Lu He

ORCID: 0000-0003-4713-8712
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About
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Research Areas
  • Luminescence Properties of Advanced Materials
  • Liquid Crystal Research Advancements
  • Luminescence and Fluorescent Materials
  • Nanoplatforms for cancer theranostics
  • Advanced biosensing and bioanalysis techniques
  • Flame retardant materials and properties
  • Insect Resistance and Genetics
  • Carbon and Quantum Dots Applications
  • Synthesis and properties of polymers
  • Photochromic and Fluorescence Chemistry
  • CRISPR and Genetic Engineering
  • Colorectal Cancer Surgical Treatments
  • Advanced Materials and Mechanics
  • Colorectal Cancer Screening and Detection
  • Advanced Sensor and Energy Harvesting Materials
  • Photodynamic Therapy Research Studies
  • Synthesis and Properties of Aromatic Compounds
  • Epoxy Resin Curing Processes
  • Gastric Cancer Management and Outcomes
  • Viral Infectious Diseases and Gene Expression in Insects

Central China Normal University
2024

Soochow University
2013-2020

First Affiliated Hospital of Soochow University
2013-2020

Nanjing University
2017

Lanzhou Jiaotong University
2017

Northeastern University
2011

Upconversion nanoparticles (UCNPs) have drawn much attention in cancer imaging and therapy recent years. Herein, we for the first time report use of UCNPs with carefully engineered surface chemistry combined photodynamic (PDT) gene cancer. In our system, positively charged NaGdF4:Yb,Er multilayered polymer coatings are synthesized via a layer by strategy, then loaded simultaneously Chlorin e6 (Ce6), photosensitizing molecule, small interfering RNA (siRNA), which targets Plk1 oncogene. On one...

10.1039/c4nr02495h article EN Nanoscale 2014-06-03

Upconversion nanoparticles (UCNPs) have been widely explored for various bioapplications because of their unique optical properties, easy surface functionalization, and low cytotoxicity. Herein, we synthesize gadolinium (Gd3+)-doped UCNPs, which are modified first with poly(ethylene glycol) (PEG) then two layers poly(ethylenimine) (PEI) via covalent conjugation layer-by-layer assembly, respectively. Compared UCNP-PEG@1×PEI only one layer PEI coating, the final complex, UCNP-PEG@2×PEI,...

10.1021/am403554x article EN ACS Applied Materials & Interfaces 2013-09-27

10.1016/j.colsurfa.2025.136814 article EN Colloids and Surfaces A Physicochemical and Engineering Aspects 2025-04-01

A novel luminescence 'Turn-On' nanoplatform for the sensitive sensing of Ag+ was fabricated based on resonance energy transfer technique between sodium citrate functionalized upconversion nanoparticles (Cit-UCNPs, donor) and graphene quantum dots (GQDs, acceptor). Amino-labeled single-stranded DNA (NH2-ssDNA) containing a number cytosine (C) conjugated surface Cit-UCNPs to capture ions. Due π–π stacking interaction NH2-ssDNA GQDs, can be quenched. However, upon addition Ag+, weakens due...

10.1088/2050-6120/aa6e0d article EN Methods and Applications in Fluorescence 2017-05-05

With the increasing incidence of pest resistance to transgenic crops producing Bacillus thuringiensis (Bt) proteins in field, elucidating molecular basis is important for monitoring, delaying and countering resistance. Previous work revealed that mutation or down-regulated expression cadherin gene (PgCad1) associated with pink bollworm (Pectinophora gossypiella) Cry1Ac, 20 mutant PgCad1 alleles (r1-r20) were characterized. Here, we tested hypothesis ABC transporter PgABCC2 a functional...

10.1002/ps.8036 article EN Pest Management Science 2024-02-21

Data regarding computed tomography colonography, standard optical colonoscopy, and enhanced colonoscopy/histopathology at 1-year after surgery 6-month intervals for the next 2 years of 345 patients who faced curative colorectal cancer were included in this analysis. Computed colonography colonoscopy both detected 298 polyps as suspicious. With reference to colonoscopy/histopathology, sensitivities detection any 0.952 0.906, while, accuracies 0.783 0.641, respectively. may be a sensitive...

10.1080/07357907.2020.1771724 article EN Cancer Investigation 2020-05-19
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