A5020478633- Soil Moisture and Remote Sensing
- Cryospheric studies and observations
- Climate change and permafrost
- Plant Water Relations and Carbon Dynamics
- Earthquake Detection and Analysis
- Liver Disease Diagnosis and Treatment
- RNA modifications and cancer
- interferon and immune responses
- Precipitation Measurement and Analysis
- Soil and Unsaturated Flow
- Telomeres, Telomerase, and Senescence
- Ionosphere and magnetosphere dynamics
- earthquake and tectonic studies
- Hepatitis B Virus Studies
- Cancer-related molecular mechanisms research
- Arctic and Antarctic ice dynamics
- Cytokine Signaling Pathways and Interactions
- Hydrology and Watershed Management Studies
- Lung Cancer Treatments and Mutations
- Hepatitis C virus research
- Environmental and Agricultural Sciences
- Traditional Chinese Medicine Studies
- Liver Diseases and Immunity
- Molecular Biology Techniques and Applications
- Seismic Waves and Analysis
Nanjing Medical University
2015-2025
Chinese Academy of Sciences
2016-2025
Jiangsu Province Hospital
2014-2025
Tianjin Medical University Cancer Institute and Hospital
2015-2025
Shanghai Institute of Materia Medica
2022-2025
Huazhong University of Science and Technology
2023-2025
Tongji Hospital
2023-2025
National Clinical Research Center for Digestive Diseases
2017-2025
University of Florida
2025
Xi'an Jiaotong University
2014-2025
Available treatments for hepatitis B e antigen (HBeAg)-negative chronic are associated with poor sustained responses. As a result, nucleoside and nucleotide analogues typically continued indefinitely, strategy the risk of resistance unknown long-term safety implications.We compared efficacy peginterferon alfa-2a (180 microg once weekly) plus placebo, lamivudine (100 mg daily), alone in 177, 179, 181 patients HBeAg-negative B, respectively. Patients were treated 48 weeks followed an...
A major research plan entitled “Integrated on the ecohydrological process of Heihe River Basin” was launched by National Natural Science Foundation China in 2010. One key aims this is to establish a platform that integrates observation, data management, and model simulation foster twenty-first-century watershed science China. Based diverse needs interdisciplinary studies within plan, program called Watershed Allied Telemetry Experimental Research (HiWATER) implemented. The overall objective...
Abstract In this study, we report on the spatial and temporal distribution of seasonal snow depth derived from passive microwave satellite remote-sensing data (e.g. SMMR 1978 to 1987 SMM/ I 2006) in China. We first modified Chang algorithm then validated it using meteorological observation data, considering influences vegetation, wet snow, precipitation, cold desert frozen ground. Furthermore, is dynamically adjusted based variation grain size density. Snow-depth indirectly by MODIS...
The Watershed Allied Telemetry Experimental Research (WATER) is a simultaneous airborne, satellite‐borne, and ground‐based remote sensing experiment aiming to improve the observability, understanding, predictability of hydrological related ecological processes at catchment scale. WATER consists cold region, forest, arid region experiments as well hydrometeorology took place in Heihe River Basin, typical inland river basin northwest China. field campaigns have been completed, with an...
Core Ideas Heihe was the first basin-scale integrated observatory network established in China. An intensive flux observation matrix experiment conducted. New techniques, e.g., wireless sensor network, matrix, and airborne remote sensing, are used. The is useful land surface processes research. Research on at catchment scale has drawn much attention over past few decades, a number of watershed observatories have been worldwide. River Basin (HRB), which contains second largest inland river...
ABSTRACT Many permafrost maps in China have been compiled since the early 1960s. The scales of these range from local (1:600 000) to regional scale (1:10 000 000). classification systems differ among maps. indices for used mapping projects include spatial continuity (areal extent) and thickness permafrost, air ground temperatures ‐ice content. All those data retrieved, digitised published Environmental Ecological Science Data Center West China. These represent best understanding at time...
Increased fructose consumption predisposes the liver to nonalcoholic fatty disease (NAFLD), but mechanisms are elusive. Thioredoxin-interacting protein (TXNIP) links oxidative stress NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome activation and this signaling axis may be involved in fructose-induced NAFLD. Here, we explore role of reactive oxygen species (ROS)-induced TXNIP overexpression fructose-mediated hepatic NLRP3 activation, inflammation, lipid...
Abstract. The alpine region is important in riverine and watershed ecosystems as a contributor of freshwater, providing stimulating specific habitats for biodiversity. In parallel, recent climate change, human activities other perturbations may disturb hydrological processes eco-functions, creating the need next-generation observational modeling approaches to advance predictive understanding such region. However, several formidable challenges, including cold harsh climate, high altitude...
In a trial of patients with hepatitis B e antigen (HBeAg)-negative chronic B, 24 week post-treatment biochemical and virological response rates peginterferon alpha-2a or without lamivudine were significantly higher than alone. The effect pre-treatment factors on responses was investigated.Multivariate analyses performed using available data from 518 treated lamivudine, A defined as alanine aminotransferase (ALT) normalisation virus (HBV) DNA level <20,000 copies/ml.In logistic regression...
Abstract We introduce a multiscale dataset obtained from Heihe Watershed Allied Telemetry Experimental Research (HiWATER) in an oasis-desert area 2012. Upscaling of eco-hydrological processes on heterogeneous surface is grand challenge. Progress this field hindered by the poor availability observations. HiWATER experiment designed to address challenge through instrumentation hierarchically nested scales obtain and multidisciplinary data. The observation system consists flux matrix eddy...
This letter introduces the ecohydrological wireless sensor network (EHWSN), which we have installed in middle reach of Heihe River Basin. The EHWSN has two primary objectives: first objective is to capture multiscale spatial variations and temporal dynamics soil moisture, temperature, land surface temperature heterogeneous farmland; second provide a remote-sensing ground-truth estimate with an approximate kilometer pixel scale using upscaling. ground truth can be used for validation...
The soil freeze–thaw controls the hydrological and carbon cycling thus affects water energy exchanges at land surface. This article reported a newly developed algorithm for distinguishing freeze/thaw status of surface soil. was based on information from Advanced Microwave Scanning Radiometer Enhanced (AMSR-E) which records brightness temperature (Tb) in afternoon after midnight. criteria discriminant functions were obtained both radiometer observations model simulations. First all, microwave...
Purslane (Portulaca oleracea L.) is a fleshy herbaceous plant. So far, little information available on the response of this plant to combined drought and heat stress. In study, changes in physiological metabolic levels were characterized after treatments with drought, stresses. Both individual stress increased malondialdehyde (MDA), electrolyte leakage (EL), O2•− activities superoxide dismutase (SOD), peroxidase (POD), while declined chlorophyll content. No significant differences found...
Abstract Global Positioning System (GPS) has been widely used to sense crustal deformation and ionospheric anomalies, particularly seismic disturbances. In March 2011, the earthquakes with magnitude of up Mw = 9 occurred in Tohoku near east coast Honshu, Japan. The GPS Earth Observation Network (GEONET) Japan more than 1200 continuously operating stations provides a unique opportunity study detailed this paper, pattern evolution disturbances following are investigated by dense GEONET data,...
Summary Several eukaryotic Heme‐associated proteins (HAPs) have been reported to bind specifically DNA fragments containing CCAAT ‐box; however, the physiological functions and direct targets of these HAP in plants remain unclear. In this study, we showed that At 5A as a transcription factor interacted with motif vivo , AtXTH21 one target 5A, was involved freezing stress resistance. The AtHAP5A overexpressing were more tolerant, whereas loss‐of‐function mutant sensitive than wild‐type...
Glutamine is an abundant and versatile nutrient in cancer cells. Head neck squamous cell carcinoma (HNSCC) was reported to be dependent on mainly glucose, not glutamine, for producing the energy required survival proliferation.The roles of ASCT2 (SLC1A5) associated glutamine metabolism were determined by MTT, colony formation, uptake, intracellular glutathione, ROS detection, immunofluorescence, immunohistochemistry, apoptosis enzyme-linked immunosorbent assays as well animal studies.We...