Haseena Khan

ORCID: 0000-0003-4643-4106
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About
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Research Areas
  • Seed and Plant Biochemistry
  • Plant tissue culture and regeneration
  • Plant-Microbe Interactions and Immunity
  • Food composition and properties
  • Microbial Metabolites in Food Biotechnology
  • Genetic and Environmental Crop Studies
  • Plant Pathogens and Fungal Diseases
  • Plant Molecular Biology Research
  • Nematode management and characterization studies
  • Microbial Natural Products and Biosynthesis
  • Genomics and Phylogenetic Studies
  • Hypothalamic control of reproductive hormones
  • Transgenic Plants and Applications
  • Wheat and Barley Genetics and Pathology
  • Biofuel production and bioconversion
  • Iron Metabolism and Disorders
  • Plant Pathogens and Resistance
  • CRISPR and Genetic Engineering
  • Genetics and Plant Breeding
  • Machine Learning in Bioinformatics
  • Food Allergy and Anaphylaxis Research
  • Photosynthetic Processes and Mechanisms
  • Chromosomal and Genetic Variations
  • Genetic Mapping and Diversity in Plants and Animals
  • Sperm and Testicular Function

University of Dhaka
2015-2024

University of Swabi
2024

University of Swat
2023

University of the Punjab
2021

Australian National University
2017-2020

Hazara University
2020

Gandhara University
2012

University of Peshawar
2011-2012

University of Benin
2011

Bangladesh Rice Research Institute
2002

Abstract Jute ( Corchorus sp.) is one of the most important sources natural fibre, covering ∼80% global bast fibre production 1 . Only olitorius and capsularis are commercially cultivated, though there more than 100 species 2 in Malvaceae family. Here we describe high-quality draft genomes these two their comparisons at functional genomics level to support tailor-designed breeding. The assemblies cover 91.6% 82.2% estimated genome sizes for C. , respectively. In total, 37,031 30,096 genes...

10.1038/nplants.2016.223 article EN cc-by Nature Plants 2017-01-30

Purpose: To investigate the heavy metals present in branded Pakistani herbal medicines used management of various human ailments.Method: The dosage forms assessed were tablets, capsules and syrups. samples prepared for analysis by wet digestion method using nitric acid perchloric treatment then analyzed a flame atomic absorption spectrometer.Results: Most products exceeded permissible limits lead (100 %), cadmium (68 chromium (96 %) nickel %). However, contents copper, manganese, zinc iron...

10.4314/tjpr.v10i4.16 article EN cc-by Tropical Journal of Pharmaceutical Research 2011-09-14

Grammothele lineata, an endophyte isolated in our laboratory from jute (Corchorus olitorius acc. 2015) was found to be a substantial paclitaxel producer. Taxol and its related compounds, produced by this were extracted growing the fungus simple nutrient media (potato dextrose broth, PDB). identified characterized different analytical techniques (TLC, HPLC, FTIR, LC-ESI-MS/MS) following extraction ethyl acetate. In PDB media, produce 382.2 μgL-1 of taxol which is about 7.6 x103 fold higher...

10.1371/journal.pone.0178612 article EN cc-by PLoS ONE 2017-06-21

The role of conserved nucleotides in nitrogen-fixation promoter function has been examined using both oligonucleotide and chemical mutagenesis to introduce base changes the Klebsiella pneumoniae nifL nifH promoters. Among ten mutations analysed, including six spontaneous mutations, at -12, -13, -14, -26, located previously identified sequences, perturbed activity promoters, demonstrating that these sequences are required for transcription. Not all produced similar strong down phenotypes when...

10.1093/nar/13.21.7621 article EN Nucleic Acids Research 1985-01-01

The endophytic bacterium Burkholderia contaminans NZ was isolated from jute, which is an important fiber-producing plant. This exhibits significant growth promotion activity in vivo pot experiments, and like other plant growth-promoting (PGP) bacteria fixes nitrogen, produces indole acetic acid (IAA), siderophore, 1-aminocyclopropane-1-carboxylate (ACC) deaminase activity. B . considered to exert a promising inhibitory effect on Macrophomina phaseolina , phytopathogen responsible for...

10.1371/journal.pone.0257863 article EN cc-by PLoS ONE 2021-09-30

The human gut, a dynamic and diverse ecosystem of trillions microorganisms, plays an essential role in the host's health disease. This review explores influence lifestyle choices like diet, stress, physical activity, environmental factors on gut microbiome their broader societal implications. Studies have reported that plant-based Mediterranean diets enhance microbial diversity. At same time, sedentary lifestyle, chronic processed foods, alcohol consumption badly impact composition lead to...

10.54393/fbt.v5i1.155 article EN Futuristic Biotechnology 2025-03-31

Abstract Lignin, a cross-linked macromolecule of hydrophobic aromatic structure, provides additional rigidity to plant cell wall. Although it is an integral part the cell, presence lignin considerably reduces quality fiber fiber-yielding plants. Decreasing in such plants holds significant commercial and environmental potential. This study aimed at reducing content jute-a crop, by introducing hpRNA-based vectors for downregulation two monolignoid biosynthetic genes- cinnamate 4-hydroxylase (...

10.1038/srep39984 article EN cc-by Scientific Reports 2017-01-04

Abstract Here we report a jute endophyte Staphylococcus hominis strain MBL_AB63 isolated from seeds which showed promising antimicrobial activity against aureus SG511 when screening for substances. The whole genome sequence of this strain, annotated using BAGEL4 and antiSMASH 5.0 to predict the gene clusters substances identified novel peptide cluster that belongs class I lantibiotic group. predicted (homicorcin) was found be 82% similar reported epicidin 280 having difference seven amino...

10.1038/s41598-021-90613-9 article EN cc-by Scientific Reports 2021-05-27

Abstract Immunization of proven fertile adult male monkeys (n = 3) with a recombinant FSH receptor protein preparation (oFSHR-P) (representing amino acids 1–134 the extracellular domain Mr∼ 15KDa) resulted in production blocking antibodies. The ability antibody to bind particulate and receptors intact granulosa cells was markedly (by 30–80%) inhibited by FSH. Serum T levels LH function following immunization remained unchanged. immunized showed 50% reduction (p< 0.001) transformation...

10.1210/endo.138.7.5381 article EN Endocrinology 1997-07-01

Pituitary follitropin (FSH) has pleiotropic actions on gonads, but it is not certain if all these events are mediated by a single receptor. A gene for the FSH receptor undergoes extensive alternate splicing generating multiple transcripts, and several of have been cloned characterized from sheep testis. In this study we investigated expression in HEK (human embryonic kidney) 293 cells cDNA encoding first eight exons along with carboxyterminal extension that contributed hypothetical...

10.1002/(sici)1098-2795(199712)48:4<471::aid-mrd7>3.0.co;2-n article EN Molecular Reproduction and Development 1997-12-01

The genotype characteristic of cultivars was investigated, along with varieties both the jute species, Corchorus olitorius and capsularis, in germplasm collection at Bangladesh Jute Research Institute (BJRI). DNA fingerprinting generated for 9 different 12 accessions by using random amplified polymorphic DNA(RAPD). A total 29 arbitrary oligonucleotide primers were screened. Seven gave polymorphism within varieties, 6 detected that tested. dendrogram engendered from these data, this a...

10.5483/bmbrep.2002.35.4.414 article EN BMB Reports 2002-07-31

The genetic factors that contribute to the development of coronary artery disease (CAD) are poorly understood. It is likely multiple genes act independently or synergistically CAD and outcome. Recently, an insertion/deletion (I/D) polymorphism human angiotensin I-converting enzyme (ACE) gene, a major component renin-angiotensin system (RAS), was identified. association ACE gene D allele with essential hypertension has been reported in African-American, Chinese, Japanese populations. However,...

10.5483/bmbrep.2002.35.3.251 article EN BMB Reports 2002-05-31

Abstract Background Eukaryotic promoter prediction using computational analysis techniques is one of the most difficult jobs in genomics that essential for constructing and understanding genetic regulatory networks. The increased availability sequence data various eukaryotic organisms recent years has necessitated better tools promoters sequences. Many methods have been developed to date but they yet provide acceptable predictive performance. One obvious criteria improve on current devise a...

10.1186/1471-2105-9-414 article EN cc-by BMC Bioinformatics 2008-10-04

Abstract The silver pride of Bangladesh, migratory shad, Tenualosa ilisha (Hilsa), makes the highest contribution to total fish production Bangladesh. Despite its noteworthy contribution, a well-annotated transcriptome data is not available. Here we report transcriptomic catalog Hilsa, constructed by assembling RNA-Seq reads from different tissues including brain, gill, kidney, liver, and muscle. Hilsa were collected aquatic habitats (fresh, brackish, sea water) sequencing was performed in...

10.1038/s41597-023-02132-z article EN cc-by Scientific Data 2023-04-17

Two of the most widely and intensively cultivated jute species, Corchorus capsularis olitorius, suffer severely from a stem rot disease caused by fungus Macrophomina phaseolina. Wild C. trilocularis, shows resistance to this pathogenic fungus. In study, technique differential display was applied identify genes which are differentially expressed, under both infected un-infected conditions, between trilocularis olitorius var O-72. xyloglucan endotransglycosylase/hydrolase (XTH) designated...

10.4161/cib.21422 article EN cc-by-nc Communicative & Integrative Biology 2012-11-01

There is an urgent need for developing crops with greater tolerance to environmental stresses. This even more important fiber crops, which are being pushed the marginal low-productive lands in order make room food crops. Jute source of a highly versatile and environmentally friendly natural fiber, second only cotton terms production variety uses. In this study, we used tissue culture independent method introducing CMV 35S promoter driven katE gene from Escherichia coli K12 into popular jute...

10.3906/biy-1205-52 article EN TURKISH JOURNAL OF BIOLOGY 2013-01-01

During the molecular cloning of ovine testicular follicle-stimulating (FSH) receptor that couples to Gs-type effector systems, we discovered novel cDNA clones were highly homologous. Some these contained an insert 1,584 bp, which consisted a divergent 3′ region spliced with 5′ was identical nucleotides 724–1,924, forming part 9th and 10th exons, coding FSH gene. The prominence alternately clone, suggested important functional implications, prompted this detailed investigation. Screening...

10.1002/(sici)1098-2795(199712)48:4<458::aid-mrd6>3.0.co;2-p article EN Molecular Reproduction and Development 1997-12-01
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