A5016160845- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Monoclonal and Polyclonal Antibodies Research
- Bone health and osteoporosis research
- Systemic Sclerosis and Related Diseases
- Bone and Joint Diseases
- Vitamin D Research Studies
- Immunodeficiency and Autoimmune Disorders
- Inflammatory Myopathies and Dermatomyositis
- Bone health and treatments
- Inflammatory Bowel Disease
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Microscopic Colitis
- Peripheral Neuropathies and Disorders
- Musculoskeletal synovial abnormalities and treatments
- Sarcoidosis and Beryllium Toxicity Research
- Biosimilars and Bioanalytical Methods
- Chronic Lymphocytic Leukemia Research
- SARS-CoV-2 and COVID-19 Research
- Bone Metabolism and Diseases
- COVID-19 Clinical Research Studies
- Infectious Diseases and Tuberculosis
Hospital de São João
2019-2024
Universidade do Porto
2024
Centro Hospitalar de Vila Nova de Gaia
2022
Hospital Braga
2022
Centro Universitário de João Pessoa
2021
Center for Rheumatology
2020
To identify risk factors for SARS-CoV-2 infection and severe/critical COVID-19, to assess the humoral response after COVID-19 in these patients.
Background: Osteoporosis is commonly seen in patients with Systemic Lupus Erythematosus (SLE), even pre-menopausal patients. The etiology multifactorial and chronic glucocorticoid therapy seems to play a central role. Objectives: To investigate the ten-year risk of fracture assessed by Fracture Risk Assessment Tool (FRAX), without dual-energy X-ray absorptiometry (DXA) determine possible demographic or clinical factors associated an increased SLE population. Methods: Retrospective study...
<h3>Background:</h3> Anti-tumor necrosis factor-α (anti-TNF) therapy is often part of the treatment strategy for rheumatic diseases (RD) and inflammatory bowel disease (IBD). An association between anti-TNF agents development lupus erythematosus (LE)-like syndrome has been established some patients may have a definitive diagnosis systemic (SLE), requiring appropriate treatment. To date, no studies conducted to analyze follow-up IBD who developed LE-like induced by agents....
Synovial chondromatosis is a proliferative disease of the synovium associated with cartilage metaplasia that causes localized joint pain and affects its function. A 63-year-old white woman presented right hip pain, lasting over 10 years. Pelvic radiography showed osteoarthritis ipsilateral periacetabular opacities. Computed tomography confirmed diagnosis synovial chondromatosis. benign, rare condition joints characterized by presence free cartilaginous bodies within capsule. Although...
This study aimed to identify the rheumatoid arthritis (RA) patients under biological therapy who have FRAX® scores classified as high fracture risk and evaluate if they are receiving treatment for osteoporosis (OP). The authors also investigated intra-individual agreement between calculated with without bone mineral density (BMD).A single-center retrospective cohort was performed in a total of 303 RA biologics. Demographic clinical data were collected using Rheumatic Diseases Portuguese...
<h3>Background</h3> Interleukin 6 (IL-6) plays a role on B cell differentiation and antibody production. However, few information is available considering the effect of tocilizumab (TCZ) rheumatoid factor (RF) anti-citrullinated protein antibodies (ACPAs) levels in Rheumatoid Arthritis. <h3>Objectives</h3> To compare serum RF ACPAs RA patients at beginning therapy with TCZ 12 months under TCZ, assessing if its variations correlate several disease activity scores. <h3>Methods</h3>...
Background: Musculoskeletal symptoms represent the most common extraintestinal manifestations of inflammatory bowel disease (IBD) and a major cause impaired quality life in these patients. Spondyloarthritis (SpA) is classically associated with IBD, but other rheumatic may occur. Objectives: To characterize musculoskeletal diseases an IBD cohort. Methods: Retrospective monocentric descriptive study including all patients consecutively reffered from Gastroenterology to Rheumatology Department...
<h3>Background:</h3> Elderly population with rheumatoid arthritis (RA) is increasing. However, these patients are frequently excluded from clinical trials and data on effectiveness safety of biologic Disease-Modifying Antirheumatic Drug (bDMARD) scarce. <h3>Objectives:</h3> To assess the persistence 1<sup>st</sup> bDMARD among elderly (≥65 years). <h3>Methods:</h3> Prospective multicenter cohort-study RA starting a registered at Reuma.pt. Demographic disease characteristics, comorbidities,...
<h3>Background</h3> Recently, systemic inflammation has been shown to be a key determinant of prognosis. Neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte (MLR), and platelet-lymphocyte (PLR) related status suggested as additional markers response bDMARDs in patients with rheumatoid arthritis. However, few studies were yet developed about this subject psoriatic arthritis (PsA). <h3>Objectives</h3> The aim study was investigate the time-course change NLR, MLR PLR levels PsA after 6 12...
Background: Spinal mobility is assessed frequently in patients with psoriatic arthritis (PsA) using Bath Ankylosing Spondylitis Metrology Index (BASMI) to provide baseline measurement, monitor changes over time and assess the impact of clinical interventions. BASMI comprises 4 measures spinal (cervical rotation, tragus-to-wall distance, modified Schober’s test lumbar lateral flexion) one hip measurement (intermalleolar distance). Objectives: The aim this study investigate time-course change...
Background: Low bone mineral density (BMD) is common in ankylosing spondylitis (AS). The fracture risk (FR) increased and its reduction with pharmacologic therapy not clearly defined this population. However, early screening bisphosphonates as first-line treatment are recommended. Objectives: To investigate the influence of dual-energy X-ray absorptiometry (DXA) ten-year assessed by FR Assessment Tool (FRAX) to determine possible demographic or clinical factors associated an a...
Background: Few studies have evaluated the prevalence and treatment of osteoporosis (OP) in patients with psoriatic arthritis (PsA), many these are not screened using dual-energy X-ray absorptiometry (DXA). FRAX makes it possible to stratify risk define which may benefit from anti-osteoporotic treatment, but its usefulness this population is well established. Objectives: The aim study was determine whether application changes indication for PsA patients, according Portuguese guidelines....
Background: Patients with rheumatoid arthritis (RA) have a higher risk of osteoporosis not only due to chronic inflammation status, but also the treatment glucocorticoids. FRAX is computer-based algorithm developed by World Health Organization for estimation 10-year hip or major osteoporotic fracture. Inclusion femoral neck bone mineral density (BMD) in optional. Objectives: The study aimed identify RA patients under biological disease-modifying antirheumatic drug (bDMARD), who scores,...