A5033937923- Tryptophan and brain disorders
- Alzheimer's disease research and treatments
- Neurological Disease Mechanisms and Treatments
- Neurological Disorders and Treatments
- Nuclear Receptors and Signaling
- Neuroinflammation and Neurodegeneration Mechanisms
- GDF15 and Related Biomarkers
- Toxin Mechanisms and Immunotoxins
- Hereditary Neurological Disorders
- RNA modifications and cancer
- Fungal Infections and Studies
- Dental Implant Techniques and Outcomes
- Total Knee Arthroplasty Outcomes
- RNA regulation and disease
- Cerebrovascular and genetic disorders
- Antifungal resistance and susceptibility
- Long-Term Effects of COVID-19
- Vitamin D Research Studies
- Quantum Dots Synthesis And Properties
- Macrophage Migration Inhibitory Factor
- Dementia and Cognitive Impairment Research
- Infectious Diseases and Mycology
- Multiple Sclerosis Research Studies
- COVID-19 and Mental Health
- Nanoparticles: synthesis and applications
University of Siena
2022-2025
Center for Neurosciences
2025
Precision for Medicine (United States)
2022
Background To assess whether SARS-CoV-2 infection may affect the central nervous system, specifically neurons and glia cells, even without clinical neurological involvement. Methods In this single centre prospective study, serum levels of neurofilament light chain (sNfL) glial fibrillar acidic protein (sGFAp) were assessed using SimoaTM assay Neurology 2-Plex B Assay Kit, in 148 hospitalised patients with COVID-19 manifestations compared them to 53 interstitial pulmonary fibrosis (IPF) 108...
Background: Despite their potential usefulness as biomarkers, no study has investigated the interactions between cerebrospinal fluid (CSF) changes of neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), growth differentiation factor 15 (GDF-15), transactive response DNA binding (TDP-43) and interleukin-6 (IL-6) core AD CSF biomarkers in same cohort patients. Objectives: The aim this pilot is to evaluate levels these analytes patients with assess clinical relevance...
Abstract Background Hereditary transthyretin amyloidosis (ATTRv) is a rare disorder caused by pathogenic TTR gene variants. Glial fibrillary acidic protein (GFAP) and neurofilament light chain (NfL) are potential biomarkers for astrocyte activation neuroaxonal damage, respectively. This study investigates serum GFAP (sGFAP) NfL (sNfL) levels in ATTRv patients, pre-symptomatic subjects, healthy controls (HCs) to evaluate their utility as of disease progression CNS involvement. Methods Our...
The objective of this case report was to describe the first
Edentulism is one of the most significant problems given increase in elderly population. The aim present investigation to evaluate a case report with angled screwdriver solutions and new kinds low-profile attachments full arch rehabilitation divergent implants. In this clinical we will analyze how abutments channel OT Bridge system (Rhein83, Bologna, Italy) can be predictable solution over time create fixed prosthesis on disparallel implants digital structure (New Ancorvis, for satisfaction...
Creutzfeldt-Jakob disease (CJD) is a rapidly progressive neurodegenerative disorder characterized by neuronal damage. Emerging biomarkers, such as serum neurofilament light chain (sNfL), glial fibrillary acidic protein (sGFAP), and growth differentiation factor-15 (sGDF-15), are currently being studied for their potential use in this disease.
A 72-year-old man, trader, from Central America was admitted to the neurologic unit in Grosseto after 2 weeks onset of balance disturbances and headache.Two days before, a low-grade fever developed, his wife brought him hospital.Neurological examination showed dysarthria, bilateral nystagmus, ataxia.Brain CT multiple low-density non-enhancing cerebellar lesions diffuse edema (Fig. 1).Brain MRI revealed hyperintense areas T2-weighted sequences whole cerebellum, with diffusion restriction DWI,...