- Pluripotent Stem Cells Research
- Proteoglycans and glycosaminoglycans research
- Genomics and Rare Diseases
- Genetics and Neurodevelopmental Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Peptidase Inhibition and Analysis
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Protease and Inhibitor Mechanisms
- Neurogenesis and neuroplasticity mechanisms
Southern Medical University
2019
Nanfang Hospital
2019
Rutgers Cancer Institute of New Jersey
2004
Rutgers, The State University of New Jersey
2004
Estrogen receptor 1 (ESR1) plays an important role in the pathological events of ovarian cancer (OV), but underlying mechanism is not completely understood. Using bioinformatics analysis, we found that ESR1 involved regulation some lncRNAs are highly expressed cancer. The might mediate roles OV occurrence and progression.This study measured expression cell lines using qRT-PCR. Some were silenced or overexpressed to determine their effects on growth invasion CAOV3 cells with stimulation 17...
Astrocytes are promising source cells to replace neurons lost disease owing a shared lineage and capacities for dedifferentiation proliferation under pathological conditions. Reprogramming of astrocytes has been achieved by transcription factor modulation, but reprogramming in vitro or vivo using small‐molecule drugs may have several advantages clinical application. For instance, small molecules can be extensively characterized efficacy, toxicity, tumorigenicity vitro; induce rapid...
The identification of mental health disorders and dementia in individuals with intellectual developmental disability is complex. This due to possible overlapping clinical presentations the difficulty separating symptoms from characteristics disability. Furthermore, intrinsic limitations communication challenges faced elucidating accurate information presence these conditions lend additional difficulty. However, differentiating between essential for establishing diagnoses instituting...