A5042499747- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Vestibular and auditory disorders
- Neuroscience and Neuropharmacology Research
- Migraine and Headache Studies
- Alzheimer's disease research and treatments
- Hearing, Cochlea, Tinnitus, Genetics
- Multiple Sclerosis Research Studies
- Pregnancy and Medication Impact
- Hemoglobinopathies and Related Disorders
- Neurological disorders and treatments
- Diet and metabolism studies
- Fetal and Pediatric Neurological Disorders
- Glycogen Storage Diseases and Myoclonus
- Cerebral Venous Sinus Thrombosis
- Vitamin K Research Studies
- Drug Transport and Resistance Mechanisms
- Leprosy Research and Treatment
- Systemic Sclerosis and Related Diseases
- Biomarkers in Disease Mechanisms
- Peripheral Neuropathies and Disorders
- Hereditary Neurological Disorders
- Myofascial pain diagnosis and treatment
- Heat shock proteins research
- Peripheral Nerve Disorders
Ümraniye Eğitim ve Araştırma Hastanesi
2013-2024
Sağlık Bilimleri Üniversitesi
2018-2023
Turkish Society of Hematology
2019
University of Health Sciences
2019
Şişli Etfal Eğitim ve Araştırma Hastanesi
2010
Memorial Sisli Hospital
1998-2006
The link between headache and epilepsy is more prominent in patients with idiopathic/genetic (I/GE). We aimed to investigate the prevalence of cluster regard their features.Patients aged 6-40 years, a definite diagnosis I/GE, were consecutively enrolled. interviewed using standardized questionnaires, characteristics investigated by experts headache. Demographic clinical variables analyzed, clustered according an unsupervised K-means algorithm.Among 809 patients, 508 (62.8%) reported having...
Diabetic polyneuropathy is the most common neurologic complication of diabetes mellitus. Underlying mechanisms diabetic are related to various metabolic and inflammatory pathways. Pentraxin 3 (PTX3) an acute phase protein that produced locally at sites by several cell types. Thioredoxin binding 2 (TBP2) a thioredoxin regulator involved in intracellular energy pathways growth. We measured plasma levels PTX3 TBP2 type patients (n = 27) with pain complaints compared their those healthy age-...
Vestibular migraine (VM) is a clinical condition characterized by temporal overlap between vestibular symptoms and migraine. In this study, we aimed to determine the changes in myogenic potential (cVEMP) auditory brainstem response (ABR) patients with VM migraine.A total of 86 participants no hearing loss or additional disease ages 18 45 were enrolled three different groups: group 1, VM; 2, without aura; 3, healthy controls. cVEMP ABR performed for all during attacks attack-free periods. The...
ABSTRACT Purpose To describe the clinical and electroencephalographic features of three patients diagnosed with Panayiotopoulos syndrome different lesions identified by cranial MRI investigation. Methods Our study was based on from Epilepsy Outpatient Clinic Şişli Etfal Education Hospital in Istanbul, where a prospective initiated 1995. Records our revealed 53 syndrome. Among them were MRI. Results The onset seizures ranged between five eight years. included mainly autonomic symptoms such as...
The present study was aimed at investigating the effects of anti-seizure medications (ASMs), patient demographic characteristics, and seizure type frequency on development congenital malformations (CMs) in infants pregnant women with epilepsy (PWWE).PWWE followed up neurology outpatient clinic 21 centers between 2014 2019 were included this prospective study. follow-up PWWE conducted using structured, general forms prepared by Pregnancy Epilepsy Study Committee. newborns examined a...
Crohn's Disease (CD) is a chronic systemic inflammatory disease associated with various extraintestinal manifestations, including seizure as neurological finding. In this study, the prevalence of and electroencephalographic abnormalities in patients CD was investigated.This study involved 41 (female/male: 25/16) 39 subjects control group 25/14). Patients were diagnosed monitored according to European Colitis Organization diagnostic criteria. The composed healthy similar age sex group....
Abstract Aims . Epileptic vertigo is often a diagnostic problem. We aimed to present the clinical and electrophysiological features of patients with epileptic view addressing pathophysiology this rare aura symptom. Methods Nine were included in study. All subjected neuro‐otologic examination, interictal electroencephalogram (EEG), audiogram, cervical vestibular evoked myogenic potential testing (cVEMP), video head impulse (vHIT) brain magnetic resonance imaging (MRI). Results Eight described...
Cerebral hemiatrophy (or Dyke-Davidoff-Masson Syndrome) is a neurodevelopmental disorder characterized by atrophy or hypoplasia of one cerebral hemisphere accompanied ipsilateral calvarial changes. Clinically, the condition presents with contralateral motor dysfunction, facial asymmetry, epilepsy and intellectual impairment. Psychiatric manifestations are uncommon neuropsychiatric aspect disease not well described. Here, we report 26-year-old female who presented left schizoaffective...
Abstract Objective Homocysteine is a sulfur containing amino acid that formed during methionine metabolism. Patients under long-term antiepileptic drug treatment often have hyperhomocysteinemia. These patients low levels of serum folate, vitamin B12 and B6, all which are associated with homocysteine We investigated the effects valproic new generation drugs (lamotrigine levetiracetam) on plasma aminothiols as well folic acid. Materials methods Forty-seven idiopathic epileptic were compared 38...
Dissection is defined as the leakage of blood from an intravascular compartment into vessel wall.Craniocervical dissections are a major cause stroke, particularly among young adults.Mortality and morbidity rates vary based on dissected dissection location.Although mortality for extracranial carotid vertebral artery reported to be between 5% 10%, increase above 70% intracranial basilar (1).Sildenafil has been commonly used treating erectile dysfunction since 1998.This study presents case in...
Background & Objective: Peripheral neuropathy is the most frequent neurologic complication of inflammatory bowel disease (IBD). We aimed to evaluate clinical utility medial plantar nerve conduction study (NCS) in detection distal sensory polyneuropathy IBD patients. Methods: The was performed with 21 Crohn’s (Group 1) patients, 24 Ulcerative Colitis 2) patients without peripheral and 28 healthy participants 3). Each patient group underwent electrophysiological studies. findings were...
Alzheimer's disease (AD), which is a neurodegenerative disease, cannot be noticed until severe symptoms are observed. This poses global challenge as the average human lifespan increases, making it concern for entire world population. Early diagnosis can play crucial role in slowing progression of thereby enhancing quality life both patient and their relatives. AD has been linked to alterations mRNA expressions. The objective presented study was determine whether there were significant...
Pseudo-vestibular neuritis is a clinical diagnosis for patients presenting with acute vestibular syndrome due to central pathology.We reported case of multiple sclerosis characterized by pseudo-vestibular neuritis. Our was 32-year-old male patient. The patient, who diagnosed in September 2019, came the emergency clinic January 2020 complaint severe vertigo, vomiting-nausea. A newly developed demyelinating plaque detected left nucleus cranial MRI. patient had no hearing loss. On examination...
Objective: The aim is to evaluate the vestibular system using video head impulse test (vHIT) and evoked myogenic potentials (VEMP) in patients with multiple sclerosis (MS) without central involvement magnetic resonance imaging (MRI), determine whether there was subclinical impairment. Materials Methods: study comprised 27 MS 26 healthy participants. participants had no lesions an MRI taken past 3 months. Detailed neuro-otologic neuro-ophthalmologic examinations were performed on all Then,...