A5103272875- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ultrasound in Clinical Applications
- Birth, Development, and Health
- Assisted Reproductive Technology and Twin Pregnancy
- Colorectal Cancer Surgical Treatments
- Biomarkers in Disease Mechanisms
- Colorectal and Anal Carcinomas
- Ultrasound and Hyperthermia Applications
- Maternal Mental Health During Pregnancy and Postpartum
- COVID-19 Impact on Reproduction
- Cardiovascular Issues in Pregnancy
- Salivary Gland Disorders and Functions
- Pleural and Pulmonary Diseases
- Cerebrovascular and Carotid Artery Diseases
- Inflammatory Myopathies and Dermatomyositis
- Pregnancy and preeclampsia studies
- Cardiovascular Health and Disease Prevention
- COVID-19 and Mental Health
- Cardiac Imaging and Diagnostics
- Salivary Gland Tumors Diagnosis and Treatment
- Micro and Nano Robotics
- Molecular Communication and Nanonetworks
- Lung Cancer Diagnosis and Treatment
- Axon Guidance and Neuronal Signaling
- Ectopic Pregnancy Diagnosis and Management
First Affiliated Hospital of Shantou University Medical College
2016-2025
Shantou University
2014-2024
Anhui University of Traditional Chinese Medicine
2023
Huazhong University of Science and Technology
2021
Wuhan Union Hospital
2021
Zhejiang Sci-Tech University
2015
First Affiliated Hospital of Fujian Medical University
2014
First Affiliated Hospital of Wenzhou Medical University
2008-2010
Wenzhou Medical University
2008-2010
Qingdao Huanghai University
2007
Tobacco exposure is considered to be a risk factor for reduced bone mineral density (BMD), which may result in osteopenia. Cotinine, metabolite of nicotine, commonly utilized as marker tobacco exposure. Nevertheless, there are limited clinical data on the associations between osteoporosis (OP) or osteopenia and smoking status serum cotinine level.We thoroughly examined NHANES cross-sectional from 2005 2010, 2013 2014, 2017 2018. Multivariate logistic regression models were applied assess...
Objectives Familial aggregation of primary Sjögren’s syndrome (pSS), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and co-aggregation these autoimmune diseases (ADs) (also called familial autoimmunity) is well recognised. However, the genetic predisposition variants that explain this clustering remains poorly defined. Methods We used whole-exome sequencing on 31 families (9 pSS, 11 SLE, 6 RA 5 mixed autoimmunity), followed by heterozygous filtering cosegregation analysis a...
Abstract Objective Idiopathic inflammatory myositis-associated interstitial lung disease (IIM-ILD) significantly increases morbidity and mortality. Lung ultrasound B-lines Krebs von den Lungen-6 (KL-6) are identified as new sonographic serum markers of ILD, respectively. The aim our work was to assess the role KL-6 severity IIM-ILD. For this purpose, correlation among score, levels, high-resolution CT (HRCT) pulmonary function tests were investigated in IIM-ILD patients. Methods Thirty-eight...
This prospective study aimed to investigate the use of real-time three-dimensional hysterosalpingo-contrast sonography (4D-HyCoSy), using contrast agent SonoVue, with B mode (B mode-HyCoSy), evaluate tubal patency and wall Fallopian tubes in infertility patients.In total, we recruited 739 women fertility requirements from First Affiliated Hospital Shantou Medical College between January 2017 July 2018. All cases received 4D-HyCoSy immediately followed by mode-HyCoSy. Of these patients, 145...
A total of 136 subjects (51 SS patients, 35 sicca syndrome patients without SS, and 50 healthy volunteers) were enrolled in this study. The mean SWV value for salivary glands was statistically higher than that controls (2.81 ± 0.66 m/s versus 1.85 0.28 parotid 2.29 0.34 1.82 0.25 submandibular glands, resp.). Combining values gives a sensitivity 88.2% (95% CI: 76.1–95.6%) specificity 96.0% 86.3–99.5%) at the cutoff point 2.19 m/s, with an AUROC 0.954 0.893–0.986). In addition, combining SGUS...
Abstract Background To date, there is no approved blood‐based biomarker for breast cancer detection. Herein, we aimed to assess semaphorin 4C (SEMA4C), a pivotal protein involved in progression, as serum diagnostic biomarker. Methods We included 6,213 consecutive inpatients from Tongji Hospital, Qilu and Hubei Cancer Hospital. Training cohort two validation cohorts were introduced exploration validation. A pan‐cancer was used independently explore the potential of SEMA4C among solid tumors....
Objectives To investigate the value of salivary gland stiffness measured by Virtual Touch quantification (VTQ; Siemens Medical Solutions, Erlangen, Germany) for assessment primary Sjögren syndrome. Methods Fifty‐four patients with syndrome, 35 without syndrome (patients dry mouth and eye symptoms), 52 healthy control volunteers were included in this study. Patients classified as early or advanced stage labial biopsies. All participants underwent B‐mode sonography, on which glands (parotid...
The purpose of this study was to investigate the value Virtual Touch tissue quantification (Siemens Medical Solutions, Erlangen, Germany) for differentiation benign and malignant superficial lymph node lesions.Shear wave velocity (SWV) values were analyzed in 113 patients, who also had diagnoses by pathologic examination. diagnostic performance SWV evaluated sensitivity specificity at optimum cutoff area under receiver operating characteristic curve (AUROC).A total 60 lesions (32 reactive...
To investigate the role of serum B-cell activating factor (BAFF) and lung ultrasound (LUS) B-lines in connective tissue disease related interstitial (CTD-ILD), their association with different ILD patterns on high resolution computed tomography (HRCT) chest.We measured levels BAFF KL-6 by ELISA sera 63 CTD-ILD patients [26 fibrotic (F-ILD), 37 non-fibrotic (NF-ILD)], 30 CTD without ILD, 26 healthy controls. All underwent chest HRCT LUS examination.Serum were significantly higher compared to...
Abstract Background COVID-19(Corona Virus Disease 2019) outbreaks around the world and is highly infectious, which may cause people prone to anxiety depression. As a particular group, pregnant women need more attention. The aim of study investigate mental health status during outbreak COVID-19, analyze factors affecting women. Methods Using self-designed questionnaire, self-rated scale(SAS), depression scale (SDS), we conducted web-based survey on 1160 COVID-19. Results Compared with general...
B-Lines are a new sonographic hallmark of connective tissue disease–associated interstitial lung diseases (CTD-ILDs). Promising data have shown that B-lines associated with high-resolution CT (HRCT), pulmonary function test and some clinical variables, expanding the armamentarium for screening ILDs.1 Krebs von den Lungen-6 (KL-6) antigen is mucin-like, high molecular weight glycoprotein expressed on surface membrane alveolar epithelial cells Ⅱ bronchiolar cells, increases following cellular...
Ultrasonography is the preferred technique to evaluate status of maternal and fetal health during pregnancy. Non-obstetric acute or chronic conditions occurring pregnancy must be diagnosed as early possible permit timely necessary treatment for sake health. The purpose this study was safety value contrast-enhanced ultrasonography (CEUS) pregnancy.This prospective included 14 pregnant women requiring termination six healthy women. underwent CEUS prior surgery investigate pattern contrast...
Abstract Background: COVID-19(Corona Virus Disease 2019) outbreaks around the world and is highly infectious, which may cause people prone to anxiety depression. Pregnant women, as a particular group, need more attention. The aim of this study investigate mental health status pregnant women during outbreak COVID-19, analyze factors affecting their status, get wise cognition, behavioral responses provide solution guidance for psychological problems. Methods: Using self-designed questionnaire,...
Background and objective To explore the potential clinical usefulness determine optimal diagnostic criteria of quantitative tissue velocity imaging anatomic M-mode echocardiography in patients with coronary artery disease (CAD). Methods We used for measurement systolic myocardial velocity, ventricular wall-thickening fraction 44 subjects suspected CAD. Subjects were classified as if angiography demonstrated a stenosis ≥50%, controls it was strictly normal. The criteria, sensitivity,...
Excessive placental invasion is a life-threatening obstetric disease. Determining the extent of villi prenatally crucial for formulating surgical plan pregnant women. The objective this study was to explore diagnostic accuracy Crystal Vue technique combined with two-dimensional (2D) ultrasound in detecting degree placenta accreta spectrum (PAS) located C-section scar area.Twenty-seven women strong suspicion PAS underwent 2D examination. diagnosis alone and statistically calculated,...
Objective To address the neural basis of Chinese idioms processing with different kinds stimuli using an event-related fMRI design.Methods Sixteen native speakers were asked to perform a semantic decision task during scanning.Three used: Real (Real-idiom condition);Literally plausible phrases (Pseudo-idiom condition,the last character real idiom was replaced by similar meaning);Literally implausible strings (Non-idiom unrelated meaning).Reaction time and correct rate recorded at same...
Abstract Background COVID-19(Corona Virus Disease 2019) outbreaks around the world and is highly infectious, which may cause people prone to anxiety depression. Pregnant women, as a particular group, need more attention. The aim of this study investigate mental health status pregnant women during outbreak COVID-19, analyze factors affecting their status, understand cognition, behavioral responses provide solution guidance for psychological problems. Methods Using self-designed questionnaire,...