Eye movements can be used as alternative inputs for human-computer interface (HCI) systems such virtual or augmented reality well new communication ways patients with locked-in syndrome. In this study, we developed a real-time electrooculogram (EOG)-based eye-writing recognition system, which users write predefined symbolic patterns their volitional eye movements. For the “eye-writing” recognition, proposed system first reconstructs eye-written traces from EOG waveforms in real-time; then,...

Emotional sensitivity and impulsivity could cause interpersonal conflicts neuropsychiatric problems. Serotonin is correlated with behavioral inhibition impulsivity. This study evaluated whether the loudness dependence of auditory evoked potential (LDAEP), a biological marker central serotonergic activity, reflect emotional A total 157 healthy individuals were recruited, who performed LDAEP Go/Nogo paradigms during electroencephalogram measurement. Barratt scale (BIS), Conners' Adult ADHD...

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Objectives: Due to the absence of objective diagnostic criteria, tinnitus diagnosis primarily relies on subjective assessments. However, its neuropathological features can be objectively quantified using electroencephalography (EEG). Despite existing research, pathophysiology remains unclear. The this study was gain a deeper comprehension neural mechanisms underlying through comparison cognitive event-related potentials in patients with and healthy controls (HCs). Furthermore, we explored...

Abnormalities in the 40-Hz auditory steady-state response (ASSR) of gamma range have been reported schizophrenia (SZ) and are regarded as important pathophysiological features. Many previous studies diminished oscillations SZ, although some increased spontaneous oscillations. Furthermore, brain morphological correlates band ASSR deficits rarely examined. We investigated different measures their association with volumes psychological SZ. The was measured for 80 dB click sounds (1 ms, 500-ms...

Based on the constant associations made between major depressive disorder (MDD) and alpha asymmetry, MDD suicide, this study aimed to examine relationship frontal asymmetry suicide in patients.Sixty-six patients, of whom fifteen were male fifty-one female, recruited. Independent groups created based median score asymmetry: left dominant (LD) group right (RD) group. The band (8‒12 Hz) its sub-bands (i.e., low band: 8‒10 Hz; high 10‒12 interest. Source level was calculated as well.Suicidal...

Abstract The perception of opportunities and threats in complex visual scenes represents one the main functions human system. underlying neurophysiology is often studied by having observers view pictures varying affective content. It has been shown that viewing emotionally engaging, compared with neutral, (1) heightens blood flow limbic, frontoparietal, anterior structures (2) enhances late positive event-related potential (LPP). role retinotopic cortex this process has, however,...

Abstract Relatively little is investigated regarding the neurophysiology of adult attention-deficit/hyperactivity disorder (ADHD). Mismatch negativity (MMN) an event-related potential component representing pre-attentive auditory processing, which closely associated with cognitive status. We MMN features as biomarkers to classify drug-naive patients ADHD and healthy controls (HCs). Sensor-level (amplitude latency) source-level (source activation) were compared between electroencephalograms...

Mismatch negativity (MMN) is a measure of automatic neurophysiological brain processes for detecting unexpected sensory stimuli. This study investigated MMN reduction in patients with schizophrenia and bipolar disorder examined whether cortical thickness associated MMN, exploratory purposes.Electroencephalograms were recorded 38 schizophrenia, 37 disorder, 32 healthy controls (HCs) performing passive auditory oddball paradigm. All participants underwent T1 structural magnetic resonance...

Structural covariance is described as coordinated variation in brain morphological features, such cortical thickness and volume, among structures functionally or anatomically interconnected to one another. networks, based on graph theory, have been studied mental disorders. This analysis can help understanding the mechanisms of schizophrenia bipolar disorder. We investigated thickness-based individualized structural networks patients with T1-weighted magnetic resonance images were obtained...

Pathologies of schizophrenia and bipolar disorder have been poorly understood. Brain network analysis could help understand brain mechanisms disorder. This study investigates the source-level cortical networks using resting-state electroencephalography (EEG) in patients with disorder.Resting-state EEG was measured 38 schizophrenia, 34 type I, 30 healthy controls. Graph theory based weighted functional were evaluated: strength, clustering coefficient (CC), path length (PL), efficiency six...

Abstract The aim of the study was to explore association between functional outcomes and mismatch negativity (MMN) activity in participants with mood disorders. were 27 subjects major depressive disorder (MDD), 29 bipolar (BD), 33 healthy controls who performed a passive auditory oddball paradigm while electroencephalography (EEG) recorded. Peak amplitudes source MMN compared across groups. Mood anxiety symptoms evaluated. levels lowest BD group, followed by MDD control had significantly...

Natural images containing affective scenes are used extensively to investigate the neural mechanisms of visual emotion processing. Functional fMRI studies have shown that these activate a large-scale distributed brain network encompasses areas in visual, temporal, and frontal cortices. The underlying spatial temporal dynamics, however, remain be better characterized. We recorded simultaneous EEG-fMRI data while participants passively viewed from International Affective Picture System (IAPS)....

Individuals who experience childhood trauma are vulnerable to various psychological and behavioral problems throughout their lifetime. This study aimed investigate whether individuals with show altered frontal lobe activity during response inhibition tasks.

Childhood trauma is known to be related with emotional problems, quantitative electroencephalography (EEG) indices, and heart rate variability (HRV) indices in adulthood, whereas directions among these factors have not been reported yet. This study aimed evaluate pathway models young healthy adults: 1) one physiological first problems later adulthood as results of childhood trauma, 2) later. A total 103 non-clinical volunteers were included. Self-reported psychological scales including the...

The aim of this study is to examine social functioning in patients with schizophrenia and bipolar disorder explore the psychological neurophysiological predictors functioning.Twenty-seven thirty disorder, as well twenty-five healthy controls, completed measures (questionnaire functioning), neurocognition (Verbal fluency, Korean-Auditory Verbal Learning Test), cognition (basic empathy scale Social Attribution Task-Multiple Choice), childhood trauma questionnaire (CTQ). For measurements,...

Mismatch negativity (MMN) is known to be associated with neuro-cognition and functional outcomes. Remission recovery rates are related the of patients schizophrenia. The present study explored relationship MMN remission in schizophrenia.Forty schizophrenia were recruited divided into two groups, or without remission, according Schizophrenia Working Group criteria (RSWGcr). Symptom severity (Positive Negative Syndrome Scale, PANSS), cognitive function, outcome, evaluated. A regression...

Studies comparing bipolar disorder (BD) and major depressive (MDD) are scarce, the neuropathology of these disorders is poorly understood. This study investigated source-level cortical functional networks using resting-state electroencephalography (EEG) in patients with BD MDD. EEG was recorded 35 BD, 39 MDD, 42 healthy controls (HCs). Graph theory-based weighted were assessed via strength, clustering coefficient (CC), path length (PL) six frequency bands. At global level, MDD showed higher...

Electroencephalography (EEG) is a supplementary diagnostic tool in psychiatry but lacks practical usage. EEG has demonstrated inconsistent ability because major depressive disorder (MDD) heterogeneous psychiatric with complex pathologies. In clinical psychiatry, it essential to detect these complexities using multiple paradigms. Though the application of machine learning signals increased, an improvement its classification performance still required clinically. We tested paradigms drug-naïve...

Abstract Background Patients with post-traumatic stress disorder (PTSD) show a different stress-related cognitive style compared healthy controls (HC). The FK506 binding protein 5 gene ( FKBP5 ), one of the PTSD known risk factors, is involved in response through hypothalamic-pituitary-adrenal axis and brain volumetric alterations. present study aimed to uncover neural correlates styles analysis regional volumes genotype patients HC. Methods In this study, 51 94 HC were assessed for styles,...

Background: Psychiatric diagnosis is formulated by symptomatic classification; disease-specific neurophysiological phenotyping could help with its fundamental treatment. Here, we investigated brain in patients schizophrenia (SZ) and major depressive disorder (MDD) using electroencephalography (EEG) conducted machine-learning-based classification of the two diseases EEG components. Materials Methods: We enrolled healthy controls (HCs) (n = 30) SZ 34) MDD 33). An auditory P300 (AP300) task was...

Loudness dependence of auditory evoked potentials (LDAEP) has been proposed as a biological marker central serotonergic activity related to suicides. This study's objective was analyze the difference in LDAEP between depressed patients with suicide attempts (SA) and suicidal ideation (SI). It included 130 participants (45 SA, 49 SI, 36 healthy controls) aged > 18 years who exhibited during electroencephalography. Psychological characteristics event-related three groups were compared. There...