- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Structural Load-Bearing Analysis
- Toxic Organic Pollutants Impact
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pesticide Residue Analysis and Safety
- Analytical chemistry methods development
- Proteins in Food Systems
- Reproductive System and Pregnancy
- 3D Surveying and Cultural Heritage
- RNA Research and Splicing
- Geomechanics and Mining Engineering
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Peptidase Inhibition and Analysis
- Chromatin Remodeling and Cancer
- Metal Forming Simulation Techniques
- Mass Spectrometry Techniques and Applications
- Cancer Immunotherapy and Biomarkers
- Endometrial and Cervical Cancer Treatments
- Structural Engineering and Materials Analysis
- Animal Diversity and Health Studies
- Advanced Glycation End Products research
- Plant-based Medicinal Research
- Concrete Corrosion and Durability
Hainan General Hospital
2019-2025
Hainan Medical University
2022-2025
Chinese Center For Disease Control and Prevention
2024
Hainan Provincial Hospital of Traditional Chinese Medicine
2016-2017
Estrogen receptor 1 (ESR1) plays an important role in the pathological events of ovarian cancer (OV), but underlying mechanism is not completely understood. Using bioinformatics analysis, we found that ESR1 involved regulation some lncRNAs are highly expressed cancer. The might mediate roles OV occurrence and progression.This study measured expression cell lines using qRT-PCR. Some were silenced or overexpressed to determine their effects on growth invasion CAOV3 cells with stimulation 17...
// Tianbo Jin 1, 2, 3, 4, * , Xiaohong Wu 5, Hua Yang 4 Ming Liu 6 Yongjun He 3 Xue Xugang Shi Fengjiao Wang Shuli Du Yajuan Ma Shan Bao 7 Dongya Yuan 1 Key Laboratory of Molecular Mechanism and Intervention Research for Plateau Diseases Tibet Autonomous Region, School Medicine, Xizang Minzu University, Xianyang, Shaanxi 712082, China 2 High Altitude Environment Genes Related to Basic Life Science Xi’an Tiangen Precision Medical Institute, Xi’an, 710075, 5 Department Maternity...
We explored the correlation between single nucleotide polymorphisms (SNPs) and susceptibility to cervical cancer (CC) in a Xinjiang Uygur population. Ten SNPs eight miRNA-regulated genes were selected for analysis. Odds ratios (ORs) 95% confidence intervals (95% CIs) calculated using unconditional logistic regression Multivariate analysis was used detect correlations CC. found that minor allele "C" of rs512715 NEAT1 associated with an increased risk CC allele, codominant, dominant,...
Abstract Background Recently, many studies have identified that genetic factor plays a crucial role in endometrial cancer development. The purpose of this study is to investigate the influence single nucleotide polymorphisms (SNPs) IL‐1R2 on susceptibility. Methods We performed case‐control included 293 patients with and 579 healthy controls. Six SNPs gene were genotyped using Agena MassARRAY platform. Genetic models haplotype analyses used assess association between risk by computing odds...
Abstract Persistent organochlorine pollutants (POCPs) are a group of “forever chemicals” that ubiquitous in the environment and pose adverse health effects to humans. However, lack sensitive widely applicable analytical method for internal POCPs exposure assessment puts limits on researches risk evaluations. Therefore, we have developed validated an simultaneously determine 43 small amount human serum (0.25 mL) with high sensitivity, low matrix effect, cost. With combination liquid-liquid...
Endometrial carcinoma (EC) is one of the most common malignant gynecological malignancies. BCL11A gene may have a tumor-suppressor role in EC. Until now, no studies reported effect variants on EC predisposition Chinese population.Six polymorphisms were genotyped using Agena MassARRAY system among 509 patients and 506 matched healthy women. Risk assessment for risk was performed by calculating odds ratios (OR) with 95% confidence intervals (CI) through logistic regression models.We found that...