Catalin-Gabriel Smarandache

ORCID: 0000-0002-0126-0926
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About
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Research Areas
  • Esophageal and GI Pathology
  • Gastric Cancer Management and Outcomes
  • Colorectal Cancer Screening and Detection
  • Metastasis and carcinoma case studies
  • Esophageal Cancer Research and Treatment
  • Amoebic Infections and Treatments
  • Gastrointestinal disorders and treatments
  • Pancreatitis Pathology and Treatment
  • Orthopedic Surgery and Rehabilitation
  • Trauma and Emergency Care Studies
  • Tracheal and airway disorders
  • Pancreatic and Hepatic Oncology Research
  • Clinical Nutrition and Gastroenterology
  • Abdominal Trauma and Injuries
  • Elbow and Forearm Trauma Treatment
  • Dysphagia Assessment and Management
  • Genetic and Kidney Cyst Diseases
  • Climate Change and Health Impacts
  • Biofield Effects and Biophysics
  • Gastroesophageal reflux and treatments
  • Health and Wellbeing Research
  • Antibiotic Resistance in Bacteria
  • Parasitic infections in humans and animals
  • Cholinesterase and Neurodegenerative Diseases
  • Electromagnetic Fields and Biological Effects

Clinical Emergency Hospital Bucharest
2016-2024

Bucharest Emergency University Hospital
2024

Carol Davila University of Medicine and Pharmacy
2011-2022

Background As global rates of mortality decrease, non-fatal injury have increased, particularly in low Socio-demographic Index (SDI) nations. We hypothesised this pattern would be demonstrated regard to bony hand and wrist trauma over the 27-year study period. Methods The Global Burden Diseases, Injuries, Risk Factors Study 2017 was used estimate prevalence, age-standardised incidence years lived with disability for 195 countries from 1990 2017. Individual injuries included fractures, thumb...

10.1136/injuryprev-2019-043495 article EN cc-by Injury Prevention 2020-03-13

Introduction. With more than 1,000,000 infections around the world, SARS-Cov 2 is responsible for most severe healthcare crisis in last 100 years. Aim. The paper analyzes impact of COVID 19 pandemic upon current ophthalmological clinical activity. Materials and Method. A comparative analyses was carried regarding activity March 2019 2020: number one day hospitalizations, continuous percentage emergencies, surgeries, bed turn over, mean hospital stay. protocols health care personnel...

10.4323/rjlm.2020.96 article EN Romanian Journal of Legal Medicine 2020-03-15

The present study aimed to compare the clinical, paraclinical, intraoperative findings, and postoperative complications in acute cholecystitis diabetic patients vs. non‑diabetic patients. A 2‑year retrospective was performed on who underwent emergency cholecystectomy for between 2017 2019 at 4th Department of Surgery, Emergency University Hospital Bucharest. subgroup numbered 46 eligible one 287 Demographics, severity clinical forms, biological variables (including white cell count, urea,...

10.3892/etm.2021.10190 article EN Experimental and Therapeutic Medicine 2021-05-13

Gastrointestinal stromal tumors (GISTs) are the most common malignant mesenchymal lesions of gastrointestinal tract. They originate from interstitial cells Cajal and characterized by overexpression tyrosine kinase receptor, protein product c‑KIT gene (KIT). In this retrospective study, conducted over a period 10 years, we retrieved our database, total number 57 patients, admitted operated in surgical department 'Sf. Pantelimon' Emergency Clinical Hospital, Bucharest, for digestive tumors,...

10.3892/etm.2021.10497 article EN Experimental and Therapeutic Medicine 2021-07-27

Neuroendocrine renal carcinoma represents less than 1% of all primary neoplasia the kidney. Most frequently poorly differentiated is diagnosed in advanced stages and they have an aggressive evolution limited survival rate. carcinomas that arise from pelvis are associated with squamous cell or adenocarcinoma.

10.4183/aeb.2016.355 article EN Acta Endocrinologica (Bucharest) 2016-01-01

Hepatocellular carcinoma is one of the primary liver malignancies responsible for over a million deaths per year worldwide (approximately 10% all in adult age range). The diagnosis HCC can be difficult and often requires use more than microscopic technique. A retrospective study was performed on batch 42 cases that died due to metastasis or other secondary complications. Tissue samples were taken order investigate tumour antigenic constellation by means IHC method using large variety...

10.3892/etm.2021.9701 article EN Experimental and Therapeutic Medicine 2021-01-25

The prevalence of diabetic foot complications is continuously increasing as diabetes has become one the most important "epidemics" our time. main objective this study was to describe appropriate surgical intervention for complicated neuropathic foot; secondary goal find risk factors associated with minor/major amputation and good or adverse outcomes. This an observational, retrospective conducted between 1 January 2018 31 December 2019, which included 251 patients from General Surgery...

10.3390/life12081156 article EN cc-by Life 2022-07-29

Cardiac fibroblasts play a main role in the physio­logical turnover of extracellular matrix, as well its pathological remodeling. A study was performed on batch 23 cases who died various cardiac complications secondary to scarring myocardial infarctions. The aim assess fibroblast involvement repair under ischemic conditions after infarction. Tissue samples from left ventricle were taken these for microscopy examination, order investigate type and degree fibrosis presence interstitial...

10.3892/etm.2021.9700 article EN Experimental and Therapeutic Medicine 2021-01-25

BACKGROUND We analyzed the outcomes of early biliary decompression by a minimally invasive approach in acute pancreatitis (ABP). MATERIAL AND METHODS A retrospective study was conducted on 143 patients with ABP who underwent laparoscopic or endoscopic between January 2015 and March 2022. Data from observation sheets surgical protocols were terms demographic characteristics, clinical paraclinical features at admission, comorbidities, therapeutic management, outcomes. RESULTS The mean patient...

10.12659/msm.937016 article EN Medical Science Monitor 2022-06-21

Multimodal treatment of breast cancer has made steady progress in recent years. The involvement modern oncology, diagnostic imaging techniques and surgical treatment, have brought a definite benefit to patients, defining the multidisciplinary cancer. introduction immunohistochemical testing genetic screening led prioritization therapy according their results correct approach initiating treatment. main aim present study was conduct comparative analysis through retrospective therapeutic means...

10.3892/etm.2021.10979 article EN Experimental and Therapeutic Medicine 2021-11-17

Romania is located in an area with high seismicity, the role of emergency hospitals being a major one providing medical aid case earthquakes mass casualties.The article aims to characterize particular issues related specific pathology seismic disaster, whose proactive awareness and anticipation are important for good management medical-surgical activity.An extensive review literature was conducted, including scientific studies, recommendations, practice guides on response planning, published...

10.37897/rmj.2018.1.5 article EN cc-by Romanian Medical Journal 2018-03-31

Degenerative neurological diseases (senile dementia, Alzheimer`s disease, glaucoma), post-stroke sequelae are increasing as prevalence nowadays, in context of aging general population, and there strong evidences that astrocytes may play a significant role neuroprotection. The study evaluates the effects low intensity frequency electromagnetic field (EMF) �in vitro� stimulation (195 mA, 7-8 Hz) on glial cells, different conditions, order to identify neuroprotective potential. Three cell lines...

10.37358/rc.20.2.7933 article EN Revista de Chimie 2020-03-03
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