A5042816038- Anesthesia and Pain Management
- Nausea and vomiting management
- Spine and Intervertebral Disc Pathology
- Peripheral Nerve Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Shoulder Injury and Treatment
- Anesthesia and Sedative Agents
- Hemodynamic Monitoring and Therapy
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Abdominal Trauma and Injuries
- Dental Anxiety and Anesthesia Techniques
- Tracheal and airway disorders
- Clinical practice guidelines implementation
- Pain Mechanisms and Treatments
- Central Venous Catheters and Hemodialysis
- Ultrasound in Clinical Applications
- Venous Thromboembolism Diagnosis and Management
- Airway Management and Intubation Techniques
- Trauma and Emergency Care Studies
- Nerve Injury and Rehabilitation
University of Copenhagen
2014-2024
Gentofte Hospital
2024
Copenhagen Academy for Medical Education and Simulation
2024
Copenhagen University Hospital
2016-2024
Rigshospitalet
2023-2024
Amager Hospital
2024
Hvidovre Hospital
2024
Nordsjællands Hospital
2014-2022
We have developed a peripheral nerve catheter, attached to needle, which works like an adjustable suture. used in-plane ultrasound guidance place 45 catheters close the femoral, saphenous, sciatic and distal tibial nerves in cadaver legs. displaced after their initial placement then attempted return them original positions. evaluate secondary catheter placements spread of injectate around nerves. In 10 cases, we confirmed position by magnetic resonance imaging. judged 43/45 successful 42/43...
Summary The volume‐duration relationship using low concentrations of ropivacaine for peripheral nerve blocks is unknown, even though are increasingly used clinically. We investigated the effect 0.2% on common peroneal block duration. With ethical committee approval, 60 consenting, healthy volunteers were randomly allocated to receive one five volumes (2.5, 5.0, 10, 15 or 20 ml) administered by ultrasound‐guided, catheter‐based injection (at 10 ml.min −1 ) near nerve. Our primary outcome was...
The effect of local anaesthetic concentration on peripheral nerve block duration is unclear. Recent clinical trials found blocks equivalent despite changing but with a fixed dose. A criticism these studies that the doses used were above proposed dose-duration ceiling level, masking any potential different concentrations duration.We investigated using dose below level. We hypothesised would affect duration.Randomised, double-blind trial.Single-centre, academic hospital.Healthy volunteers.Each...
Background Existing techniques for placing and maintaining the position of peripheral nerve catheters are associated with variable success rates frequent secondary failures. These factors may affect clinical efficacy usefulness catheters. Methods We developed a new concept prototype ultrasound‐guided in‐plane positioning readjustment (patent pending). The integrated catheter–needle comprises three parts: curved needle, catheter clear echogenic markings attached to needle tail detachable hub...
Background Sciatic nerve blocks are used for many orthopaedic procedures on the knee, lower leg, foot and ankle. However, as block durations vary considerably, timing of supplemental analgesia is challenging. Therefore, knowledge effect local anaesthetic (LA) dose duration important to outweigh benefits increasing LA against risk systemic toxicity. In this randomized, double‐blind trial, we aimed explore relationship between volume ropivacaine 0.2% sciatic duration. We hypothesized that...
Summary We performed a randomised double‐blind pilot study in 16 healthy volunteers to investigate the success rate for placing new suture‐method catheter sciatic nerve block. A was inserted into both legs of and each randomly allocated receive 15 ml lidocaine 2% through one leg saline other leg. Successful placement defined as 20% decrease maximum voluntary isometric contraction dorsiflexion ankle. Secondary outcomes were plantar flexion at ankle, surface electromyography cold sensation....
Background and objectives Characteristics of a nerve block depend on the distribution local anesthetic (LA) close to nerve. The relationship between longitudinal LA characteristics has not been investigated in viv o , but one vitro study showed decrements action potential amplitudes with increasing exposure length. We describe influence neural duration adjusted for other likely influential factors. Methods analyzed data from an ethical board approved prospective consecutive collected dataset...
The speed of local anesthetic (LA) injections in peripheral regional anesthesia ranges from slow continuous infusions (3-12 mL/h) to rapid manual (>7500 mL/h). Optimizing injection could augment the spread LA toward targeted nerves and influence nerve block characteristics. objective this study was investigate whether a single dose affects duration.After approval Danish Regional Scientific Ethics Committee, we enrolled 60 healthy adult volunteers. We used an ultrasound-guided catheter-based...
Introduction Ultrasound-guided peripheral venous catheter placement (UG-PVCP) is a key skill for establishing intravenous access, especially in patients with anatomical challenges. Ultrasound highly operator-dependent, and it essential to ensure sufficient level of competence when educating healthcare professionals. Competence can be acquired through simulation-based training (SBT) using phantoms or simulators. We developed phantom SBT, this study, we explore the phantom's usability...
Background The reported variation in nerve block duration is considerable. To individualize therapy, knowledge of the intra‐ vs inter‐individual variability essential. We investigated relative contribution these 2 parameters to overall variability. Methods With ethics committee approval, we conducted a randomized cross‐over trial where 20 healthy volunteers received 8 common peroneal blockades with lidocaine 0.5% on 4 consecutive days. Allocations were 5 mL either right or left side and 10...
A shoulder block without lung affection is desirable. In this study, we compared a low versus high volume of modified supraclavicular brachial plexus block. We hypothesised that local anaesthetic would provide non-inferior success rate with better preserved function.Healthy volunteers were randomised to receive ultrasound guided 5 or 20 ml ropivacaine 0.5% at the departure suprascapular nerve from plexus. Primary outcome was successful block-defined as cutaneous sensory axillary and motor...
Trials comparing programmed, intermittent boluses (PIB) and continuous infusion in catheter-based nerve blocks found no analgesic differences. However, as these trials used equal doses of local anesthetic (LA), the time action each bolus was not accounted for. Therefore, dose-sparing benefits PIB may have been overlooked. We compared effect administered intervals resembling with infusion. hypothesized that provided non-inferior analgesia despite consuming less LA.Eighty-one patients...