A5003383302- Dental Implant Techniques and Outcomes
- Periodontal Regeneration and Treatments
- Oral microbiology and periodontitis research
- Bone Tissue Engineering Materials
- Dental materials and restorations
- Dental Radiography and Imaging
- Oral and gingival health research
- Oral Health Pathology and Treatment
- dental development and anomalies
- Orthodontics and Dentofacial Orthopedics
- Oral and Maxillofacial Pathology
- Endodontics and Root Canal Treatments
- Bone and Dental Protein Studies
- biodegradable polymer synthesis and properties
- Salivary Gland Disorders and Functions
- Electrospun Nanofibers in Biomedical Applications
- HIV/AIDS oral health manifestations
- Orthopaedic implants and arthroplasty
- Reproductive tract infections research
- Systemic Sclerosis and Related Diseases
- Immune Response and Inflammation
- Biosensors and Analytical Detection
- Bone health and osteoporosis research
- Head and Neck Cancer Studies
- Antimicrobial Peptides and Activities
University of Campania "Luigi Vanvitelli"
2013-2024
University of Naples Federico II
2005-2017
Numerous pieces of evidence demonstrate that oxidative stress impairs biological functions, speeds up aging, and has a role in variety human diseases, including systemic oral inflammatory disorders, even cancer. Therefore, technologies providing accurate measures indicators or biomarkers appear essential the identification/prevention such their management. Particularly advantageous is employement point-of-care tests based on affordable small biochips since they can quickly process samples...
Background: The main therapeutic approach for periodontal diseases is mechanical treatment of root surfaces via scaling and planing (SRP). Multicenter clinical trials have demonstrated that the adjunctive use a chlorhexidine (CHX) chip effective in improving results compared to SRP alone. However, some recent studies failed confirm these results, conflicting were reported regarding effects CHX on subgingival microflora. aim this study was provide further data microbiologic chips when used as...
The regeneration of periodontal bone defects continues to be an essential therapeutic concern in dental biomaterials. Numerous biomaterials have been utilized this sector so far. However, the immune response and vascularity defect regions may disregarded when evaluating effectiveness for repair. Among several regenerative treatments, most recent technique situ tissue engineering stands out its ability replicate endogenous restorative processes by combining scaffold with particular growth...
The aim of the present study was to investigate accuracy a new digital impression system, comparing it plaster technique in realization full-arch implant-supported metal frameworks.We took 11 scans (8 upper maxilla and 3 lower jaw) on sample nine patients previously rehabilitated with fixed screw-retained prostheses following Columbus Bridge Protocol (CBP) four six implants (total: 51) since at least 4 months. Two impressions were taken for each dental arch: one analogic using pick-up...
The evaluation of salivary biomarkers has been proposed as a simple and non-invasive aid to the conventional periodontal diagnosis based on clinical-radiographic parameters. Matrix metalloproteinase-8 (MMP-8), especially in its active form, is considered one most reliable periodontitis, point-of-care tests (POCTs) have for clinical monitoring. In this proof-of-concept study, novel highly sensitive POCT plastic optical fiber (POF) biosensor exploiting surface plasmon resonance (SPR) detect...
Background: The aim of the present study was to assess additional clinical benefit autogenous cortical bone particulate (ACBP) when added enamel matrix derivative (EMD), compared EMD alone, in treatment deep periodontal intraosseous defects. Methods: A total 28 lesions 27 patients with advanced periodontitis were included this controlled trial and randomly assigned group (14 defects) or + ACBP defects). Immediately before surgery (baseline) after 6 12 months, probing depth (PD), attachment...
Surface treatment by argon plasma is widely used as the last step of manufacturing process titanium implant fixtures before their sterilization gamma rays. The possibility using such a technology in daily clinical practice particularly fascinating. aim present study was to assess effects on different surfaces previously exposed vitro bacterial contamination.Sterile c.p. discs with turned (T, Sa: 0.8μm), sandblasted/acid-etched (SAE, 1.3μm) and sprayed (TPS, 3.0μm) surface were this study. A...
The aim of the present randomized clinical trial (RCT) with a parallel arm design was to evaluate and microbiological efficacy repeated ICG-aPDT as an adjunct full-mouth subgingival debridement in treatment periodontitis.Twenty-four periodontitis patients were treated ultrasonic (FMUD). Initial sites probing depth (PD) > 4 mm randomly assigned receive test (ICG-aPDT 810 nm diode laser) or control (off-mode aPDT) one four weeks after FMUD. Clinical parameters registered 3 6 months. presence...
Among pro-inflammatory cytokines, Interleukin-1β is crucially involved in several inflammatory-based diseases and even cancer. Increased levels oral fluids have been proposed as an early marker of periodontitis, a broadly diffused chronic inflammatory condition periodontal-supporting tissues, leading eventually to tooth loss. We describe the development portable surface-plasmon-resonance-based optical fiber probe suitably coated with anti-Interleukin-1β antibody monolayer. A pico-nanomolar...
The analysis of salivary biomarkers as expression periodontal health conditions has been proposed a useful aid to conventional diagnostic approaches. In this study, we present point-of-care test (POCT) exploiting surface plasmon resonance (SPR)-based optical biosensor detect macrophage inflammatory protein (MIP)-1α, promising marker periodontitis. A plastic fiber (POF) was suitably modified and functionalized by an antibody self-assembled monolayer against MIP-1α for plasmonic detection....
Oral Squamous Cell Carcinoma (OSCC) shows an overall 5 yr survival rate of just above 50%. With estimated 390,000 new cases per year the current therapeutic approaches have failed in past 20 to improve survival. Reducing burden this malignancy represents a challenge for clinicians around globe. Early diagnosis most effective option reduce impact OSCC. Several chairside adjunctive techniques been researched early OSCC but many them found limited application due their low sensitivity and...
The aim of the present study was to examine behaviour human bone marrow-derived mesenchymal stem cells (BM-MSC) fluoride-modified grit-blasted (F-TiO) titanium surfaces compared with ones (TiO).Implant were analysed by atomic force microscopy (AFM) and scanning electron (SEM). BM-MSC isolated from healthy donors grown on implant surfaces. Cell adhesion proliferation, type I collagen (Col I) synthesis, osteoblastic differentiation (in terms alkaline phosphatase activity, osteocalcin synthesis...