A5057826341- Medical Imaging Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Diet and metabolism studies
- Animal testing and alternatives
- Ultrasound and Hyperthermia Applications
- Muscle metabolism and nutrition
- Advanced X-ray and CT Imaging
- Metabolism and Genetic Disorders
Aarhus University Hospital
2021-2024
The ketone body 3-hydroxybutyrate (3-OHB) increases cardiac output (CO) by 35% to 40% in healthy people and with heart failure. mechanisms underlying the effects of 3-OHB on myocardial contractility loading conditions as well cardiovascular its enantiomeric forms, D-3-OHB L-3-OHB, remain undetermined.
In preclinical positron emission tomography animal studies, continuous blood sampling is used to measure the time course of activity concentration in arterial blood. However, pigs have hypercoagulable that tends clot inside plastic tubes. We tested several tube materials and lengths use three-way connectors. validated set-ups for automated with without recirculation could run 90 minutes problematic clots any evidence emboli formation during necropsy.