A5012495920- Mosquito-borne diseases and control
- Global Maternal and Child Health
- Virology and Viral Diseases
- COVID-19 Impact on Reproduction
- Pregnancy and preeclampsia studies
- Viral Infections and Vectors
- Cardiovascular Issues in Pregnancy
- Vaccine Coverage and Hesitancy
- COVID-19 Clinical Research Studies
- Herpesvirus Infections and Treatments
- COVID-19 epidemiological studies
- Cytomegalovirus and herpesvirus research
- Insect-Plant Interactions and Control
- Bacillus and Francisella bacterial research
- Neonatal Respiratory Health Research
- Congenital Heart Disease Studies
- Epilepsy research and treatment
- Neonatal and fetal brain pathology
- Immune responses and vaccinations
- Retinal and Optic Conditions
- Neonatal and Maternal Infections
- Community Health and Development
- Breastfeeding Practices and Influences
- COVID-19 and healthcare impacts
- Cerebrospinal fluid and hydrocephalus
Universidad Nacional de Colombia
2022-2025
Instituto Nacional de Salud
2019-2024
Instituto Nacional de Salud
2023
Fundación Santa Fe de Bogotá
2022
University of Puerto Rico-Mayaguez
2020
University of Puerto Rico System
2020
Complejo Hospitalario Universitario de Toledo
2016
Project Vigilancia de Embarazadas con Zika (VEZ), an intensified surveillance of pregnant women with symptoms the virus disease (ZVD) in Colombia, aimed to evaluate relationship between ZVD during pregnancy and adverse pregnancy, birth, infant outcomes early childhood neurodevelopmental outcomes. During May–November 2016, three Colombian cities who were reported national system, or visiting participating clinics, enrolled VEZ. Data from maternal pediatric (up two years age) medical records...
We assessed maternal and infant cytomegalovirus (CMV) infection in Colombia. Maternal serum was tested for CMV immunoglobulin G antibodies at a median of 10 (interquartile range: 8-12) weeks gestation (n = 1501). DNA polymerase chain reaction performed on urine to diagnose congenital (≤21 days life) postnatal (>21 days) infection. seroprevalence 98.1% (95% confidence interval [CI]: 97.5%-98.8%). Congenital prevalence 8.4 CI: 3.9%-18.3%; 6/711) per 1000 live births. Among 472 infants without...
Abstract Background Zika virus (ZIKV) infection during pregnancy can cause infant brain and eye abnormalities has been associated with adverse neurodevelopmental outcomes in exposed infants. Evidence is limited on ZIKV’s effects children infected postnatally within the first year of life. Objective To determine whether any occurred early childhood for ZIKV infancy, given neurotoxicity rapid development that occurs infancy childhood. Methods The Colombia Instituto Nacional de Salud (INS)...
Background. Understanding COVID-19 dynamics in Colombia during the first pandemic year (2020) gives important insights surrounding population’s exposure risk and specific susceptibilities. Seroprevalence studies can aid having a broader understanding of disease, offering more inclusive view pandemic’s impact across population. Methods. A population-based cross-sectional study to assess antibodies against SARS-CoV-2 10 Colombian cities was developed between September December 2020. Cities...
Providing accurate, evidence-based information to women with Zika infection during pregnancy was problematic because of the high degree uncertainty in diagnosis and associated risk. The 2015-17 virus epidemic overwhelmingly affected countries limited access safe abortion. Understanding women's perspectives on risk communication context an emerging pathogen can help inform response future outbreaks that affect fetal or child development. We conducted a cross-sectional qualitative interview...
Abstract Background Our aim was to describe the neuroimaging and clinical evaluations of children with antenatal Zika‐virus (ZIKV) exposure. Methods The Colombian National Institute Health performed serial probable ZIKV exposure (i.e., born symptomatic mothers or birth defects compatible infection, regardless laboratory results) over 2 years that included head circumference (HC), eye examination, neurodevelopmental assessments. Clinical studies (head computed tomography and/or brain magnetic...
Background: Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection during pregnancy is related with adverse maternal, fetal, and neonatal outcomes. Placental SARS-CoV-2 involvement may include various degrees of inflammation malperfusion leading to diverse complications. Methods: Placental, fetal umbilical cord samples three demise cases that occurred in the context maternal infections were analyzed. Cases notified Colombian National Surveillance System. RT-PCR...
ABSTRACT Background Zika virus (ZIKV) infection during pregnancy can cause severe birth defects in the fetus and is associated with neurodevelopmental abnormalities childhood. Our objective was to describe ZIKV knowledge attitudes among pregnant women Colombia while circulating whether they predicted adoption of behaviors prevent mosquito-borne sexual transmission. Methods We used self-reported data from en Embarazadas y Niños (ZEN), a cohort study early across three regions 2017–2018....
Prenatal exposure to Zika virus (ZIKV) is associated with congenital anomalies of the brain and eye neurodevelopmental sequelae. The spectrum disease outcomes may relate timing infection as well genetic environmental factors. Congenital infections occurring in twin pregnancies can inform clinical these conditions provide unique information regarding utero environment pathophysiology. Herein, we report a monozygotic dichorionic-diamniotic pregnancy probable prenatal ZIKV identified through...
Prenatally transmitted viruses can cause severe damage to the developing brain. There is unexplained variability in prenatal brain injury and postnatal neurodevelopmental outcomes, suggesting disease modifiers. Discordant outcomes among dizygotic twins could be explained by genetic susceptibly or protection. Among several well-recognized threats brain, Zika a mosquito-borne, positive-stranded RNA virus that was originally isolated Uganda spread epidemics Africa, Asia, Americas. In Americas,...
Objective To describe the clinical and epidemiological characteristics of newborn infants with SARS-CoV-2 infection notified in Colombian Public Health Surveillance System. Design This descriptive analysis was conducted using data all cases confirmed surveillance system. Absolute frequencies central tendency measures were calculated a bivariate comparing variables interest symptomatic asymptomatic disease performed. Setting Population-based analysis. Patients Laboratory-confirmed COVID-19...
ABSTRACT. Zika virus (ZIKV) infection in pregnancy is associated with severe abnormalities of the brain and eye other adverse outcomes. en Embarazadas y Niños was a prospective cohort study conducted multiple Colombian cities that enrolled pregnant women their first trimester. Specimens collected from ( n = 1,519) during February 2017–September 2018 infants 1,080) June 2017–March 2019 were tested for prenatal ZIKV by nucleic acid amplification tests or IgM antibody testing. present 3.2%...
Monkeypox (mpox), caused by the MPOXV (monkeypox virus), has been endemic in Africa since its first identification 1958. However, May 2022, world witnessed global outbreak associated with West African clade. Even though thousands of cases have recorded, our understanding vertical transmission during pregnancy remains restricted due to an absence reported pregnant women and a lack adequate clinical descriptions. The two women, ages 33 24, who tested positive for at 31 13.4 weeks gestation,...
Normal pressure hydrocephalus syndrome, characterized by ventriculomegaly and the classic triad of symmetric gait disturbance, cognitive decline, urinary incontinence, is most common cause in adult population a significant reversible dementia among older adults. The only effective treatment for this to date, cerebrospinal fluid shunting procedure, commonly ventriculoperitoneal, ventriculoatrial, or lumboperitoneal shunt. success rate ranges between 73 96%. Hence, early identification, proper...
Introduction Maintaining antipsychotic therapy in mental disorder is important preventing relapse, rehospitalization, and suicide. Lack of awareness illness may be a leading cause for non-adherence. Long-acting depot can prevent non- adherence thus potentially contribute to better patient outcomes. Objective The aim this prospective, observational, non interventional 2-year-long study assess severity post-intervention changes attitudes toward medication group patients treated paliperidone...
Abstract Introduction Providing accurate, evidence-based information to women with Zika infection during pregnancy was problematic because of the high degree uncertainty in diagnosis and associated risk. The 2015-17 virus epidemic overwhelmingly affected countries limited access safe abortion. Understanding women’s perspectives on risk communication context an emerging pathogen can help inform response future outbreaks that affect fetal or child development. Methods We conducted a...