the experience gained in Newborn Intensive Care Unit (NICU) of 'Maria S. Curie' Emergency Clinical Hospital for Children Bucharest (Romania) after performing a series bedside surgery interventions on newborns with congenital diaphragmatic hernia (CDH). We conducted retrospective analysis data all patients operated on-site between 2011 and 2020, terms pre- post-operative stability, procedures performed, complications outcomes. An control group was used to provide...
Brain abscesses are a possible complication of bacterial sepsis or central nervous system infection but uncommon in the neonatal period. Gram-negative organisms often cause them, Serratia marcescens is an unusual and meningitis this age group. This pathogen opportunistic frequently responsible for nosocomial infections. Despite existing antibiotics modern radiological tools, mortality morbidity remain significant group patients. We report unilocular brain abscess preterm neonate caused by...
(1) Background: Transposition of the great arteries (TGA) is most common congenital heart disease, accounting for 5-7% all cardiac anomalies, with a prevalence 0.2-0.3 per 1000 live births. (2) Aim: Our main objectives were to evaluate clinical safety balloon atrial septostomy in neonates and possible complications. Furthermore, we tried establish whether procedure should be performed TGA patients small septal defects, regardless oxygen saturation, within center where corrective surgery...
MTHFR polymorphism has been inconsistently linked to thrombotic events-some studies have shown its contribution venous thrombosis, arterial and ischemic stroke, whereas others found no statistically significant correlation between them. A descriptive case series study was performed in the Neonatal Intensive Care Unit of "Marie Sklodowska Curie" Emergency Clinical Hospital for Children Bucharest, Romania. All patients had positive results variants; 14 were compound heterozygosity, 13 C677T...
The rareness of H‑type tracheoesophageal fistula in conjunction with its unspecific clinical presentation and wide range anatomical makes diagnosis treatment a problematic topic for both ear, nose throat (ENT) specialists pediatric surgeons worldwide. Symptoms signs H‑TOF are easily misleading. Diagnostic methods, most the times, dependent on physician's experience; therefore, various errors may be made. We analyzed our experience managing cases over last 15 years. Advice strategies action...
Asthma is the most common chronic disease affecting children, with a negative impact on their quality of life. often associated comorbid allergic diseases, and its severity may be modulated by immunoglobulin E (IgE)-mediated allergen sensitization. Omalizumab humanized monoclonal anti-IgE antibody, first biological therapy approved to treat patients aged ≥6 years severe asthma. The primary objective our study was investigate efficacy safety in Romanian children asthma.In this observational...