Coronavirus disease 2019 (COVID-19) has been recognized as a pandemic by the World Health Organization. Global efforts have exerted to prevent spreading of through political decisions together with personal behaviors, which depend on awareness public. The goal this study is assess knowledge, perceptions and attitude Egyptian public towards COVID-19 disease. We conducted cross-sectional survey about these points, was distributed among adult Egyptians. Five hundred fifty nine persons completed...

COVID-19 infection has been recognized as a pandemic by the World Health Organization. Efforts to prevent spread of disease are threatened appearance disease-associated social stigma in society. In Egypt, small wave directed at different groups started appear. Here we report features associated Egypt and suggest recommendations overcome this before it grows have physical psychological impacts on

Abstract Introduction ChatGPT, a recently released chatbot from OpenAI, has found applications in various aspects of life, including academic research. This study investigated the knowledge, perceptions, and attitudes researchers towards using ChatGPT other chatbots Methods A pre-designed, self-administered survey Google Forms was employed to conduct study. The questionnaire assessed participants’ knowledge chatbots, their awareness current artificial intelligence (AI) applications, its...

Objectives: COVID-19 has been recognized as a pandemic by the World Health Organization, and physicians are at frontline to confront disease. Burnout syndrome (BOS) is resulting from chronic workplace stress that not successfully managed. The objective of this study evaluate frequency associated risk factors BOS among sample Egyptian during pandemic. Methods: Using Maslach Inventory Human Services Survey, cross-sectional electronic survey was conducted assess target group. Results: Two...

COVID-19 is a multisystem disease, and some patients suffer from physical or psychological symptoms for weeks even months after infection, which described as post-COVID syndrome. The goal of this study evaluating the prevalence post-COVID-19 among Egyptian detecting factors associated with presence these symptoms.An on-line cross-sectional survey using Google Forms was used to conduct present study, took place between June August 2021.Three hundred ninety-six participants filled in survey....

Abstract Background ChatGPT, a chatbot launched by OpenAI in November 2022, has generated both excitement and concern within the healthcare education, research, practice communities. This study aimed to explore knowledge, perceptions, attitudes, practices of undergraduate medical students regarding use ChatGPT similar chatbots their academic work. Methods An anonymous, structured questionnaire was developed using Google Forms administered as part cross-sectional study. The survey targeted...

Biobanking is a relatively new concept in Egypt. Building good relationship with different stakeholders essential for the social sustainability of biobanks. To establish this relationship, it necessary to assess attitude groups towards concept. The objective work knowledge, attitude, and opinions Egyptian patients biobanking issues.We designed structured survey be administered coming outpatient clinics 3 university hospitals included questions estimating level knowledge about term "Biobank",...

In 2020, the World Health Organization has characterized COVID-19, a disease caused by infection with SARS-CoV-2 virus, as pandemic. Although few vaccines and drugs have been approved to, respectively, prevent or treat disease, several clinical trials are still ongoing to test new mitigate burden of Few studies shown role host genetics in prognosis drug response highlighting importance diverse participation COVID-19 trials. The goal this study is assess public attitudes Egypt, Saudi Arabia,...

Abstract Breast cancer, the most prevalent cancer among women, has posed a significant challenge in identifying biomarkers for early diagnosis and prognosis. This study aimed to elucidate gene expression profile of Estrogen Receptor-1 (ESR-1), long non-coding RNA HOTAIR, microRNA-130a serum Egyptian breast patients, evaluating potential HOTAIR miR-130a as predicting pathological parameters BC. The involved 45 patients with primary BC, samples collected preoperatively postoperatively twice....

Biobanking is a relatively new concept in the Arab region. Targeting different stakeholders to introduce of biobanking and develop an acceptance it among them important for growth Undergraduate students life sciences represent segment stakeholders, since they constitute potential future biobank customers. Limited funding, lack awareness existence term "biobanking" itself these students, questions regarding best marketing strategies presented challenges planning most effective message...

Abstract Background Biobanks have recently been established in several low- and middle-income countries (LMICs) the Arab region of Middle East. We aimed to explore views biobank managers regarding challenges, ethical issues, governance arrangements their biobanks. Methods In-depth semi-structured qualitative interviews were conducted with a purposive sample eight from Egypt (6), Jordan (1), Sudan (1). Interviews performed either face-to-face, by phone, or via Zoom lasted approximately 45–75...

Coronavirus disease 2019 (COVID-19) has affected millions of people worldwide. During the early stages vaccination in Egypt, ChAdOx1 nCoV-19 and BBIBP-CorV vaccines were most distributed. The aim this study was to compare immune responses short-term efficacies these two vaccines. We recruited adults who received doses either vaccine. Samples collected after first dose nCoV-1 second both Antibodies against SARS-CoV-2 antigens measured using LABScreen™ COVID Plus kits, cell-mediated assessed...

Population-based genomics studies have proven successful in identifying genetic variants associated with diseases. High-quality biospecimens linked informative health data from diverse segments of the population made such research possible. However, success biobank depends on willingness public to participate this type research. We aimed explore factors four low- and middle-income countries Arab region (Egypt, Jordan, Morocco, Sudan). used a previously validated questionnaire assess several...

Abstract Background Severe COVID-19 disease is typically associated with an urgent need for supplemental oxygen therapy that may be successfully delivered through conventional methods or require invasive mechanical ventilation. Early prediction of the ventilation could significantly improve outcomes patients. Plasma levels D-dimer and a number inflammatory markers as well values complete blood counts, all measured in first two days hospital admission patients, were evaluated their...

Abstract Background β-Thalassemias represent a group of genetic disorders caused by human hemoglobin beta ( HBB ) gene mutations. The radical curative approach is to correct the mutations causing disease. CRISPR-CAS9 novel gene-editing technology that can be used auspiciously for treatment these disorders. study aimed investigate utility modification hematopoietic stem cells in β-thalassemia with IVS-1-110 mutation. Methods and results We successfully isolated CD34 + from peripheral blood...

To enhance efforts against plagiarism, a deeper understanding of its various aspects is essential. This cross-sectional questionnaire study assessed the knowledge, attitudes, subjective norms, and self-reported plagiarism practices among health researchers in Egypt Lebanon. A validated was distributed to postgraduate students faculty members across 15 universities through personal emails researcher-specific social media platforms. Out 283 respondents, mean knowledge score 14.8 ± 3.7 out...

Objectives Collection and storage of biospecimens data for biobanking raise many ethical concerns. Stakeholders’ opinions about these issues are important since they can help in the development guidelines to govern activities. Physicians among stakeholders contact potential participants could be biobank users. The goal this study is evaluate perceptions attitude Egyptian physicians towards biobanking. Methods A cross-sectional online survey was designed distributed with target group between...

Background: Assessing the public perspectives regarding donation of biospecimens to biobanks would be helpful with establishment in Arab region. Objective: To develop a biobanking questionnaire Arabic and assess its psychometric properties. Design: Multicenter cross-sectional study. Methods: We used two-step process for development. First, we decided on important constructs followed by development an item pool through review scientific literature published questionnaires. The was refined...

Objectives: Chronic Obstructive Pulmonary Disease (COPD) is one of the most common pulmonary diseases. The concomitant association Sleep Apnea (OSA) and COPD known as Overlap Syndrome (OS). This study aimed to identify markers for predicting OS, among routine laboratory tests, including differential blood counts.Methods: One hundred twenty-five patients with exacerbated were enrolled in screened OSA using Epworth Sleepiness Scale (ESS). Those a positive ESS score underwent polysomnography...

Abstract Introduction Acute myeloid leukemia (AML) is the most common acute in adults. There growing evidence that microRNAs (miRNAs) provide prognostic information AML. MiR‐204 has a tumor suppressor function, and several studies have proven its role solid cancers. The aim of this work to evaluate level expression miR‐204 adults newly diagnosed with AML normal karyotype correlate disease outcome different factors. Patients methods study included 87 adult patients Detection was done using...

<ns3:p><ns3:bold>Background:</ns3:bold> The development of biobanks is associated with the emergence new ethical challenges. In Egypt, several have been established, but there are no specific local guidelines to guide their work. aim this study develop recommendations for Egyptian human biobanking guidelines, which take into consideration cultural and legal framework in Egypt.</ns3:p><ns3:p> <ns3:bold>Methods:</ns3:bold> We searched literature available guidelines. Six themes were concern...