John Thygesen

ORCID: 0000-0003-4686-2573
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About
Contact & Profiles
Research Areas
  • Glaucoma and retinal disorders
  • Retinal Diseases and Treatments
  • Corneal surgery and disorders
  • Ocular Surface and Contact Lens
  • Offshore Engineering and Technologies
  • Neurological Disorders and Treatments
  • Traumatic Ocular and Foreign Body Injuries
  • Retinal Imaging and Analysis
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Retinopathy of Prematurity Studies
  • Intraocular Surgery and Lenses
  • Ophthalmology and Visual Impairment Studies
  • Risk and Safety Analysis
  • Cerebral Venous Sinus Thrombosis
  • Laser Material Processing Techniques
  • Diversity and Career in Medicine
  • Ophthalmology and Eye Disorders
  • Neuroendocrine Tumor Research Advances
  • Ocular Infections and Treatments
  • Tryptophan and brain disorders
  • Neurological Complications and Syndromes
  • Laser Applications in Dentistry and Medicine
  • Oil and Gas Production Techniques
  • Gastric Cancer Management and Outcomes
  • Hormonal Regulation and Hypertension

Rigshospitalet
1951-2024

Copenhagen University Hospital
2005-2024

Indiana University – Purdue University Indianapolis
2019

Glostrup Hospital
2009-2015

University of Copenhagen
1979-2011

Vejle Sygehus
2000

University of Würzburg
1999

Hvidovre Hospital
1982

Carlsberg Laboratory
1951

10.1016/s0161-6420(96)30407-7 article EN Ophthalmology 1996-11-01

To determine the risk of glaucoma after surgery for pediatric cataract and to evaluate factors glaucoma.A population-based cohort all children in Denmark aged 0 17 years during period 1977 2001, who underwent cataract, was established by retrospective chart review. Glaucoma cases were defined as those which (trabeculectomy and/or diode laser transscleral cyclophotocoagulation) performed permanent medical therapy prescribed surgery.Of 946 eyes (595 patients) undergoing surgery, 72 (48 had...

10.1167/iovs.07-1156 article EN Investigative Ophthalmology & Visual Science 2008-04-24

The purpose of the present study was to describe prevalence, incidence and geographic variation glaucoma in Denmark period from 1996 2011. Moreover, aim identify treatment patterns within studied period.All Danish citizens were included throughout period. National Prescription Registry used all claimed prescriptions for medication.A total 116,592 incident patients identified. Average age at onset 66 years (range: 0-105 years), 55% women. prevalence increased 0.79% 1.72% during investigated...

10.1371/journal.pone.0132048 article EN cc-by PLoS ONE 2015-07-16

Objective: The purpose of this study was to estimate costs and quality life (QoL) late-stage glaucoma patients in 4 European countries.Methods: Retrospective review medical charts with POAG who were followed a low-vision or vision rehabilitation center one countries for at least 1 year used determine patient characteristics, health status, care resource use. Visual impairment measured by best-corrected visual acuity (Snellen score). Patients also interviewed over the telephone order assess...

10.1185/03007990802111068 article EN Current Medical Research and Opinion 2008-05-09

Abstract Background Diminutive colorectal polyps resected during colonoscopy are sometimes histologically interpreted as normal tissue. The aim of this observational study was to explore whether errors in specimen handling or processing account part for ≤ 3 mm size being tissue by pathology when they were considered high confidence adenomas an experienced endoscopist at colonoscopy. Methods One photographed 900 consecutive lesions that and endoscopically be conventional adenomas. photographs...

10.1055/a-0831-2348 article EN Endoscopy 2019-02-05

ABSTRACT. Purpose: To investigate and compare the short term effects of topical latanoprost timolol on tear fluid ocular surface condition in patients with bilateral primary open angle glaucoma or hypertension. Methods: Thirty‐seven were included this randomized, double‐masked, parallel group study. Patients received either 0.005% (n=18) 0.5% ( n =19) instilled once daily morning for a treatment period 27 days. Routine ophthalmic examinations, including intraocular pressure measurement, as...

10.1034/j.1600-0420.2000.078001037.x article EN Acta Ophthalmologica Scandinavica 2000-02-01

We have developed through a consensus process 24 clinical recommendations for the comprehensive management of ocular surface inflammation in glaucoma patients, including diagnostic criteria, prevention measures, and treatment strategies according to disease severity. To obtain expert on diagnosis, prevention, (OSI) patients with glaucoma. An international steering committee and/or (OSD) experts wider faculty members from Educational Club Ocular Surface Glaucoma (ECOS-G) collaborated develop...

10.1097/ijg.0000000000002465 article EN Journal of Glaucoma 2024-07-17

Corneal astigmatism after cataract surgery by way of corneal incision (C, n = 62) and corneo‐scleral (CS, 61) was followed for six months. incisions were closed continuous nylon 10–0 (7–25 loops, median 14). Corneo‐scleral sutured with single knots (2–10, value 5). Keratometric results in the C CS groups are compared. Concerning degree astigmatism, pre‐operative values 0.5 0.7 D, respectively. After one week they 4.5 3.0 D; two weeks 3.3 four months 2.0 (final status) 1.5 1.7 The differences...

10.1111/j.1755-3768.1979.tb00488.x article EN Acta Ophthalmologica 1979-04-01

Objective: To compare the efficacy and cost implications of use intraocular pressure-lowering prosta­glandin analogues bimatoprost, travoprost, latano­prost as fixed-combination therapies with timolol, a β-adrenergic receptor antagonist.Methods: A decision analytic cost-effectiveness model was constructed. Since no head-to-head studies comparing three treatment options exist, analysis based on an indirect comparison. Hence, data from five randomized, controlled, clinical studies. The were...

10.1185/030079908x280626 article EN Current Medical Research and Opinion 2008-02-29

Efficacy, safety, and cost implications are important considerations when choosing an ophthalmic treatment. Fixed-combination glaucoma medications containing brimonidine 0.2% timolol 0.5%, or dorzolamide 2% were compared with that used as adjunctive therapy to 0.5%.A literature review was conducted determine the outcome parameters of intraocular pressure reduction tolerability after 3 months use dorzolamide, each together a fixed-combination in concomitant therapy. Modelled cost-minimization...

10.1177/112067210801800519 article EN European Journal of Ophthalmology 2008-09-01

A 9-year-old girl with neurofibromatosis type 1 (NF1) (Fig. 1A) and a 1-year history of controlled left unilateral juvenile glaucoma, related to congenital ectropion uveae, presented rapid, unexplained, painless visual loss in the eye. Eight months after onset loss, best corrected acuity was 20/20 right 20/200 relative afferent pupillary defect observed Right eye examination normal. There minimal proptosis mild ptosis. Slit-lamp disclosed uveae 1B) fundoscopy showed glaucomatous cupped optic...

10.1111/j.1755-3768.2008.01431.x article EN Acta Ophthalmologica 2009-02-07

10.3109/00365515109060574 article EN Scandinavian Journal of Clinical and Laboratory Investigation 1951-01-01

Abstract In the clinical management of patients at risk for or diagnosed with primary open-angle glaucoma (POAG), aim medical treatment is to reduce intraocular pressure (IOP) and then maintain it over time a level that preserves both structure function optic nerve. The objective this report was establish consensus on criteria should be used determine characteristics IOP-lowering medication. Discussion held among panel 12 physicians considered experts in develop by them medication chosen...

10.1016/j.curtheres.2007.06.002 article EN publisher-specific-oa Current Therapeutic Research 2007-05-01

A case of bilateral transient ischaemic blindness (amaurosis) due to changes in the retina, optic nerve and chiasma caused by severe cerebral arterial spasms after subarachnoid haemorrhage (SAH) originating from a ruptured saccular aneurysm (from anterior artery) is presented. To our knowledge this pathogenesis for has never been described before.

10.1111/j.1755-3768.1982.tb08388.x article EN Acta Ophthalmologica 1982-04-01

To evaluate the validity and reliability of new Fast Assessment Ocular Surface Trouble (FAST®) questionnaire for identifying glaucoma or ocular hypertension (OHT) patients at risk surface disease (OSD).

10.1177/11206721231222939 article EN European Journal of Ophthalmology 2024-02-22

Purpose Is the new micropenetrating, clear-cornea procedure, intrastromal diathermal keratostomy (IDK), an alternative to intricate “modern trabeculectomy”? Methods Prospective multicenter study. Four surgeons from 4 Danish eye departments attended IDK course and subsequently decided when start their consecutive series. The data were analyzed centrally. Injection of preoperative, subconjunctival doses mitomycin C (MMC) was recommended according risk-of-failure. A total 54 eyes 48 patients...

10.1097/ijg.0b013e31815a3455 article EN Journal of Glaucoma 2008-06-01

Motivated behaviors share the common feature of activating mesolimbic dopamine system. Repeated experience with motivated can cause long-lasting structural changes in nucleus accumbens (NAc). The molecular mechanisms underlying this experience-dependent plasticity NAc have been well described following drugs abuse. In particular, transcription factor Delta FosB (ΔFosB) is a key regulator drug-related neuroplasticity. Fewer studies examined naturally behaviors, but previous research has...

10.1037/bne0000313 article EN Behavioral Neuroscience 2019-03-14

Purpose The purpose of the present study was to describe prevalence, incidence and demographic variation glaucoma patients in Denmark period from 1996 2011. Moreover, aim identify treatment pattern medication within studied period. Methods population comprised all individuals living 1996‐2011. National Prescription Registry used claimed prescriptions for medication. Results A total 116,592 incident were identified. Average age at onset 66 years (range: 0‐105 year), 55% women. over prevalence...

10.1111/j.1755-3768.2015.0529 article EN Acta Ophthalmologica 2015-09-23
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