A5053382578- Neurogenesis and neuroplasticity mechanisms
- Neuroscience and Neuropharmacology Research
- Olfactory and Sensory Function Studies
- Memory and Neural Mechanisms
- Nerve injury and regeneration
- Nicotinic Acetylcholine Receptors Study
- Transcranial Magnetic Stimulation Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Neural dynamics and brain function
- Advanced Neuroimaging Techniques and Applications
- Receptor Mechanisms and Signaling
- Growth Hormone and Insulin-like Growth Factors
- Ion channel regulation and function
- Neurological disorders and treatments
- Stress Responses and Cortisol
- Neuroscience and Neural Engineering
- Alzheimer's disease research and treatments
- Retinoids in leukemia and cellular processes
- Oropharyngeal Anatomy and Pathologies
- Tryptophan and brain disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Temporomandibular Joint Disorders
- Head and Neck Surgical Oncology
- Hemispheric Asymmetry in Neuroscience
Universidad de Salamanca
2001-2021
Instituto de Estudios de Ciencias de la Salud de Castilla y León
2000-2018
Instituto Cajal
1989-1996
Consejo Superior de Investigaciones Científicas
1992-1993
Instituto Ramón y Cajal de Investigación Sanitaria
1992
Abstract Autoradiographic and Golgi techniques are used to study the origin, developmental characteristics, adult morphology of cells sublayer VIb in somatosensory cortex rat. In rat, this forms a stratum two three rows located immediately above white matter. It is clearly separated from remaining cortical layers by light plexus fibers. The plate begins appear lateral wall brain hemisphere at embryonic day 15 (E15). By using tritiated thymidine autoradiography, we can see that generated...
Due to the absence of agreement about an effective unified treatment for temporomandibular disorders, non-invasive therapies such as EMG-biofeedback generate a greater interest. Furthermore, most studies present show methodological deficiencies that must be solved in future, which makes important emphasize this line studies.Fourteen patients were selected case series study, and replied questionnaire concerning awareness bruxism, painful muscles, muscle tension. They also practiced intraoral...
Intracellular recordings in slice preparations of the basolateral amygdala were used to test which excitatory amino acid receptors mediate postsynaptic potentials due stimulation external capsule. These also examine action muscarinic agonists on evoked potentials. from amygdaloid pyramidal neurons revealed that carbachol (2-20 microM) suppressed, a dose-dependent manner, responses by capsule (EC). This effect was blocked atropine. The estimated effective concentration produce half-maximal...
We previously demonstrated that the administration of GH immediately after severe motor cortex injury, in rats, followed by rehabilitation, improved functionality affected limb and reexpressed nestin contralateral cortex. Here, we analyze whether these effects depend on a time window injury reexpression actin. Injured animals were treated with (0.15 mg/kg/day) or vehicle, at days 7, 14, 35 cortical ablation. Rehabilitation was applied short long term (LTR) lesion then sacrificed. Nestin...
Abstract The medial septum/diagonal band region, which participates in learning and memory processes via its cholinergic GABAergic projection to the hippocampus, is one of structures affected by beta amyloid (βA) deposition Alzheimer's disease (AD). acute effects βA (25–35 1–40) on action potential generation glutamatergic synaptic transmission slices septal area rat brain were studied using current patch‐clamp techniques. mechanism through M1 muscarinic receptors voltage‐dependent calcium...
Lesions in specific areas of the rat motor cortex generate deficits related to fine movement performance affecting forelimb. We have previously shown that transplants embryonic frontal ameliorate these deficits. Amelioration has been associated with a functional integration transplant due connections established between host brain and graft. In current investigation, electrophysiological properties transplanted cells both intra-transplant adjacent are analyzed. For this purpose, adult rats...
Previously we demonstrated, in rats, that treatment with growth hormone (GH) and rehabilitation, carried out immediately after a motor cortical ablation, significantly improved the affectation produced by lesion induced re-expression of nestin contralateral cortex. Here analyze proliferation ablation frontal cortex investigate role striatum thalamus recovery. The rats were subjected to dominant hemisphere or sham-operated treated GH vehicle (V), for five days. At 1 dpi (days post-injury),...
Using an immunohistochemical technique, we have studied the distribution of kynuneric acid (KYNA) and 3-hydroxyanthranilic (3-HAA) in a rat brain injury model (trauma). The study was carried out inducing cerebral ablation frontal motor cortex. Two mouse monoclonal specific antibodies previously developed by our group directed against KYNA 3-HAA were used. In control animals (sham-operated), expression both not observed. which performed, highest number immunoreactive cells containing or...
Previously we demonstrated, in rats, that the treatment with growth hormone (GH) and rehabilitation, carried out immediately after a motor cortical ablation, significantly improved affectation produced by lesion induced re-expression of nestin contralateral cortex. Here analyze proliferation ablation frontal cortex investigate role striatum thalamus recovery. The rats were subjected to dominant hemisphere or sham-operated treated GH vehicle (V), for five days. At 1 dpi (days injury), 5...
We produced and characterized two monoclonal antibodies, termed 1.9.E 4.11.C, that specifically recognize olfactory bulb ensheathing glia. Both antibodies were generated using the nerve layer (ONL) of newborn rat bulbs (P0, P1) as immunogens. The specificity these was tested by immunofluorescence techniques on tissue sections cultures adult neonatal bulbs, Western blot analysis. labeled ONL glomerular (OB) rats. In rats, immunostained cells from peripheral fascicles. Furthermore, reacted...