A5027408871- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Tracheal and airway disorders
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Nausea and vomiting management
- Respiratory Support and Mechanisms
- Health Systems, Economic Evaluations, Quality of Life
- Meta-analysis and systematic reviews
- Delphi Technique in Research
- Statistical Methods in Clinical Trials
- Orthopedic Surgery and Rehabilitation
- Spine and Intervertebral Disc Pathology
- Pain Management and Opioid Use
- Peripheral Nerve Disorders
- Elbow and Forearm Trauma Treatment
- Total Knee Arthroplasty Outcomes
- Nerve Injury and Rehabilitation
- Orthopaedic implants and arthroplasty
- Ultrasound in Clinical Applications
- Hemodynamic Monitoring and Therapy
- Vascular anomalies and interventions
- Voice and Speech Disorders
- Opioid Use Disorder Treatment
- Enhanced Recovery After Surgery
Zealand University Hospital
2017-2025
Copenhagen University Hospital
2013-2025
Zealand University Hospital Køge
2022-2025
University of Copenhagen
2022-2025
Nordsjællands Hospital
2013-2024
Rigshospitalet
2014-2022
Capital Region of Denmark
2016-2022
Aarhus University Hospital
2016
Summary Both the American Society of Anesthesiologists and UK NAP 4 project recommend that an unspecified pre‐operative airway assessment be made. However, choice is ultimately at discretion individual anaesthesiologist. We retrieved a cohort 188 064 cases from Danish Anaesthesia Database, investigated diagnostic accuracy anaesthesiologists’ predictions difficult tracheal intubation mask ventilation. Of 3391 intubations, 3154 (93%) were unanticipated. When was anticipated, 229 929 (25%) had...
Abstract Objective To investigate the effects of one and two doses intravenous dexamethasone in patients after total knee arthroplasty. Design Randomised, blinded, placebo controlled trial with follow-up at 90 days. Setting Five Danish hospitals, September 2018 to March 2020. Participants 485 adult participants undergoing Intervention A computer generated randomised sequence stratified for site was used allocate three groups: DX1 (dexamethasone (24 mg)+placebo); DX2 mg)+dexamethasone mg));...
Introduction Methodological studies (ie, that evaluate the design, conduct, analysis or reporting of other in health research) address various facets research including, for instance, data collection techniques, differences approaches to analyses, quality, adherence guidelines publication bias. As a result, methodological can help identify knowledge gaps methodology and strategies improvement practices. Differences study names lack guidance contribute comparability across difficulties...
We compared implementation of systematic airway assessment with existing practice on prediction difficult mask ventilation. Twenty-six departments were cluster-randomised to assess eleven risk factors for management (intervention) or continue their (control). In both groups, patients predicted as a ventilation and/or intubation registered in the Danish Anaesthesia Database, notational summary management. The trial's primary outcome was respective incidence unpredicted and easy two groups....
When analysing and presenting results of randomised clinical trials, trialists rarely report if or how underlying statistical assumptions were validated. To avoid data-driven biased trial results, it should be common practice to prospectively describe the assessments assumptions. In existing literature, there is no consensus on assess for analyses trials. With this study, we developed suggestions test validate behind logistic regression, linear Cox regression when Two investigators compiled...
Abstract Background The impact of demographic‐ and surgical factors on individual perioperative opioid requirements is not fully understood. Anaesthesia personnel adjust administrations based their own clinical experience, expert opinions local guidelines. This survey aimed to assess the current practice anaesthesia regarding intraoperative treatment for postoperative analgesia rescue dosing strategies in post‐anaesthesia care unit Denmark. Methods We conducted a cross‐sectional online with...
Indications for using supraglottic airway devices have widened over time and they now hold a prominent role in guidelines difficult management. We aimed to describe the use of included adult patients undergoing general anaesthesia registered Danish Anaesthesia Database from 2008 2012 whose management had been recorded as difficult, defined as: ≥ 3 tracheal intubation attempts; failed intubation; or facemask ventilation. In Database, separate module requires technique used each successive...
Summary Facemask ventilation is an essential part of airway management. Correctly predicting difficulties in facemask may reduce the risk morbidity and mortality among patients at risk. We aimed to develop evaluate a weighted score for difficult during anaesthesia. analysed cohort 46,804 adult who were assessed pre‐operatively 13 predictors management subsequently underwent general developed Difficult ( DIFFMASK ) two consecutive steps: first, multivariate regression analysis was performed;...
In order to ensure the validity of results randomised clinical trials and under some circumstances optimise statistical power, most methods require validation underlying assumptions. The present paper describes how trialists in major medical journals report tests assumptions when analysing trials. We also consider possible solutions improve current practice by adequate reporting conclude that there is a need reach consensus on which should be assessed, these assessed what done if are violated.
Background Both dexamethasone and dexmedetomidine increase the duration of analgesia peripheral nerve blocks. The authors hypothesized that combined intravenous would result in a greater when compared with alone placebo. Methods randomly allocated participants undergoing surgery foot or ankle under general anesthesia popliteal (sciatic) saphenous block to combination 12 mg 1 µg/kg dexmedetomidine, dexamethasone, placebo (saline). primary outcome was measured as time from performance until...
Pre-operative airway assessment in Denmark is based on a non-specific clinical assessment. Systematic, evidence-based and consistent may reduce the incidence of unanticipated difficult management. By assessing multiple predictors for management, predictive value increases. The Simplified Airway Risk Index (SARI) multivariate risk score predicting intubation. This study aims to compare use SARI with non-specified Further, examination registration mask ventilation prediction ventilation. We...
The European Society of Anesthesiology and Intensive Care recommends the use neuromuscular blocking agents (NMBA) in adults, to facilitate tracheal intubation reduce its associated complications. Children who undergo may suffer some same complications, however, no consensus exists regarding NMBA for pediatric population. We will explore existing evidence assessing effects avoidance versus facilitation children infants.
Evidence in perioperative care is insufficient. There an urgent need for large research programmes, including pragmatic randomised trials, testing daily clinical treatments and unanswered question, thereby providing solid evidence effects of interventions given to a growing number patients undergoing surgery anaesthesia. This may be achieved through collaborations. Collaboration Evidence-based Practice Research Anaesthesia (CEPRA) novel collaborative network founded pursue evidence-based...
Summary The effects of oral dexamethasone on peripheral nerve blocks have not been investigated. We randomly allocated adults scheduled for forearm or hand surgery to placebo (n = 61), 12 mg 61) 24 58) about 45 min before lateral infraclavicular block. Mean (SD) time until first pain after block were: 818 (219) min; 1171 (318) and 1256 (395) min, respectively. (98.3%CI) differences in postoperative vs. 437 (280–594) p < 0.001; 85 (‐78 249) 0.21, difference was 354 (218–490) 0.001. Both...