Background Research investigating the association between varicose veins (VV) and heart failure has been limited. Here, we examine this within a nationwide longitudinal cohort, hypothesizing an increased risk of associated with presence VV. Methods Our study included 390,436 participants based on health screening results conducted from 2005 to 2010 in South Korean cohort database. Presence VV was defined as having at least two claims International Classification Diseases, Tenth Revision...

Several risk factors for osteoporotic fractures have been identified but reports of the association lipid parameters with occurrence limited. We aimed to examine whether serum total cholesterol (TC) variability is associated fractures. The study included 3,00,326 subjects who had undergone three or more health examinations between 2003 and 2008. primary endpoint was incidence fractures, including vertebral, hip, distal radius, humerus TC evaluated based on following parameters: coefficient...

Rechargeable seawater batteries (SWBs) use Na + ions dissolved in water (seawater or salt-water) as the cathode material. They are attracting attention for marine applications such light buoys, drones, auxiliary power sailing boats and so on. So far, SWB design has been developed from coin-type to prismatic-shape cell research purposes investigate components electrochemical behaviors. However, commercial applications, that generally require >12 V >15 W, development of an module is...

Gamma-glutamyl transferase (GGT) is related to inflammation, osteoporosis, and vascular diseases. Recently, changes in metabolic parameters have been proposed as osteoporosis biomarkers. We aimed assess longitudinally the association of GGT variability with osteoporotic fractures.From National Health Insurance Service-Health Screening Cohort database, participants who underwent three or more health examinations between 2003 2008 were included (n = 1,072,432). Variability indexes follows: (1)...

Abstract Backgrounds Although the short‐term efficacy of bilateral subthalamic deep brain stimulation (DBS) has been reported in a limited number Parkinson's disease (PD) patients with SNCA mutations, there are no data for long‐term outcome. Methods This multicenter retrospective study investigated previously PD implanted DBS. We compared demographic and clinical at baseline last follow‐up. Clinical motor nonmotor symptoms fluctuation were collected up to 10 years from DBS surgery. Results...

Abstract We explored the associations of actigraphy-derived rest-activity patterns and circadian phase parameters with clinical symptoms level 1 polysomnography (PSG) results in patients chronic insomnia to evaluate implications for PSG interpretation. Seventy-five participants underwent actigraphy assessments PSG. Exploratory correlation analyses between derived from actigraphy, PSG, were performed. First, classified into two groups based on pattern variables; group differences investigated...

Purpose: To compare the characteristics of obstructive sleep apnea (OSA) between patients with epilepsy and without to investigate CPAP (Continuous Positive Airway Pressure) effect on seizures. Methods: Medical polysomnography (PSG) data from 235 adult OSA (OE; 183 males; mean age, 49.8 years) 268 age- sex-matched (OSE; 216 51.3 years), obtained March 2014 May 2020 housed in a database university-affiliated hospital, were retrospectively reviewed. All subjects completed surveys addressing...

Objectives: Galaxy Watch 3 (GW3) is a commercially available smartwatch equipped with sleep-tracking function capable of collecting longitudinal sleep data in real-world environment. We aimed to investigate the validity GW3 for estimating stages compared reference from polysomnography (PSG).Methods: Thirty-two healthy adults (mean age 37.8, male 87.5%) were recruited wear concurrently in-laboratory overnight PSG recording. Sleep parameters, including total time (TST) and duration each stage...

Systemic capillary leak syndrome (SCLS) is a rare and potentially life-threatening disorder characterized by reversible plasma extravasation vascular collapse. This study aimed to investigate the association between different types of COVID-19 vaccine SCLS in real-world setting. We used individual case safety reports after vaccination from WHO pharmacovigilance database, VigiBase. A disproportionality analysis ChAdOx1 nCoV-19 mRNA-based vaccines was performed. The information component (IC)...

: Abnormal epileptic discharges in the brain can affect central regions that regulate autonomic activity and produce cardiac symptoms, either at onset or during propagation of a seizure. These alterations are related to cardiorespiratory disturbances, such as sudden unexpected death epilepsy. This study aims investigate differences function between patients with temporal lobe epilepsy (TLE) frontal (FLE) using ultra-short-term heart rate variability (HRV) analysis around seizures.

We aimed to investigate relationships between sleep disturbances and phenoconversion neurodegenerative diseases in patients with REM behavior disorder (RBD).Using a comprehensive database university-affiliated hospital December 2014 March 2021, we reviewed the data of 226 RBD (182 idiopathic (iRBD) 44 symptomatic (sRBD) disease).Among (male, 61.5%), mean age at onset disease duration were 59.4 ± 10.5 5.9 5.6 years, respectively. Further, 111 (49.1%) had periodic limb movements during (PLMS,...

High glucose levels can change podocyte gene expression and subsequently induce damage through altered metabolism. l-Carnitine is known to play a beneficial role in diabetes; however, there are no studies on the effects of l-carnitine alteration under high conditions. This study investigated whether attenuate diabetic injury prevention loss slit diaphragm proteins. The treatment group showed increased uptakes compared control group, suggesting that utilization podocytes was by l-carnitine....

Wrist-based respiratory rate (RR) measurement during sleep faces accuracy limitations. This study aimed to assess the of RR estimation function based on severity obstructive apnea (OSA) using Samsung Galaxy Watch (GW) series. These watches are equipped with accelerometers and photoplethysmography sensors for estimation. A total 195 participants visiting our clinic underwent overnight polysomnography while wearing GW, estimated by GW was compared reference obtained from nasal thermocouple....

Background andObjective: In the present study, a detailed investigation of substructural volume change in hippocampus (HC) and amygdala (AMG) was performed association with clinical features patients mesial temporal lobe epilepsy hippocampal sclerosis (TLE-HS) determined. Methods: The study included 22 left-sided TLE-HS (LTLE-HS) 26 right-sided (RTLE-HS). addition, 28 healthy controls underwent high-resolution T2-weighted image (T2WI) T1-weighted (T1WI) MRI scanning. Subfield analysis HC AMG...

This study aims to compare directed transfer function (DTF), which is an effective connectivity analysis, derived from scalp EEGs between responder and nonresponder groups implanted with vagus-nerve stimulation (VNS). Twelve patients drug-resistant epilepsy (six responders six nonresponders) ten controls were recruited. A good response VNS was defined as a reduction of ≥50% in seizure frequency compared the presurgical baseline. DTF calculated five bands (delta, theta, alpha, beta,...

Objectives: Sleep issues are more prevalent in healthcare workers compared to other industries. This study investigated sleep-wake pattern, sleep quality, and daytime status hospital using a Galaxy Watch3 (GW3), wrist-worn device that uses an accelerometer heart rate sensor distinguish wakefulness.Methods: Multiple parameters including total time (TST) were obtained GW3. The Epworth sleepiness scale (ESS), insomnia severity index (ISI), Pittsburgh quality (PSQI), bedtime procrastination...

Motor impersistence, an inability to sustain a certain position or movement, is motor-intentional disorder, caused more often by right than left hemisphere lesions. Since the dominant for mediating motor persistence, callosal lesions that disconnect from may induce impersistence of upper and lower limbs. After undiagnosed infarction, 65-year-old right-handed man suddenly developed transient loss volitional movement his leg. Five days after onset, he was admitted our hospital with signs...

Abstract Introduction This study examines the difference in sleep hygiene status according to age and sex relationship between insomnia non-clinical Korean population using Sleep Hygiene Practice Scale (SHPS-K), validated through this study. Methods We recruited adults (Aged 18-65) without a history of neurologic, psychiatric, or medical disorders diagnosed disorders. An online survey was done SHPS-K, Pittsburgh Quality Index (PSQI-K), Insomnia Severity (ISI-K), Epworth Sleepiness (KESS)....

Objectives This study aimed to validate the Korean version of sleep hygiene practice scale (SHPS-K) and determine its effectiveness in screening poor sleepers with insomnia.

Objectives To investigate the etiologies of sleep disorders according to sex. Methods We enrolled 1,270 patients who complained insomnia (n=328) or apnea (n=942) for more than 6 months and classified them into primary (PI, n=120), comorbid obstructive with (COMISA, n=146), (OSA, n=884) groups based on their polysomnography (PSG) findings, demographics, sleep-related symptoms, questionnaire results (Insomnia Severity Index Epworth Sleepiness Scale). Results The highest prevalence females was...