A5023975112- Cellular Mechanics and Interactions
- Endodontics and Root Canal Treatments
- Dental Erosion and Treatment
- dental development and anomalies
- Antimicrobial Peptides and Activities
- Biochemical and Structural Characterization
- Dental Trauma and Treatments
- Oral microbiology and periodontitis research
- Nicotinic Acetylcholine Receptors Study
- Essential Oils and Antimicrobial Activity
- Oral and Maxillofacial Pathology
- Innovations in Medical Education
- Bone Tissue Engineering Materials
- Marine Sponges and Natural Products
- Clinical Reasoning and Diagnostic Skills
- Laser Applications in Dentistry and Medicine
- Bone and Dental Protein Studies
- Silk-based biomaterials and applications
- Pluripotent Stem Cells Research
- Tissue Engineering and Regenerative Medicine
- Empathy and Medical Education
- Dental materials and restorations
- Genomics and Chromatin Dynamics
- Microtubule and mitosis dynamics
Université de Strasbourg
2017-2023
Hôpitaux Universitaires de Strasbourg
2023
Biomatériaux et Bioingénierie
2018-2021
Inserm
2018-2020
Regenerative NanoMedicine
2020
Abstract The rise of antimicrobial resistant microorganisms constitutes an increasingly serious threat to global public health. As a consequence, the efficacy conventional antimicrobials is rapidly declining, threatening ability healthcare professionals cure common infections. Over last two decades host defense peptides have been identified as attractive source new antimicrobials. In present study, we characterized antibacterial and mechanistic properties D-Cateslytin (D-Ctl), epipeptide...
Abstract The excessive use of antifungal agents, compounded by the shortage new drugs being introduced into market, is causing accumulation multi-resistance phenotypes in many fungal strains. Consequently, alternative molecules to conventional agents are urgently needed prevent emergence resistance. In this context, Cateslytin (Ctl), a natural peptide derived from processing Chromogranin A, has already been described as an effective antimicrobial agent against several pathogens including...
Mechanical properties of the cellular environment are known to influence cell fate. Chromatin de-condensation appears as an early event in reprogramming. Whereas ratio euchromatin versus heterochromatin can be increased chemically, we report herein for first time that also by purely changing mechanical microenvironment successive 24 h-contact cells on a soft substrate alternated with relocation and growth 7 days hard substrate. An initial contact caused massive SW480 cancer death necrosis,...
Over the past decades, walking bleach technique using sodium perborate was considered a safe and effective method to nonvital discolored teeth. However, has been classified as carcinogenic, mutagenic, toxic for reproduction by European Union legislation. Its use is therefore prohibited since April 2015. The initially described inside/outside bleaching technique, combining internal external application of 10% carbamide peroxide, an alternative perborate. While good esthetic results low risks...
Invasive cervical resorption (ICR) is a dental lesion starting in the region and involving loss of hard tissue as result odontoclastic action. Due to its localization invasive pattern, this process represents challenging clinical situation. When feasible, major aim an ICR treatment completely remove pathologic (specifically at entry point lesion) seal resulting defect, without compromising tooth rehabilitation. In context, choosing how access resorptive lacuna essential. Two main options...
The success of endodontic treatments depends on the elimination intracanal pathogens. Since irrigation and instrumentation can only partially eliminate bacteria, use medicaments is suggested to improve eradication root canal Antimicrobial peptides derived from Chromogranin A display bacteriolytic activities are potentially excellent candidates be combined with conventional medicaments. In this study, we D-Cateslytin (D-Ctl), together calcium hydroxide (Ca(OH)2) test for enhanced...
The article A New Combination with D‑Cateslytin to Eradicate Root Canal Pathogens, written by Claire Ehlinger, Pauline Dartevelle, Abdurraouf Zaet, Yoshihito Kurashige, Youssef Haïkel, Marie‑Helene Metz‑Boutigue and Céline Marban was originally published electronically on the publisher's internet portal (currently SpringerLink) August 22, 2019 without open access.