Research Article| November 01 1964 Citrate and the conversion of carbohydrate into fat. A comparison citrate acetate incorporation fatty acids Spencer; Spencer Search for other works by this author on: This Site PubMed Google Scholar L Corman; Corman JM Lowenstein Biochem J (1964) 93 (2): 378–388. https://doi.org/10.1042/bj0930378 Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Facebook Twitter LinkedIn Email Cite Get Permissions Citation...

<h3>AIMS</h3> To analyse the results of intraocular pressure (IOP) reduction in refractory glaucoma following diode laser cyclophotocoagulation with a repeatable standard protocol. <h3>METHODS</h3> 58 eyes 53 patients were followed for 6–37 months (mean 19 months) after initial cyclodiode treatment. <h3>RESULTS</h3> Mean (SD) pretreatment IOP was 33.0 mm Hg (10.7) reducing at final index visit to 16.7 (7.8) (p&lt;0.0001). The mean antiglaucoma medication score per eye significantly reduced...

The HTA Programme was

To study the refractive status and corneal topography in Down's syndrome.A matched cohort subgroup of 50 individuals with syndrome Manchester area aged 15-22 years was studied by refraction, topography, A-scan biometry, slit lamp examination, orthoptic examination.(1) A linear relation found between axial length spherical equivalent refraction. There no statistical keratometry length. (2) 80% group had a hyperopic refraction (mean +2.46 D, range +0.5 to +7.5 D); 18% were myopic -2.75 -0.5...

Purpose To obtain consensus opinion for the development of a standards framework and implementation virtual clinics glaucoma monitoring in UK using modified Delphi methodology. Methods A technique was used that involved sampling members Glaucoma Eire Society (UKEGS). The first round scored strength agreement to series statements 9-point Likert scale. revised were subjected second scoring free-text comment. final discussed agreed by an expert panel consisting seven subspecialists from across...

Gastric biopsy specimens were taken in 33 patients before and after procedures to divert bile (construction of Roux loop 19, closure gastrojejunostomy 14). Each specimen was assessed for dysplasia, intestinal metaplasia, atrophy, gastritis, each variable being given a score ranging from 0 6. Patients preoperative postoperative scores these variables based on the average all or specimens. Comparison between histology showed that there no difference metaplasia. who underwent improvement...

Background Glaucoma referral filtering schemes have operated in the UK for many years. However, there is a paucity of data on false-negative (FN) rate. This study evaluated clinical effectiveness Manchester Enhanced Referral Scheme (GERS), estimating both false-positive (FP) and FN rates. Method Outcome were collected patients newly referred through GERS assessed ‘usual-care’ clinics to determine FP rate (referred subsequently discharged at their first visit). For rate, glaucoma suspects...

Glaucoma filtering schemes such as the Manchester Enhanced Referral Scheme (GERS) aim to reduce number of false positive cases referred Hospital Eye Services. Such can also have wider system benefits, they may waiting times for other patients. However, previous studies cost consequences and benefits glaucoma are inconclusive. We investigate GERS.Observational study.A analysis from perspective National Health Service (NHS) was conducted using audit data GERS.2405 patients passed through GERS...

Primary open angle glaucoma is the most prevalent type of and leading cause irreversible blindness worldwide. The genetic basis poorly understood. Of 14 loci associated with this disease, only two genes have been identified, accounting for approximately 4% cases. authors investigated primary in a large four-generation family an apparent autosomal dominant mode inheritance.Twenty-three members underwent comprehensive phenotyping by single ophthalmologist, MYOC gene was sequenced all affected...

Purpose: This study investigated the efficacy and safety of Baerveldt glaucoma implants (BGI) in adults with uveitic (UG) at Manchester Uveitis Clinic.Methods: was a retrospective 42 patients UG who underwent BGI implantation between 2006 2015. Primary outcome measures were intraocular pressure (IOP) reduction number medications 5-year follow-up. Three IOP success criteria chosen: 1.IOP ≤21 mmHg ≥20% from baseline 2.IOP ≤17 3.IOP ≤14 mmHg.Results: The mean pre-operative 29.5 ± 9.5 on 3.9...

AIMS--Two methods of indirect ophthalmoscopic estimation optic disc size, the 78 dioptre lens and biometer were evaluated. METHODS--Twenty nine eyes 29 patients measured by both compared with size calculated using three planimetric corrections described Bengtsson Krakau. RESULTS--The closest agreement clinical measurements was found correction 3. There a significant difference between D (p &lt; 0.0001) = 0.0027) results. also two 0.0001). Both showed acceptable intraobserver variation (CoV...

A knowledge of the optic disc size may be value when assessing glaucoma suspect. The vertical diameter was measured using a Zeiss four mirror gonioscope and 900 Haag-Streit slit-lamp in one eye 39 patients, 32 with refractive errors within 3 dioptres emmetropia. by projecting slit beam known height onto image disc. magnification factor for contact lens calculated from first principles recalculated. These measurements were compared those obtained photographic methods corrections suggested...

A graphical method was used to assess the effect on pupil shape and circumference of various flexible iris hook malpositions. Results confirmed that all malpositions necessitate increased stretching create space perform a capsulorhexis given diameter. This also addition fifth pentagonal reduces by 17%. simple marking limbus before insertion ensure equidistant separation thus minimize is suggested.

"She wouldn't remember. Even when I go through, and she's decided to bed, I'll say come do her drops. If didn't that, they be done." Dementia is widely considered as a key factor in whether patients take their medication prescribed. However, few studies have examined the effect of dementia on management strategies for glaucoma including how patient carer needs impact adherence long-term prognosis. We report findings from qualitative grounded theory study incorporating views patients, carers,...