A5017614125- Phytochemicals and Antioxidant Activities
- Phytochemistry and Biological Activities
- Pharmacology and Obesity Treatment
- Natural Antidiabetic Agents Studies
- Essential Oils and Antimicrobial Activity
- Cynara cardunculus studies
- Antioxidant Activity and Oxidative Stress
- Genomics, phytochemicals, and oxidative stress
- Enzyme Catalysis and Immobilization
- Microbial Metabolism and Applications
- Morinda citrifolia extract uses
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Bioactive Compounds
- Bee Products Chemical Analysis
- Diet, Metabolism, and Disease
- Muscle metabolism and nutrition
- Agriculture, Plant Science, Crop Management
- Phytochemical and Pharmacological Studies
- Plant-based Medicinal Research
- Liver Disease Diagnosis and Treatment
- Phytochemistry Medicinal Plant Applications
- Postharvest Quality and Shelf Life Management
- Medicinal Plant Extracts Effects
- Toxin Mechanisms and Immunotoxins
- Antimicrobial Resistance in Staphylococcus
Lodz University of Technology
2006-2021
University of Łódź
2006-2018
Dietary inhibitors of fats and carbohydrates degrading enzymes can reduce obesity type 2 diabetes. In this study, we screened crude extracts from 30 commonly consumed fruits to test their in vitro inhibitory effect against key relevant for (pancreatic lipase) diabetes (α-glucosidase α-amylase), total phenolic content (Folin-Ciocalteu method), antioxidant capacity (ABTS FRAP). The IC50 values the tested varied 39.91 >400 mg/mL, 1.04 >80 0.72 135.07 mg/mL α-glucosidase, α-amylase, pancreatic...
Summary This study has evaluated the antioxidant capacity and content of both water‐ lipid‐soluble antioxidants present in red white cabbages, savoy cabbage Brussels sprouts. Total phenolic vitamin C contents varied from 21 to 171 mg per 100 g 18 129 g, respectively. Levels carotenoids ranged 0.009 1.16 while α ‐tocopherol levels 0.008 0.82 g. Red sprouts were most rich sources dietary antioxidants, their was lowest cabbage. Water‐soluble main compounds vegetables tested, contribution trolox...
Red cabbage is, among different vegetables, one of the major sources anthocyanins. In present study an in vitro digestion method has been used to assay influence physiological conditions stomach and small intestine, as well faecal microflora on anthocyanins stability red anthocyanin-rich extract. The recovery during gastrointestinal was strongly influenced by food matrix. results showed that other constituents enhanced digestion. amount (HPLC method) antioxidant capacity (ABTS FRAP assays)...
Propolis-based therapeutic agents represent this potential for the development of new drugs in dental care. The aim a clinical-cohort study was to determine influence application toothpaste enriched with Brazilian extract propolis (EEP) on health status oral cavity. Laboratory analysis conducted order assess chemical composition EEP including total phenolic compounds, DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity, ABTS cation and FRAP assay. Clinical research involved two...
Summary The contents of vitamin C, total phenolics, anthocyanins, hydroxybenzoic and hydroxycinnamic acids as well 2,2′‐azinobis‐(3‐ethylbenzothiazoline‐6‐sulfonic acid) monocation radical scavenging activity were evaluated in two varieties red cabbage before after conventional steam‐cooking. During the cooking 32.7–64.5% C 45.7–66.9% phenolics retained cooked tissue. Decreasing water volume by half led to better retention both (by 2.7–14.5%) 14.2–18.4%). However, shortening time affected...
Type 2 diabetes mellitus, which is usually a result of wrong dietary habits and reduced physical activity, represents 85-95% all cases among other diet related diseases the major cause deaths. The disease characterized mainly by hyperglycemia, associated with attenuated insulin sensitivity or beta cells dysfunction caused multiple stimuli, including oxidative stress loss secretion. Since polyphenols possess biological activities constitute an important part human diet, they have recently...
The toxicity of in vitro tested compounds is usually evaluated based on AC50 values calculated from dose-response curves. However, there a large group for which standard four-parametric sigmoid curve fitting may be inappropriate estimating AC50. In the present study, 22 polyphenol-rich were prioritized least to most toxic total area under and over curves (AUOC) relation baselines. studied ranked across three key cell indicators (mitochondrial membrane potential, integrity nuclear size) panel...
Inhibition of digestive lipases refers to the suppression dietary fat absorption and, some extent, a strategy against overweight and obesity. In this study, effect five commercial black chokeberry juices on pancreatic lipase as key enzyme relevant obesity was investigated using substrates triolein, sunflower oil, rapeseed oil emulsions well 4-methylumbelliferyl oleate. The were also analyzed for antioxidant capacity (ABTS·+, DPPH·, FRAP methods), qualitative quantitative composition phenolic...
Due to constantly increasing antibiotic resistance of pathogens and participation the biofilms they make in various types infections, a development alternative therapeutic strategies becomes an urgent need. Taking advantage biological activity plant-derived compounds can solve this problem. In study antimicrobial, including those synergistic with classic antibiotics, cytotoxic properties newly-obtained extracts from Vaccinium myrtillus leaves (VLE) Frangula alnus bark (FBE) were evaluated....
Abstract The aim of the present study was to evaluate whether blackcurrant leaf extract (BLE) modulates endothelium antithrombotic function, namely increases expression/activity ADPase (CD39) and augments production nitric oxide in human umbilical vein endothelial cells (HUVEC). It found that BLE with proanthocyanidins (60 % total polyphenol content) increased CD39-positive cell fraction (up 10 for 2.5 μg/ml, up 33 15 p < 0.05 or less) a concentration-dependent manner, enhanced synthase...
The objective was an assessment of the impact Leonurus cardiaca L. extract (LCE) and ursolic acid (UA) on adhesive properties Staphylococus aureus NCTC 8325 strain, expressing virulence factors important in pathogenesis infective endocarditis. adhesion biofilm formation bacteria cultured presence subinhibitory concentrations LCE or UA abiotic surface covered with fibrinogen, fibronectin collagen, were evaluated. Inhibitory effects staphylococcal adherence to both types demonstrated. This,...
The immunomodulatory activity of Leonurus cardiaca L. polyphenol-rich extract (LCE) was tested in vitro on HUVECs to explore its potential therapeutic usefulness the treatment inflammatory lesions. phytochemical composition LCE, antioxidant and cytotoxic activity, influence LCE NO platelet-activating factor (PAF) secretion by platelet aggregation were all assessed. Total polyphenol contents reached 137.0 ± 0.8 mg/g, with hydroxycinnamic acid derivatives as predominant phenolic compounds....
In the present study, an in vitro digestion method has been used to assay influence of physiological conditions mouth, stomach, and intestine on stability activity different cell models main phenolic compounds from Viburnum opulus fresh juice (FJ), phenolic-rich (PJ), bioavailable fractions (DFJ DPJ). The data obtained indicate that V. samples achieved after had cellular glucose lipid metabolism. fraction both digested juices stimulated uptake decreased accumulation by L6 myoblasts HepG2...
Introduction. Cranberrybush (Viburnum opulus L.) is a plant rich in phenols. Chlorogenic acid main compound responsible for its antioxidant activity. This also has antibacterial and anti-inflammatory properties, this reason it used prevention, as well the treatment of many diseases, mainly those genitourinary tract, but heart or lungs. So far, there are few studies that suggest V. anti-cancer activity could become supplement such therapies. Aim. The aim study was to assess compare effect...