A5100323279- Diet, Metabolism, and Disease
- Enzyme Production and Characterization
- Adipokines, Inflammation, and Metabolic Diseases
- Sperm and Testicular Function
- Epigenetics and DNA Methylation
- Phytoestrogen effects and research
- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Regulation of Appetite and Obesity
- Antibiotics Pharmacokinetics and Efficacy
- Fungal Biology and Applications
- Autophagy in Disease and Therapy
- Genomics, phytochemicals, and oxidative stress
- Cell Adhesion Molecules Research
- Protein Hydrolysis and Bioactive Peptides
- Metabolism, Diabetes, and Cancer
- Bioactive natural compounds
- Medicinal Plant Pharmacodynamics Research
- Reproductive Biology and Fertility
- Phytase and its Applications
Sichuan Agricultural University
2018-2023
The high recurrence frequency of gliomas but deficiency effective treatment and prevalent chemoresistance have elicited interests in exploring developing new agents. Paris polyphyllins are monomers extracted from rhizome polyphylla var. yunnanensis. Here, we first reported that polyphyllin VII (PP7) exhibited cytotoxic effect on glioma cells. PP7 significantly suppressed the viability induced cell death U87-MG U251 cells after 24 h, with IC50 values <mml:math...
The strain Y1, with a notably high production of neutral protease, was isolated from naturally fermented broad beans and subsequently identified as Aspergillus oryzae, through the analysis its morphology characteristics 18S rDNA sequence. Naturally are main raw material in Sichuan broad-bean sauce. protease oryzae Y1 purified using ammonium sulphate precipitation DEAE-Sepharose Fast Flow chromatography, which resulted 10.0-fold increase specific activity (2264.3 U/mg) recovery rate 21%....
Soy isoflavones are natural active ingredients of soy plants that beneficial to many metabolic diseases, especially obesity. Many studies have reported obesity is closely related visceral fatty acid metabolism, but the effect has not been well defined. In this study, we show improve metabolism in diet-induced obese male rats, which was indicated by reduced body weight and fat cell area, as suppressed synthesis accelerated hydrolysis. We also found common components isoflavones, daidzein...
The morbidity and mortality of primary liver cancer is one the highest amongst all cancers. Deficiency effective treatment characteristics metastasis are believed to be responsible for this situation, thus a great demand required new agent development. Polyphyllin II (PP2), an important steroidal saponin extracted from Rhizoma Paris, has emerged as potential anti-cancer agent, but effects PP2 in cancers its underlying mechanisms remain unexplored. In our study, we found that could remarkably...
Obesity is a common metabolic disorder that increases the risk of many diseases, such as type II diabetes, hypertension, cardiovascular disease.Hypothalamus plays very important role in progression obesity, and studies reveal hypothalamic injures are implicated obesity processes.Here, we describe consumption soy isoflavones, with structural similarity to estradiol, could mitigate through improving inflammation apoptosis, which induced by oxidative stress.Also, our vitro demonstrate daidzein...
Florfenicol(FF) is an excellent veterinary antibiotic, limited by poor solubility and bioavailability.