A5088602459- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Facial Trauma and Fracture Management
- Bone Tissue Engineering Materials
- Dental Radiography and Imaging
- Oral and Maxillofacial Pathology
- Orthodontics and Dentofacial Orthopedics
- Dental Implant Techniques and Outcomes
- Reconstructive Surgery and Microvascular Techniques
- dental development and anomalies
- Traumatic Ocular and Foreign Body Injuries
- Temporomandibular Joint Disorders
- Bone Tumor Diagnosis and Treatments
- Head and Neck Surgical Oncology
- Periodontal Regeneration and Treatments
- Facial Nerve Paralysis Treatment and Research
- Salivary Gland Tumors Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Tracheal and airway disorders
- Reconstructive Facial Surgery Techniques
- Mesenchymal stem cell research
- Facial Rejuvenation and Surgery Techniques
- Oropharyngeal Anatomy and Pathologies
- Nasal Surgery and Airway Studies
- Oral and Craniofacial Lesions
Inserm
2012-2025
Nantes Université
2016-2025
Oniris
2021-2025
Charles University
2025
Centre Hospitalier Universitaire de Nantes
2015-2024
Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers
2024
RMeS - Regenerative Medicine and Skeleton
2022-2024
Centre National de la Recherche Scientifique
2024
Clinique Jules Verne
2022
Centre Hospitalier Saint-Nazaire
2022
The field of dysmorphology has been changed by the use Artificial Intelligence (AI) and development Next Generation Phenotyping (NGP). aim this study was to propose a new NGP model for predicting KS (Kabuki Syndrome) on 2D facial photographs distinguish KS1 (KS type 1, KMT2D-related) from KS2 2, KDM6A-related). We included retrospectively prospectively, 1998 2023, all frontal lateral pictures patients with molecular confirmation KS. After automatic preprocessing, we extracted geometric...
Cleft lip and/or palate is the most common congenital orofacial deformity, affecting 1/800 births. A thorough review of literature has shown that children with cleft have poorer oral hygiene and dental health than other children, higher levels caries in both temporary permanent teeth periodontal health. patients are treated by a multidisciplinary team aims to provide comprehensive care from pre- or post-natal diagnosis early adulthood end growth. We aim assess, through single-center,...
Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory disease with clinical and radiological symptoms that overlap fibrous dysplasia (FD), particularly in children. This study aimed to compare the features of craniofacial CRMO FD a pediatric population. Seven children 14 were retrospectively identified our tertiary centre between 2012 2022. Their clinical, radiological, biological (when available) data collected. Two experienced radiologists reviewed imaging modalities...
Finding alternative strategies for the regeneration of craniofacial bone defects (CSDs), such as combining a synthetic ephemeral calcium phosphate (CaP) implant and/or active substances and cells, would contribute to solving this reconstructive roadblock. However, CaP's architectural features (i.e., architecture composition) still need be tailored, use processed stem cells (e.g., recombinant human morphogenetic protein 2) drastically limits clinical application approaches. Focusing on...
Growth and patterning of craniofacial sutures is subjected to the effects mechanical stress. Mechanotransduction processes occurring at margins are not precisely understood. Here, we propose a simple theoretical model based on orientation collagen fibres within suture in response local We demonstrate that fibre alignment generates an instability leading emergence interdigitations. confirm appearance this both analytically numerically. To support our model, use histology synchrotron X-ray...