A5091639966- Periodontal Regeneration and Treatments
- Dental Implant Techniques and Outcomes
- Oral and gingival health research
- Oral microbiology and periodontitis research
- dental development and anomalies
- Oral and Maxillofacial Pathology
- Bone Tissue Engineering Materials
- Cleft Lip and Palate Research
- Dental Radiography and Imaging
- Dental materials and restorations
- Laser Applications in Dentistry and Medicine
- Reconstructive Surgery and Microvascular Techniques
- Orthodontics and Dentofacial Orthopedics
- Electrospun Nanofibers in Biomedical Applications
- Photoacoustic and Ultrasonic Imaging
- Optical Imaging and Spectroscopy Techniques
- Oral Health Pathology and Treatment
- Tracheal and airway disorders
- Endodontics and Root Canal Treatments
- Infrared Thermography in Medicine
- Geomagnetism and Paleomagnetism Studies
- Solar and Space Plasma Dynamics
- Dental Trauma and Treatments
- Advanced biosensing and bioanalysis techniques
- Non-Invasive Vital Sign Monitoring
Harvard University
2016-2025
Carilion Clinic
2018
Washington University in St. Louis
2014-2017
British Society of Periodontology
2015
Institute of Infection and Immunity
2005-2015
Harvard University Press
2013
Scripps Research Institute
2007
Stanford University
2007
Howard Hughes Medical Institute
2007
Measurement of photon penetration in biological tissues is a central theme optical imaging. A great number endogenous tissue factors such as absorption, scattering, and anisotropy affect the path photons tissue, making it difficult to predict depth at different wavelengths. Traditional studies evaluating wavelengths are focused on spectroscopy that does not take into account heterogeneity within sample. This especially critical shortwave infrared where individual vibration-based absorption...
The optical signature of leaves is an important monitoring and predictive parameter for a variety biotic abiotic stresses, including drought. Such signatures derived from spectroscopic measurements provide vegetation indices - quantitative method assessing plant health. However, the commonly used metrics suffer low sensitivity. Relatively small changes in water content moderately stressed plants demand high-contrast imaging to distinguish affected plants. We present new approach deriving...
In 2016, the American Academy of Periodontology (AAP) embarked on a best evidence consensus (BEC) model scientific inquiry to address questions clinical importance in treatment periodontal and peri-implant diseases conditions. For each focused question addressed below, there is critical mass evidence. However, by itself, that is, judgment an expert panel convened AAP, insufficient support broad conclusions and/or practice guidelines. Members assembled for this BEC have extensive knowledge...
The exchange of mobile genetic elements (MGEs) facilitates the spread functional traits including antimicrobial resistance within bacterial communities. Tools to spatially map MGEs and identify their hosts in complex microbial communities are currently lacking, limiting our understanding this process. Here we combined single-molecule DNA fluorescence situ hybridization (FISH) with multiplexed ribosomal RNA-FISH enable simultaneous visualization both taxa. We mapped bacteriophage (AMR)...
ABSTRACT Aim This study aimed to evaluate and compare the results of combination therapy involving bone grafting two different resorbable collagen membranes in 1‐, 2‐ 3‐wall infrabony defects. Methods A total 174 patients with defects (≥ 7 mm periodontal probing depth) were randomized receive deproteinized bovine mineral (DBBM) either a native porcine non‐crosslinked membrane (N‐CM, control, n = 87) or novel crosslinked (C‐CM, test, 87). Clinical parameters, including depth (PPD), clinical...
Abstract Objective: The purpose of this prospective clinical study was to evaluate peri‐implant soft‐tissue conditions and esthetic fulfillment during a 3‐year follow‐up period following prosthetic rehabilitation. Material methods: As part multi‐center study, 152 ITI dental implants were placed in 80 patients the maxillary anterior region. Fifty‐nine crowns (38.82%) cement retained, while 93 (61.18%) screw retained. At loading 3, 6, 12 36 months post‐loading, modified plaque index (MPI),...
Self‐aggregation of dyes even at low concentrations poses a considerable challenge in preparing sufficiently bright molecular probes for vivo imaging, particularly the conjugation near infrared cyanine to polypeptides with multiple labeling sites. Such self‐aggregation leads significant energy transfer between dyes, resulting severe quenching and brightness targeted probe. To address this problem, we designed novel type dye an asymmetrical distribution charge. Asymmetrical prevents...
Abstract A biologic is a therapeutic agent with biological activity that administered to achieve an enhanced regenerative or reparative effect. The use of biologics has progressively become core component contemporary periodontal practice. However, some questions remain about their safety, indications, and effectiveness in specific clinical scenarios. Given availability for routine the existing amount related evidence, goal this American Academy Periodontology (AAP) best evidence consensus...
Peri-implantitis is a challenging condition to manage and frequently treated using non-surgical debridement. The local delivery of antimicrobial agents has demonstrated benefit in mild moderate cases peri-implantitis. This study compared the safety efficacy chlorhexidine gluconate 2.5 mg chip (CHX chips) as an adjunctive treatment subgingival debridement patients afflicted with peri-implantitis.A multicenter, randomized, single-blind, two-arm, parallel Phase-3 was conducted. implant pocket...
Abstract Background To evaluate the risk indicators associated with midfacial gingival recessions (GR) in natural dentition esthetic regions. Methods Cone‐beam computed tomography (CBCT) results of thirty‐seven subjects presenting 268 eligible teeth were included cross‐sectional study. Clinical measurements presence/absence GR; depth midfacial, mesial, and distal recession; recession type (RT); keratinized tissue width (KT); attached gingiva (AG). Questionnaires utilized to capture...
Recent technological advancements led to the development of various plasma-based technologies for post-packaging modifications. The purpose present preclinical in vivo study was assess safety and efficacy a novel chairside nonthermal gas plasma treatment enhancing osseointegration titanium implants. Six male mixed foxhounds underwent extraction mandibular premolars first molars, sockets healed 42 days. Canine mandibles were randomized receive either plasma-treated (test) or...