A5066707563- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Total Knee Arthroplasty Outcomes
- Osteoarthritis Treatment and Mechanisms
- Orthopaedic implants and arthroplasty
- Inflammatory mediators and NSAID effects
- Cancer-related molecular mechanisms research
- Orthopedic Infections and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Head and Neck Cancer Studies
- Tissue Engineering and Regenerative Medicine
- Polysaccharides and Plant Cell Walls
- Advanced battery technologies research
- Circular RNAs in diseases
- Anesthesia and Pain Management
- MicroRNA in disease regulation
- Nausea and vomiting management
- Polysaccharides Composition and Applications
- Wound Healing and Treatments
- Heterotopic Ossification and Related Conditions
- Salivary Gland Tumors Diagnosis and Treatment
- Surgical Sutures and Adhesives
- Electrospun Nanofibers in Biomedical Applications
- Rheumatoid Arthritis Research and Therapies
Civil Aviation University of China
2024
Tianjin University of Science and Technology
2024
Shanxi Medical University
2024
Sun Yat-sen University
2024
458th Hospital PLA
2024
Jiangxi Provincial People's Hospital
2024
Central South University
2017-2023
Xiangya Hospital Central South University
2017-2023
First Affiliated Hospital of Jiangxi Medical College
2023
Nanchang University
2023
Abstract Reconstruction of complex cartilage defects has remained a great challenge for tissue engineering due to the lack stem cells and chronic inflammation within joint. In this study, we have developed an injectable pig cartilage-derived decellularized extracellular matrix (dECM) hydrogels repair defects, which shown sound biocompatibility immunomodulatory capacity both in vitro vivo. The dECM can enhance chondrogenic differentiation human urine-derived (USCs). As by experiment, USCs...
Nonmetallic functional species beyond the first coordination shell can affect or even dictate electrocatalytic performance of single-atom catalysts via indirect, long-range interaction with metal atoms.
Local recurrence after therapy remains a challenging problem for hypopharyngeal cancer due to the chemotherapy resistance. Metformin has been linked reduced risk and better diagnosis through promoting global DNA methylation in cells by controlling S-adenosylhomocysteine (SAHH) activity. However, mechanisms which metformin inhibits remain elusive. In this study, we aim investigate role of illustrate mechanism regulates long non-coding RNAs (lncRNAs) expression. CCK-8 annexin-V/PI double...
Abstract Background Osteoarthritis (OA) is a common skeletal system disease that has been partially attributed to genetic factors. The hand frequently affected, which seriously affects the patient’s quality of life. However, pathogenetic mechanism osteoarthritis (hand OA) still elusive. Methods A genome-wide association study (GWAS) summary OA was obtained from UK Biobank dataset, contains data total 452,264 White British individuals, including 37,782 patients. transcriptome-wide (TWAS)...
Anterior cervical corpectomy and fusion (ACCF) is an effective surgical technique for spondylotic myelopathy (CSM). However, no data exist regarding long-term outcomes after ACCF with the dynamic plate CSM. This study aimed to provide minimum 5-year clinical radiographic of anterior reconstruction using titanium mesh cage (TMC) Thirty-five patients who underwent single- or 2-level TMC treatment CSM were retrospectively investigated. The Japanese Orthopedic Association (JOA) score was used...
Osteoarthritis (OA) is a progressive cartilage degradation disease, concomitant with synovitis, osteophyte formation, and subchondral bone sclerosis. Over 37% of the elderly population affected by OA, number cases increasing as global ages. Therefore, objective this study was to identify analyze hub genes OA combining comprehensive bioinformatics analysis tools provide theoretical basis in further effective therapies. Two sample sets GSE46750 contained 12 pairs synovial membrane normal...
Cervical disc arthroplasty (CDA) has been considered as an alternative to cervical arthrodesis in the treatment of degenerative diseases (CDDD). The aim this study was assess long-term clinical and radiographic outcomes CDA with Prestige-LP Disc. A total 61 patients who underwent single- or two-level Disc were retrospectively investigated at a minimum 6-year follow-up. Clinical assessments included visual analogue scale (VAS) for neck arm pain, Neck Disability Index (NDI), Japanese...
Study Design. Retrospective analysis. Objective. To investigate the effect of width and depth inserted cervical disc prosthesis on heterotopic ossification (HO) after arthroplasty, to explore relationship between clinical outcome HO. Summary Background Data. The mechanism HO formation still remains unknown. Footprint mismatch was common in arthroplasty. Compared with endplate, some prostheses were smaller length. Methods. Retrospectively analyze patients who underwent arthroplasty...
Hypopharyngeal cancer has relatively high incidence rates in China, especially high-risk areas. However, data on the role of major risk factors these areas China are still limited.We have evaluated roles alcohol, tobacco and betel quid consumption, oral health, based 278 hypopharyngeal cases 693 controls from two centers Central South China. The odds ratio (OR) 95% confidence interval (CI) values were estimated using logistic regression.We found that alcohol drinkers had a was up to seven...
Pullulan is a kind of natural polymer, which widely used in medicine and food because its solubility, plasticity, edible, non-toxicity good biocompatibility. It great significance to improve the yield pullulan by genetic modification microorganisms. was previously reported that Aureobasidium melanogenum TN3-1 isolated from honey-comb could produce high-yield pullulan, but molecular mechanisms production had not been completely solved. In this study, strains spp. were further compared...