A5056939027- Visual perception and processing mechanisms
- Neural and Behavioral Psychology Studies
- Multisensory perception and integration
- Gaze Tracking and Assistive Technology
- Acute Kidney Injury Research
- EEG and Brain-Computer Interfaces
- Tactile and Sensory Interactions
- Sepsis Diagnosis and Treatment
- Heart Failure Treatment and Management
- Neural dynamics and brain function
- Chronic Kidney Disease and Diabetes
- Autopsy Techniques and Outcomes
- Machine Learning in Healthcare
- Memory and Neural Mechanisms
- Visual Attention and Saliency Detection
- Phonetics and Phonology Research
- Spatial Cognition and Navigation
- Potassium and Related Disorders
- Poisoning and overdose treatments
- Chronic Disease Management Strategies
- Cardiovascular Function and Risk Factors
- Death, Funerary Practices, and Mourning
- Face Recognition and Perception
- COVID-19 Clinical Research Studies
- Alcoholism and Thiamine Deficiency
Amsterdam University Medical Centers
2021-2025
University of Amsterdam
2022
Amsterdam UMC Location University of Amsterdam
2022
Utrecht University
2016-2020
Clinical Insights
2020
To facilitate visual continuity across eye movements, the system must presaccadically acquire information about future foveal image. Previous studies have indicated that working memory (VWM) affects saccade execution. However, reverse relation, effect of execution on VWM load is less clear. investigate causal link between and VWM, we combined a task task. Participants were instructed to remember one, two, or three shapes performed either No Saccade-, Single Saccade- Dual (corrective)...
Patients with neglect ignore or respond slower to contralesional stimuli. Neglect negatively influences independence in activities of daily living (ADL). Prism adaptation (PA) is one the most frequently studied treatments, yet there little evidence regarding positive effects on behavior ADL.To assess whether PA subacute phase ameliorates situations varying complexity.A total 70 patients admitted for inpatient stroke rehabilitation received either sham (SA) 2 weeks, full access standard...
Background: Improving prediction models to timely detect lung cancer is paramount. Our aim develop and validate for early detection of in primary care, based on free-text consultation notes, that exploit the order context among words sentences. Methods: Data all patients enlisted 49 general practices between 2002 2021 were assessed, we included those older than 30 years with at least one note. We developed two using a hierarchical architecture relies attention bidirectional long short-term...
The experience of our visual surroundings appears continuous, contradicting the erratic nature processing due to saccades. A possible way system can construct a continuous is by integrating presaccadic and postsaccadic input. However, saccades rarely land exactly at intended location. Feature integration would therefore need be robust against variations in saccade execution facilitate continuity. In current study, observers reported feature (color) target, which occasionally changed slightly...
One of the factors contributing to a seamless visual experience is object correspondence—that is, integration pre- and postsaccadic information into one representation. Previous research had suggested that before execution saccade, target loaded working memory subsequently used locate after saccade. Until now, studies on correspondence have not taken previous fixations account. In present study, we investigated influence previously fixated correspondence. To this end, adapted gaze correction...
Whenever we move our eyes, some visual information obtained before a saccade is combined with the after saccade. Interestingly, saccades rarely land exactly on target, which may pose problem for transsaccadic perception as it could affect quality of postsaccadic input. Recently, however, showed that feature integration actually unaffected by deviations landing points. Possibly, remains because presaccadic shift attention follows intended target and not actual point during regular saccades....
In this experiment, we demonstrate modulation of the pupillary light response by spatial working memory (SWM). The has previously been shown to reflect focus covert attention, as demonstrated smaller pupil sizes when a subject covertly attends location on bright background compared dark background. We took advantage measure attention during SWM delay. Subjects performed two tasks in which stimulus was presented periphery either or half black and white display. Importantly, subjects had...
The retinal location of visual information changes each time we move our eyes. Although it is now known that remapped in retinotopic coordinates across eye-movements (saccades), currently unclear how head-centered auditory saccades. Keeping track the a sound source requires rapid multi-modal reference frame transformation when making To reveal this transformation, designed an experiment where participants attended or cue and executed saccade. After saccade had landed, target could be...
To assess, validate and compare the predictive performance of models for in-hospital mortality COVID-19 patients admitted to intensive care unit (ICU) over two different waves infections. Our were built with high-granular Electronic Health Records (EHR) data versus less-granular registry data. Observational study all 19 Dutch ICUs participating in both national quality National Intensive Care Evaluation (NICE) EHR-based Data Warehouse (hereafter EHR). Multiple developed on from first 24 h...
Acute kidney injury (AKI) is an abrupt decrease of function which common in the intensive care. Many AKI prediction models have been proposed, but analysis what added value clinical notes and medical terminologies has not yet conducted. We developed internally validated a model to predict that includes only variables, also terminologies. Our results were overall good (AUROC > 0.80). The best used variables 0.899).
In oculomotor selection, each saccade is thought to be automatically biased toward uninspected locations, inhibiting the inefficient behavior of repeatedly refixating same objects. This automatic bias related inhibition return (IOR). Although IOR seems an appealing property that increases efficiency in visual search, such a mechanism would not efficient other tasks. Indeed, evidence for additional, more flexible control over refixations has been provided. Here, we investigated whether task...
A limited amount of visual information is retained between saccades, which subsequently stored into a memory system, such as transsaccadic memory. Since the capacity limited, selection crucial. Selection relevant modulated by attentional processes presaccadic shift attention. This involuntary attention occurs prior to execution saccade and leads acquisition at an intended target. The aim present study was investigate influence that another effect, inhibition return (IOR), has on gets IOR...
Introduction: Despite the interest in memory functioning Korsakoff’s syndrome (KS), visual working capacity KS is still poorly understood. Results from last decades on limitations appear to be mixed, clearly calling for further investigations.Method: We investigated storage of patients diagnosed with using a change detection paradigm. Nine and thirty age- education- matched healthy controls were presented twice 2, 3, 4, or 6 bars different orientations had detect whether orientation target...
Timely diagnosis of heart failure (HF) is essential to optimize treatment opportunities that improve symptoms, quality life, and survival. While most patients consult their general practitioner (GP) prior HF, the early stages HF may be difficult identify. An integrated clinical support tool aid in identifying at high risk HF. We therefore constructed a prediction model using routine health care data.Our study involved dynamic cohort (≥35 years) who consulted GP with either dyspnoea and/or...
Recent research demonstrated substantial heterogeneity in the Kidney Disease: Improving Global Outcomes (KDIGO) acute kidney injury (AKI) diagnosis and staging criteria implementations clinical research. Here we report an additional issue implementation of criteria: incorrect description application a stage 3 serum creatinine (SCr) criterion. Instead increase SCr to or beyond 4.0 mg/dL, studies apparently interpreted this criterion as by mg/dL.Using sample 8124 consecutive intensive care...
Saccade execution is quite inaccurate, leading to a frequent undershoot of saccades. To compensate for this inaccuracy, the intended target stored in working memory prior saccade. Object and spatial information are encoded separate storages. When eyes do not land accurately, visual search task performed guided by content. Research suggests corrective saccade could then be initiated towards target, contributing our perceived stability world. However, it still unknown if both object can...
Abstract Objectives Heart failure (HF) is a prevalent syndrome with considerable disease burden, healthcare utilization and costs. Timely diagnosis essential to improve outcomes. This study aimed compare the diagnostic performance of B-type natriuretic peptide (BNP) N-terminal proBNP (NT-proBNP) in detecting HF primary care. Our second aim was explore if personalized thresholds (using age, sex, or other readily available parameters) would further accuracy over universal thresholds. Methods A...
Our senses generally complement each other: whereas vision gives us an uncontested spatial resolution, audition allows for localization in 360 degrees. To promote unity between sensory systems, signals must be integrated into a multimodal coordinate system. Visual information is retinotopically encoded, and head-related auditory transformed retinotopic coordinates the superior colliculus. Because eyes frequently move, updating of with regards to retina crucial ability localize after saccade....