A5006640716- Virology and Viral Diseases
- Herpesvirus Infections and Treatments
- Animal Disease Management and Epidemiology
- Poxvirus research and outbreaks
- Zoonotic diseases and public health
- Viral Infections and Vectors
- Viral gastroenteritis research and epidemiology
- Microbial infections and disease research
- Animal Virus Infections Studies
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- Vector-Borne Animal Diseases
- Virus-based gene therapy research
- Effects of Environmental Stressors on Livestock
- Venomous Animal Envenomation and Studies
- COVID-19 epidemiological studies
- Biochemical effects in animals
- Viral Infections and Outbreaks Research
- Meat and Animal Product Quality
- Bacteriophages and microbial interactions
- RNA regulation and disease
- Hepatitis B Virus Studies
- Viral Infections and Immunology Research
- Livestock Management and Performance Improvement
- Transgenic Plants and Applications
National Veterinary Research Institute
2012-2024
Friedrich-Loeffler-Institut
2020
Forestry Research Institute of Nigeria
2020
Lumpy skin disease virus (LSDV), together with sheeppox and goatpox virus, belong to the genus Capripoxvirus within family Poxviridae. Collectively, they are considered most serious poxvirus diseases of agricultural livestock. Due their severe clinical course consequent loss production, as well high mortality naïve small large ruminant populations, known have a significant impact on economy global trade restrictions affected countries. Therefore, all capripox classified notifiable under...
Anthropogenic exposure of domestic animals, as well wildlife, can result in zoonotic transmission events with known and unknown pathogens including sarbecoviruses. During the COVID-19 pandemic, SARS-CoV-2 infections most likely resulting from spill-over humans, have been documented worldwide. However, only limited information is available for Africa. The anthropozoonotic humans to followed by further inter- intraspecies propagation may contribute viral evolution, thereby subsequently alter...
Marek's disease (MD) and chicken infectious anaemia (CIA) are viral immunosuppressive diseases of poultry caused by the MD virus (MDV) CIA (CIAV) respectively. Despite vaccination against MD, incidence in vaccinated flocks Nigeria persists. However, underlying factors like co-infection with CIAV have not been investigated country. This study was designed to investigate possible co-infections MDV Nigeria. In 2016, tumorous tissue samples were collected from suspected cases at necropsy Jos,...
This study unveils immunodominant epitopes from the African Swine Fever Virus Major Capsid protein and created a multiepitope vaccine candidate. Protein sequences of 42 strains ASFV 28 countries were selected. Binding to MHC proteins predicted. T Linear B Lymphocytes adopted evaluated for antigenicity, immunogenicity, allergenicity, toxicity. Selected modelled molecularly docked against appropriate proteins. An adjuvant multiple linkers used create candidate (VC). After evaluating...
Abstract Peste‐des‐petits‐ruminants (PPR) and Goat pox (GTP) are two devastating economically important transboundary animal diseases of small ruminants in Africa Asia that have been difficult to control. This study however, investigated an outbreak PPR GTP a mixed flock indigenous sheep goats Kanam, North Central Nigeria. A total nine sera seven tissues (lungs, spleen, scab skin) samples were collected analysed the laboratory using competitive enzyme linked immunosorbent assay (cELISA) for...
Lumpy Skin disease (LSD) is an economically important in cattle caused by the LSD virus (LSDV) of genus Capripoxvirus, while pseudocowpox (PCP) a widely distributed zoonotic PCP (PCPV) Parapoxvirus. Though both viral pox infections are reportedly present Nigeria, similarities their clinical presentation and limited access to laboratories often lead misdiagnosis field. This study investigated suspected outbreaks organized transhumance herds Nigeria 2020. A total 42 scab/skin biopsy samples...
humidity (RH) were measured concurrently with the RT. The AT and RH values ranged between 23.5 39.0°C 43 - 97% respectively. outside thermo-neutral zone for pig, indicating that season was thermally stressful. values, which fluctuated hour of day increased journey, significantly (P 0.05) corresponding value 39.4 ± 0.3°C in control pigs, demonstrating AA did not induce hypothermia experimental pigs. In conclusion, transportation pigs by road 8 h induces hyperthermia administration...
In this present study, bacteria were isolated from soil obtained oil contaminated mechanic site in Enugu. Out of the 206 forming colonies, 16 colonies selected based on observable morphological differences and screened for crude degraders. isolates, 11 isolates assumed to be degraders because they formed maximum clear zones mineral salt media. At end 14 days incubation, out degraded ranging 5% 60%. Isolate 1, 5 had highest percentage degradation 60%, followed by isolate 13 with 50%...
Viral skin diseases namely lumpy disease (LSD), bovine papilloma (BP), goat pox (GTP) and contagious ecthyma (CE) have been reported in Plateau State, but our search through literatures did not reveal any documented prevalence rates of these diseases. A retrospective study LSD, BP, GTP CE was carried out based on Jos abattoir (2005-2016) laboratory records National Veterinary Research Institute, Vom, Nigeria (2010-2016). Based the Abattoir records, were as follows LSD: 0.13% BP 0.5% Cattle....
Developing vaccine stabilizers from local natural sources is desirable especially if the stabilizer would enhance ability of antigen to withstand frequent failures in cold chains. The study was undertaken formulate immunogenic live Newcastle Disease (ND) LaSota vaccines stabilized with modified native starches for use at and ambient temperatures assess immunogenicity starch vaccinated chickens. Native extracted tubers Plectranthus esculentus (Family, Lamiaceae) by carboxymethylation...
West Nile Virus (WNV) is a zoonotic mosquito borne arbovirus that causes encephalitis in horses and human. It pathogen of public health importance globally. Data on WNV epizootics Nigeria limited, necessitating seroprevalence studies animals. In this study, 118 sera from Polo 66 archival 31 horses, 10 chicken, 15 rabbits dogs Northern South-Western were screened for using multi-species competitive ELISA. The overall was 78.26% (n=144). 93.28% (n=139) the 149 horse positive, all chicken...
Aim: This research sought to experiment on a cheaper alternative snake antivenom production using hyperimmunized chicken eggs. Methods: Twenty-two Swiss albino mice were used determine the median lethal dose (LD50) and lethality neutralization assay. Twenty-layer chickens, aged 17-weeks-old divided into two groups of 10 chickens each. Based body weight, group A with 1/5th LD50 crude Bitis arietans venom in adjuvant (Montanide™ ISA 201) at two-weeks interval over eight-weeks period; while B...
For many decades, small-scale livestock, including rabbit production, has been a veritable pro-poor poverty alleviation venture in Africa. With the rising population and increasing demand for food, need to introduce expand farms long-term sustainability cannot be overemphasized. While production commercialization of domestic is desirable, intensification livestock also comes with some animal health problems. One these emergence Rabbit Haemorrhagic Disease (RHD) caused by Virus (RHDV). The...
Knowledge is crucial for improving animal welfare. People's perceptions, attitudes, and understanding may be a hindrance to adopting welfare-improving ideas which developing effective welfare policies advocacy in Nigeria. This study evaluates the current knowledge, perceptions of among Nigerian residents. A cross-sectional survey using structured questionnaire distributed via emails, social media platforms, by personal contact. The collected data from 694 respondents across 36 states Federal...
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The COVID-19 pandemic has caused the death of 7.1 million people worldwide as 7 July 2024. In Nigeria, first confirmed case was reported on 27 February 2020, subsequently followed by a nationwide spread SARS-CoV-2 with morbidity and mortality reaching 267 173 3155, respectively, At beginning pandemic, only few public health laboratories in Nigeria had capacity for molecular diagnosis. National Veterinary Research Institute (NVRI), already experienced influenza diagnosis, responded to...
Bovine spongiform encephalopathy (BSE), popularly known as ‘mad cow disease’, led to an epidemic in Europe that peaked the mid-1990s. Its impact on developing countries, such Nigeria, has not been fully established information livestock and surveillance eluded those charge of this task. The BSE risk Nigeria’s cattle population currently remains undetermined, which resulted international trade restrictions commodities from population. This is mainly because a lack updated assessments disease...
Outbreaks of contagious ecthyma (CE) are frequently reported in sheep and goat flocks Nigeria with severe clinical outcomes. CE is a debilitating economically important disease primarily affecting goats caused by the Orf virus (ORFV). Despite field reports country, there no concise country-wide epidemiological data on limited genetic circulating Nigerian ORFV available public domain.An survey molecular characterization from 2014 to 2016.Data were collected using designed questionnaires,...
Abstract Background Newcastle disease is a devastating in poultry caused by virulent virus (NDV), paramyxovirus endemic many regions of the world despite intensive vaccination. Phylogenetic analyses reveal ongoing evolution predominant circulating genotype 2.VII, and relevance potential antigenic drift under discussion. To investigate variation within neutralization-sensitive epitopes protein responsible for receptor binding, i.e. Hemagglutinin-Neuraminidase (HN) spike protein, we were...
Highly pathogenic avian influenza virus (HPAIV) belongs to the Orthomyxoviridae family and causes a systemic highly lethal disease in poultry. Vaccination with recombinant Newcastle vector viruses (NDV) expressing hemagglutinin (HA) of HPAIV H5N1 induces high antibody titers chickens free specific pathogens, conveying protection against infection H5N1. Protection possessing maternally derived NDV immunity was achieved after replacement surface proteins NDV, fusion protein (F),...