A5101655971- Traditional Chinese Medicine Analysis
- Traditional Chinese Medicine Studies
- Cardiac Health and Mental Health
- Lipid metabolism and disorders
- Liver Disease Diagnosis and Treatment
- Inflammasome and immune disorders
- Heart Rate Variability and Autonomic Control
- Computational Drug Discovery Methods
- Cardiovascular Disease and Adiposity
- Atherosclerosis and Cardiovascular Diseases
- Autophagy in Disease and Therapy
- Ginseng Biological Effects and Applications
- Plant-based Medicinal Research
- Sepsis Diagnosis and Treatment
- Pharmacological Effects of Natural Compounds
- Lipoproteins and Cardiovascular Health
- Tryptophan and brain disorders
- Hormonal Regulation and Hypertension
- Music Therapy and Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Inflammation biomarkers and pathways
- Diet, Metabolism, and Disease
- Cancer, Lipids, and Metabolism
- Mitochondrial Function and Pathology
Shenzhen Pingle Orthopedic Hospital
2016-2025
Guangzhou University of Chinese Medicine
2017-2025
Southwest Medical University
2025
Macau University of Science and Technology
2021-2024
Anhui Medical University
2023
Czech Academy of Sciences, Institute of Physiology
2023
University of Macau
2023
Guangzhou University
2019-2022
Weatherford College
2022
Development Fund
2022
Myocardial ischemia/reperfusion (I/R) injury is the main cause of increasing postischemic heart failure and currently there no definite treatment for myocardial I/R injury. It has been suggested that oxidative stress-induced mitochondrial dysfunction plays an important role in pathological development I/R. In this study, Yiqi Huoxue (YQHX) prescription, as a kind Chinese herbal formula, was developed shown to alleviate Network analysis combined with ultrahigh-performance liquid...
Metabolism under hypoxia is significantly different from that normoxia. It has been well elucidated HIF-1 (hypoxia-inducible factor-1) plays a central role in regulating glucose metabolism hypoxia; however, the of lipid not yet addressed. In present study we demonstrate promotes LDL (low-density lipoprotein) and VLDL (very-LDL) uptake through regulation VLDLR (VLDL receptor) gene expression hypoxia. Increased mRNA protein levels were observed hypoxic or DFO (deferoxamine mesylate salt)...
Nucleotide analogs treatment can reverse liver fibrosis in chronic hepatitis B (CHB). However, it has limited effect on resolution patients with CHB, particularly preventing progression to hepatocellular carcinoma (HCC). Ruangan granule (RG), a Chinese herbal formula, proven produce therapeutic against animal experiment. Thus, we aimed evaluate the of our formula (RG) combined entecavir (ETV) advanced fibrosis/early cirrhosis from CHB. A total 240 CHB histologically confirmed 12 centers were...
Background: Myocardial infarction (MI) is a common critical syndrome in the late development of cardiovascular diseases (CVDs), and traditional Chinese Medicine (TCM) treatment has become an essential branch this field. Objective: This study aimed to use bibliometric methods examine research trajectory TCM MI from 2007 2024 multidimensional perspective analyse its characteristics, hotspots, frontiers. Methods: used search formula TS OR TI AB A (“traditional medicine” or “Chinese “TCM”...
Epidemiological evidence suggests that non-alcoholic fatty liver disease (NAFLD) may increase the risk of atrial fibrillation (AF). However, findings are inconsistent, and causality remains to be established. We conducted two-step, two-sample Mendelian randomization (MR) analysis assess association between genetically predicted NAFLD (i.e. chronically elevated serum alanine aminotransferase levels [cALT], imaging-based biopsy-confirmed NAFLD) AF. Subsequently, we further performed...
Danshen Decoction comprises Salvia miltiorrhiza, Santalum album, and Amomum villosum. It can promote blood circulation remove stasis, is commonly used in the treatment of gastric duodenal ulcers, coronary heart disease, angina pectoris, etc. This research based on network pharmacology experimentally verified to explore potential mechanism ischemic cardiomyopathy (ICM).The effective components targets were firstly extracted from Traditional Chinese Medicine Systems Pharmacology (TCMSP)...
Nonalcoholic steatohepatitis (NASH) has caused a significant burden on public health care systems, the economy and society. However, there still been no officially approved pharmacotherapy for NASH. It suggested that oxidative stress mitochondrial dysfunction play vital roles in NASH pathological progression. Shugan Xiaozhi (SG) formula, as kind of classical herbal was shown to attenuate NASH.This study aimed explore potential mechanisms SG formula treating NASH.Ultra-high-performance liquid...
Objective This study aimed to explore the association between triglyceride high-density lipoprotein cholesterol (TG/HDL-C) ratio and risk severity of CHD among NAFLD patients. Methods retrospective included 278 patients with chest pain. The TG/HDL-C was calculated coronary angiography performed. All individuals were divided into + groups. artery stenosis is quantified using Gensini score based on angiographic results. In patients, explored. Results detected in 139 Compared group,...
BackgroundXiaoyaosan (XYS), a renowned classical traditional Chinese medicinal formula utilized in addressing major depressive disorder (MDD), has garnered significant acclaim for its remarkable efficacy clinical application. The onset of (MDD) often correlates with chronic unpredictable mild stress (CUMS), pivotal instigating factor development.Aim the study: This study aims to clarify potential anti-inflammatory mechanisms XYS treating CUMS model mice.Materials and methodsUtilizing...