A5054522661- Veterinary Equine Medical Research
- Animal health and immunology
- Renal function and acid-base balance
- Venous Thromboembolism Diagnosis and Management
- Streptococcal Infections and Treatments
- Veterinary medicine and infectious diseases
- Diphtheria, Corynebacterium, and Tetanus
- Muscle metabolism and nutrition
- Respiratory Support and Mechanisms
- Cardiovascular Conditions and Treatments
- Thermodynamic properties of mixtures
- Sepsis Diagnosis and Treatment
- Intestinal and Peritoneal Adhesions
- Blood groups and transfusion
- Reproductive Physiology in Livestock
- Animal Nutrition and Physiology
- Neuroscience of respiration and sleep
- Neonatal Respiratory Health Research
- Lipid metabolism and disorders
- Amoebic Infections and Treatments
- Ocular Infections and Treatments
- Bacterial Infections and Vaccines
- Plant Toxicity and Pharmacological Properties
- Diagnosis and Treatment of Venous Diseases
- Muscle Physiology and Disorders
Fundació Clínic per a la Recerca Biomèdica
2018-2025
Universitat Autònoma de Barcelona
2015-2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2010-2011
University of Caldas
2010
Hospital Clínic de Barcelona
2010
Increased synovial fibrinolytic activity (detected by increases in D-Dimer concentrations) has been observed different joint diseases humans and adult horses, presumably order to minimize fibrin deposition within the thus avoid its detrimental effects.To investigate pathway activation sepsis foals measuring concentrations.Eighteen septic with joints, 9 without systemically healthy joint, 3 controls are included.Prospective observational clinical study of admitted for arthritis. Synovial...
Equine herpesvirus myeloencephalopathy (EHM) is a persistent threat to horses, with unclear risk factors and disease severity. To evaluate factors, effective reproduction rate (Rt), long-term athletic outcomes of an EHM outbreak. Retrospective study the 2021 outbreak in Valencia, Spain, examining associations between (sex, age, breed, country origin, vaccination status) case fatality rate, development, odds returning competition using ratios [95% CI] Rt via Robert Kochs Institute method....
Septicemia in human neonates frequently is complicated by activation of the coagulation system, disseminated intravascular (DIC) and multiple organ failure syndrome, which may contribute to high mortality. In adult horses with DIC, lung has been most affected fibrin deposits. addition, vivo studies suggest that hemostatic mechanisms be immature foals < 1-day old.Newborn severe septicemia have deposits their tissues independently age, these are associated failure.Thirty-two septic 4 nonseptic...
Septicemia is associated with a systemic inflammatory response, hemostatic activation, and disseminated intravascular coagulopathy (DIC).Increased plasma d-dimer concentration occurs in septic neonates can reliably detect sepsis or DIC, predict death ill neonatal foals.40 septic, 41 nonseptic hospitalized foals, 22 healthy neonates.Prospective observational clinical study. Blood samples were collected on admission, at 24-48 hours after the time of discharge euthanasia. Plasma concentration,...
Background: Plasma d ‐dimer concentration is a useful marker to assess systemic coagulation and fibrinolytic activities in humans, dogs, horses. Peritoneal activity increases horses with colic, especially endotoxin the peritoneal fluid. Hypothesis/Objectives: can be used severe gastrointestinal (GI) disorders altered Animals: Two hundred twenty‐one colic 15 control Methods: Prospective observational clinical study. Blood fluid were collected on admission. Horses grouped according diagnosis,...
Acid-base disturbances are traditionally assessed using the Henderson-Hasselbach equation. The simplified strong ion approach describes more accurately complex acid-base and electrolyte abnormalities present in endurance horses.To describe electrolytes changes fit horses competing a FEI*** 120 km race to compare traditional vs. approaches.Thirty were initially enrolled study. Venous blood samples obtained before (n = 25), at second 29; 65.4 km) third vet-gates 23, 97.4 upon completion 17)....
Background: Coagulopathies detected in horses with gastrointestinal problems seem to be associated poor outcome. Plasma D-Dimer concentration is a sensitive test for assessing coagulopathies. Hypothesis: tested on admission related diagnosis and outcome colic. Animals: Four hundred ninety three referred evaluation of abdominal pain. Methods: Prospective observational clinical study. Horses were grouped according (medical surgical intestinal obstructions, ischemic disorders without resection,...
To assess the effect of enteral fluid therapy (EFT) in horses with colic, 78 adult colon impactions and 30 left dorsal displacements received an isotonic electrolyte solution via a nasogastric tube at rate 8 to 10 l every two hours until resolution clinical signs. Clinical progression was monitored closely, plasma biochemistry evaluated before, during after treatment. Volume fluids, time resolution, outcome were also recorded. EFT well tolerated by 102 108 effective method resolve 99 per...
Bacterial meningoencephalitis is a severe complication in septic foals and there scarce often unclear information the equine literature.To report most frequent clinical signs, clinicopathological findings, causative agents, treatments given outcome of group with confirmed bacterial meningoencephalitis.Foals aged < 6 months age admitted to Universitat Autonoma de Barcelona (2004-2009) were retrospectively included study Diagnosis was made by cerebrospinal fluid (CSF) culture, CSF analysis...
Background Sick neonatal foals suffer from a variety of endocrine and metabolic derangements that may be related to outcome. There are several hepatic lipid metabolism blood markers have never been assessed in foals. Objectives Assess panel variables group sick healthy order describe their relationship with diagnosis survival. Animals All referred Unitat Equina‐Fundació Hospital Clínic Veterinari during 3 consecutive foaling seasons Methods Observational prospective study. Blood samples were...
Recent advances have significantly enhanced the use of smartphone devices for medical diagnostics. This study uses high-resolution cameras in mobile to capture and process bioassay images, enabling quantification diverse biomarkers across a range diagnostic tests conducted on 96-well microplates. The evaluates effectiveness this technology through protein techniques immunoassays that generate colorimetric responses at specific wavelengths. It includes assessment bicinchoninic acid Bradford...
The purposae of this study was to compare traditional and quantitative approaches in analysis the acid-base electrolyte imbalances horses with acute gastrointestinal disorders. Venous blood samples were collected from 115 colic horses, 45 control animals. Horses grouped according clinical diagnosis into 4 categories: obstructive, ischemic, inflammatory, diarrheic problems. Plasma electrolytes, total protein, albumin, pH, pCO2, tCO2, HCO3-, base excess, anion gap, measured strong ion...
The purposae of this study was to compare traditional and quantitative approaches in analysis the acid-base electrolyte imbalances horses with acute gastrointestinal disorders. Venous blood samples were collected from 115 colic horses, 45 control animals. Horses grouped according clinical diagnosis into 4 categories: obstructive, ischemic, inflammatory, diarrheic problems. Plasma electrolytes, total protein, albumin, pH, pCO2, tCO2, HCO3-, base excess, anion gap, measured strong ion...
Mean platelet component (MPC) is a new variable, measured by modern commercial complete blood count analyzers, that reduced during activation in humans and small animals.MPC decreases horses with clinical conditions cause disseminated intravascular coagulation (DIC).We obtained 418 CBCs from 100 sick 20 healthy neonates 178 45 sound adult horses. Sick were classified into septic nonseptic, DIC non-DIC groups. Adults grouped diagnoses (systemic inflammatory disorders, gastrointestinal...
Septicemia in humans is described as a leading cause of uveitis, which eventually can induce blindness.Uveal inflammatory findings could be related to sepsis severity newborn foals and might used an indirect indicator for survival.Seventy-four septic foals, 54 nonseptic 42 healthy foals.Prospective observational clinical study. A detailed blinded, ophthalmic examination was performed by boarded ophthalmologists on all admitted foals. Foals were grouped (when blood culture resulted positive...
Nutritional support in critically ill neonatal foals is of great importance given their high metabolic rate and minimal stores energy protein. Nutrient requirements healthy growing have been estimated based on daily milk intake; however, little known about the resting expenditure (REE) sick foals.To determine REE (sepsis and/or hypoxic-ischaemic encephalopathy [HIE] compare this with control foals.Critically newborn admitted to Fundació Hospital Clinic Veterinari, Universitat Autònoma de...
Abstract Objective To assess the progression of plasma D‐dimer concentrations and coagulation status in horses with different types colic. Design Prospective clinical observational study performed between March 2004 September 2008. Setting Veterinary university teaching hospital. Animals Horses admitted treated for colic hospitalized >48 hours were considered. classified by diagnosis into medical obstructive conditions (MO), surgical (SO), inflammatory conditions, ischemic lesions (IS)....
Abstract Objective To describe clinical data of hospitalized adult equids and foals with tetanus. Design Multicenter retrospective study (2000–2014). Setting Twenty Western, Northern, Central European university teaching hospitals private referral centers. Animals One hundred fifty‐five (>6 months) 21 (<6 Interventions None. Measurements Main Results Information on geographic, annual seasonal data, demographic‐ management‐related history, examination blood analysis admission,...
Athletic taping is used frequently by human athletes to stabilise, maintain or strengthen soft tissue structures, but empirical evidence supporting any changes in equine kinematics lacking.To assess the effects of athletic fetlock applied an experienced trainer on forelimb mechanics healthy horses.That distal reduces 1) hyperextension joint during stance, 2) flexion swing and 3) ground reaction forces stance.Ground force kinematic data were obtained for 6 horses trotting at 3 m/sec 4...
Heparin is used in humans as prophylaxis of hypercoagulable states and disseminated intravascular coagulation (DIC). However, babies need a higher heparin dose than do adults. Septic neonate foals are at high risk state DIC, there limited objective information about for equine neonates.To assess whether require dosages low-molecular-weight (LMWH) adults.Eighteen healthy 11 septic foals.Experimental clinical studies. Firstly, were randomly distributed 2 groups, 1 receiving 50 IU/kg SC...
A 16-year-old Westfalian gelding was presented to the Equine Teaching Hospital of Barcelona for a 6-week history sudden, progressive bilateral abnormal gait in pelvic limbs. Previous treatment with phenylbutazone and paralumbar corticosteroid (triamcinolone) infiltration had not resulted improvement. The horse lived 2 years same pasture other unaffected horses. None horses developed clinical signs consistent stringhalt. No recent trauma reported. did have any previous medical problems, apart...
Acid-base imbalances observed in human paediatric patients are associated with outcome. Likewise, neonatal foals may have different acid-base diagnosis or prognosis.To determine by the quantitative method ill and assess their association prognosis.Observational prospective clinical study.This study included 65 (32 septic, 33 nonseptic) admitted to an equine referral hospital from 2005 2011with parameters determined on admission a control group of healthy foals. Blood pH, pCO2 , sodium,...
To assess the prevalence of exercise-induced pulmonary hemorrhage (EIPH) among elite endurance horses after competition in a long-distance race.20 and 12 nonexercised or minimally exercised age-, breed-, trainer-matched from same environment (control horses).Bronchoalveolar lavage fluid samples collected at 3 to 8 days (sample A) 36 38 B) race (100 km 1 day [n = 3], 70 km/d for 2 [12], 100 [5]) were cytologically examined presence hemosiderophages. Samples control time as sample B was...
Disseminated intravascular coagulation (DIC) is frequent in horses with severe gastrointestinal disorders. Postmortem studies have found fibrin microthrombi tissues of these horses, but relating histopathological findings antemortem hemostatic data are lacking.Antemortem classification coagulopathy related to the presence and severity deposits observed postmortem disorders.Antemortem profile tissue samples (kidney, lung, liver) from 48 colic.Tissue were stained phosphotungstic acid...
To determine if plasma iron concentration is different between horses with and without systemic inflammation (SI) to assess the accuracy for detection of SI by assaying fibrinogen concentrations, individually or combined. prognostic value describe progression concentrations during hospital follow-up, its relation survival.Prospective observational study evaluating fibrinogen.University veterinary teaching hospital.Equine patients greater than 30 days age.None.Plasma was prospectively...