Wenyuan Hou

ORCID: 0000-0003-1436-6903
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About
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Research Areas
  • Osteoarthritis Treatment and Mechanisms
  • Knee injuries and reconstruction techniques
  • Bone health and osteoporosis research
  • Bone and Joint Diseases
  • Bone fractures and treatments
  • Hematological disorders and diagnostics
  • Pregnancy-related medical research
  • Biomarkers in Disease Mechanisms
  • Economic Development and Regional Competitiveness
  • Total Knee Arthroplasty Outcomes
  • Labor Market and Education
  • Gut microbiota and health
  • Bone Metabolism and Diseases
  • Dermatological and COVID-19 studies
  • Hip disorders and treatments
  • Nutrition and Health in Aging
  • Socio-economic Development and Sustainability
  • Heme Oxygenase-1 and Carbon Monoxide

Guangzhou University of Chinese Medicine
2023-2025

Anhui University of Traditional Chinese Medicine
2022-2023

Tobacco exposure is considered to be a risk factor for reduced bone mineral density (BMD), which may result in osteopenia. Cotinine, metabolite of nicotine, commonly utilized as marker tobacco exposure. Nevertheless, there are limited clinical data on the associations between osteoporosis (OP) or osteopenia and smoking status serum cotinine level.We thoroughly examined NHANES cross-sectional from 2005 2010, 2013 2014, 2017 2018. Multivariate logistic regression models were applied assess...

10.3389/fendo.2023.1074574 article EN cc-by Frontiers in Endocrinology 2023-02-03

To investigate the impact of bone mass and volume low-density zones beneath tibial plateau on maximum von Mises stresses experienced by cartilage meniscus in knee joint. The study included one healthy adult volunteer, from whom CT scans were obtained, patient diagnosed with osteoarthrisis (KOA), for X-ray films acquired. A static model joint featuring a zone was established based normal model. In finite element analysis, axial loads 1 000 N 800 applied to weight-bearing region upper surface...

10.7507/1002-1892.202412018 article EN PubMed 2025-03-15

Numerous surgical interventions are available for the treatment of knee osteoarthritis (KOA). In recent years, knee-preserving surgery, specifically osteotomy, has gained significant attention from patients, particularly those who young and physically active, as it not only effectively alleviates pain but also preserves bone integrity, thereby allowing potential future joint replacement. This study aims to comprehensively analyze global application trends osteotomy KOA identify current...

10.1097/md.0000000000037036 article EN cc-by-nc Medicine 2024-02-16

<title>Abstract</title> Background: Autophagy is closely associated with the onset and progression of steroid-induced osteonecrosis femoral head (SIONFH). SQSTM1/p62 an important indicator autophagic activity. The aim this study was to investigate role in development SIONFH. Methods: From May 2021 through November 2021, 36 patients diagnosed SIONFH healthy controls were recruited for study. Evaluations included imaging pathologic assessment clinical bone tissue, location level expression,...

10.21203/rs.3.rs-4265724/v1 preprint EN Research Square (Research Square) 2024-04-29

To investigate the impact of bone mass and volume low-density area under tibial plateau on lower limb force line by finite element analysis, offering mechanical evidence for preventing internal displacement in conjunction with knee varus patients osteoarthritis (KOA) reducing plateau.

10.7507/1002-1892.202312026 article EN PubMed 2024-06-15

Autophagy is closely associated with the onset and progression of steroid-induced osteonecrosis femoral head (SIONFH). SQSTM1/p62 an important indicator autophagic activity. The aim this study was to investigate role in development SIONFH. From May 2021 through November 2021, 36 patients diagnosed SIONFH healthy controls were recruited for study. Evaluations included imaging pathologic assessment clinical bone tissue, location level expression, plasma levels, receiver operating...

10.1038/s41598-024-71743-2 article EN cc-by-nc-nd Scientific Reports 2024-10-22

Abstract Background Osteoporosis (OP) is a chronic systemic metabolic bone disease. As the population ages, prevalence of OP gradually increasing, making it one significant public health problems worldwide. The gut microbiota (GM) complex microbial ecosystem that can affect metabolism through multiple pathways. Therefore, understanding potential pathogenesis GM crucial for preventing and treating OP. Methods We conducted literature search encompassing English-language studies on relationship...

10.21203/rs.3.rs-3469687/v1 preprint EN cc-by Research Square (Research Square) 2023-10-24
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