Jing Fang

ORCID: 0000-0002-7357-8976
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About
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Research Areas
  • Thyroid and Parathyroid Surgery
  • Demographic Trends and Gender Preferences
  • RNA modifications and cancer
  • Cancer Genomics and Diagnostics
  • MicroRNA in disease regulation
  • Thyroid Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Zoonotic diseases and public health
  • Circular RNAs in diseases
  • Head and Neck Anomalies
  • Cancer-related molecular mechanisms research
  • Obesity, Physical Activity, Diet
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Global Maternal and Child Health
  • Airway Management and Intubation Techniques
  • Physical Activity and Health
  • Gestational Trophoblastic Disease Studies
  • Child Nutrition and Water Access
  • Antibiotic Use and Resistance
  • Nephrotoxicity and Medicinal Plants
  • Ovarian cancer diagnosis and treatment
  • COVID-19 epidemiological studies
  • Congenital Diaphragmatic Hernia Studies
  • Ocular Infections and Treatments
  • Corneal Surgery and Treatments

University of Science and Technology of China
2020-2025

Anhui Medical University
2025

Anhui Provincial Hospital
2021-2025

Second Hospital of Anhui Medical University
2025

Qingdao University
2023-2024

Affiliated Hospital of Qingdao University
2023-2024

National Health and Family Planning Commission
2024

Kunming Medical University
2008-2023

Sichuan Agricultural University
2012-2023

Zhongshan Hospital of Xiamen University
2023

Lineage transition in adenocarcinoma (ADC) and squamous cell carcinoma (SCC) of non-small lung cancer, as implicated by clinical observation mixed ADC SCC pathologies adenosquamous carcinoma, remains a fundamental yet unsolved question. Here we provide vivo evidence showing the transdifferentiation cancer from to mice: Lkb1-deficient progressively transdifferentiates into SCC, via pathologically mAd-SCC intermediate. We find that reduction lysyl oxidase (Lox) decreases collagen disposition...

10.1038/ncomms4261 article EN cc-by-nc-nd Nature Communications 2014-02-17

Background The Sustainable Development Goals (SDGs), adopted by all United Nations (UN) member states in 2015, established a set of bold and ambitious health-related targets to achieve 2030. Understanding China's progress toward these is critical improving population health for its 1.4 billion people. Methods findings We used estimates from the Global Burden Disease (GBD) Study 2016, national surveys surveillance data China, qualitative data. Twenty-eight 37 indicators included GBD 2016 were...

10.1371/journal.pmed.1002975 article EN cc-by PLoS Medicine 2019-11-19

Litchi is an important fruit tree in tropical and subtropical areas of the world. However, there widespread confusion regarding litchi cultivar nomenclature detailed information genetic relationships among germplasm unclear. In present study, potential single nucleotide polymorphism (SNP) for identification 96 representative accessions their China was evaluated using 155 SNPs that were evenly spaced across genome. Ninety with minor allele frequencies above 0.05 a good genotyping success rate...

10.1371/journal.pone.0135390 article EN cc-by PLoS ONE 2015-08-11

Circulating tumor DNA (ctDNA) has been becoming a novel convenient and noninvasive method for dynamically monitoring landscape of genomic information to guild personalized cancer treatment. In this study we comprehensively evaluated the additional value plasma ctDNA routine tissue next generation sequencing (NGS) therapeutically targetable mutations in lung cancers.The tissues peripheral blood samples from 423 cases patients with were subjected NGS oncodrivers (EGFR, ERBB2, ALK, ROS1, C-MET,...

10.1186/s12885-023-10674-z article EN cc-by BMC Cancer 2023-03-31

Soy isoflavones are natural active ingredients of soy plants that beneficial to many metabolic diseases, especially obesity. Many studies have reported obesity is closely related visceral fatty acid metabolism, but the effect has not been well defined. In this study, we show improve metabolism in diet-induced obese male rats, which was indicated by reduced body weight and fat cell area, as suppressed synthesis accelerated hydrolysis. We also found common components isoflavones, daidzein...

10.3390/molecules24152809 article EN cc-by Molecules 2019-08-01

Background/Aims: Excessive fluoride intake can induce cytotoxicity, DNA damage and cell-cycle changes in many tissues organs, including the kidney. However, underlying molecular mechanisms of fluoride-induced renal are not well understood at present. In this study, we used a mouse model to investigate how sodium (NaF) induces cells. Methods: Two hundred forty ICR mice were randomly assigned four equal groups for intragastric administration NaF (0, 12, 24 48 mg/kg body weight/day) 42 days....

10.1159/000495899 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2018-01-01

Antibiotic residues contained in poultry eggs pose threat to human health. However, the classes and concentrations of antibiotics egg southwestern China is unknown due insufficient monitoring research. A total 513 samples were collected from supermarkets farm markets Kunming city 2020 levels 7 analyzed using ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method. The linear correlation coefficients above 0.990 for all tested. limits detection...

10.1016/j.psj.2022.101892 article EN cc-by-nc-nd Poultry Science 2022-03-31

This study aimed to summarize and explore how establish a good surgical space via gasless transoral endoscopic thyroidectomy vestibular approach (TOETVA) facilitate smooth progress. was conducted between January 2022 December 2023. The involved 281 patients with papillary thyroid carcinoma who underwent TOETVA at First Affiliated Hospital of the University Science Technology China. suspension method used during operation. key steps difficulties construction were summarized,...

10.1186/s12957-025-03708-2 article EN cc-by-nc-nd World Journal of Surgical Oncology 2025-02-18

Abstract Background Sexual and Reproductive Health (SRH) targets have been included as part of the United Nations Sustainable Development Goals indictors are important to monitor progress towards these targets. SRH indicators recommended for setting norms measuring globally. However, given diverse political, socioeconomic cultural contexts in different countries, lack global agreement on broad indicators, it is select appropriate specific countries. Based internationally data availability...

10.1186/s12978-020-00924-9 article EN cc-by Reproductive Health 2020-06-01
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