Bin Chen

ORCID: 0000-0003-4738-5190
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About
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Research Areas
  • Traditional Chinese Medicine Analysis
  • Traditional Chinese Medicine Studies
  • Pharmacological Effects of Natural Compounds
  • Complementary and Alternative Medicine Studies
  • Medical Research and Treatments
  • Cancer-related molecular mechanisms research
  • Medicinal Plant Pharmacodynamics Research
  • Acupuncture Treatment Research Studies
  • Menstrual Health and Disorders
  • Medicinal plant effects and applications
  • RNA modifications and cancer
  • Radioactivity and Radon Measurements
  • Bone Tissue Engineering Materials
  • Nanoparticles: synthesis and applications
  • Plant-based Medicinal Research
  • Phytochemical Studies and Bioactivities
  • Phytochemicals and Antioxidant Activities
  • Radiation Detection and Scintillator Technologies
  • COVID-19 Clinical Research Studies
  • Periodontal Regeneration and Treatments
  • Lipid metabolism and disorders
  • Genetics, Aging, and Longevity in Model Organisms
  • Immune Response and Inflammation
  • Computational Drug Discovery Methods
  • SARS-CoV-2 and COVID-19 Research

University of South China
2019-2023

Renji Hospital
2021-2022

Shanghai Jiao Tong University
2022

First Affiliated Hospital of Guangzhou University of Chinese Medicine
2020-2022

Hainan Medical University
2022

Yangzhou University
2021

Beijing Hospital of Traditional Chinese Medicine
2020

Capital Medical University
2020

Guangzhou University of Chinese Medicine
2020

Chenzhou First People's Hospital
2016-2020

Background: Plant essential oils have long been regarded as repositories of antimicrobial agents. In recent years, they emerged potential alternatives or supplements to drugs. Although literature reviews and previous studies indicated that cinnamon oil (CIEO) its major component, cinnamaldehyde (CID), possess potent antibacterial activities, their mechanisms, especially the in vivo remain elusive. Methods: this study, we utilized assessment system Caenorhabditis elegans ( C. ) investigate...

10.3389/fphar.2024.1378434 article EN cc-by Frontiers in Pharmacology 2024-03-11

The purpose of this study was to elucidate the expression long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3) in rats with Alzheimer's disease (AD) and explore its potential mechanisms.An AD rat model induced by microinjection Aβ25-35 . On first day after successful modeling, pcDNA3.1 plasmid pcDNA3.1-MEG3 were continuously infused into third ventricle through a micro-osmotic pump interfere level MEG3. spatial learning ability memory ability, histopathological changes hippocampus...

10.1002/jcb.29108 article EN Journal of Cellular Biochemistry 2019-06-12

The purpose of this study was to design and characterise a novel biomimetic scaffold for the repair critical size calvarial defects.

10.1039/c6ra02038k article EN RSC Advances 2016-01-01

Depression is a complex mental disorder, affecting approximately 280 million individuals globally. The pathobiology of depression not fully understood, and the development new treatments urgently needed. Dihydromyricetin (DHM) natural flavanone, mainly distributed in Ampelopsis grossedentata. DHM has demonstrated protective role against cardiovascular disease, diabetes, liver cancer, kidney injury neurodegenerative disorders. In present study, we examined effect chronic mouse model induced...

10.3390/cells11233730 article EN cc-by Cells 2022-11-22

Background: Coronavirus disease (COVID-19) seriously endangers global public health. Pupingqinghua prescription (PPQH) is an herbal formula from traditional Chinese medicine used for treatment of SARS-CoV-2 infection. This study aims to evaluate the clinical efficacy and safety PPQH in participants infected with Omicron variant. Methods: A total 873 (Omicron)-infected patients were included. Among them, divided into group (653 cases) LHQW (220 according different medications. The...

10.3389/fphar.2022.988524 article EN cc-by Frontiers in Pharmacology 2022-10-07

To realize the retrospective measurement of public dose levels after a nuclear emergency, optically stimulated luminescence radiation dose-response characteristics salt were studied, and relationship between signal ionizing was determined. The effects natural light, storage time, preheating temperature on examined. results show that as photoluminescence material has advantages convenient sampling, high throughput, short detection wide range, low limit. study lays technical foundation for...

10.2298/ntrp2303169h article EN cc-by-nc-nd Nuclear Technology and Radiation Protection 2023-01-01

To observe the effects of electroacupuncture at bilateral Zusanli(ST36), Shangjuxu(ST37), and Sanyinjiao (SP6) acupoints on gastrointestinal function after laparoscopic cholecystectomy under general anesthesia.A total 150 patients(American Society Anesthesiologists[ASA] grades Ⅰ Ⅱ) undergoing in Department Hepatobiliary Surgery First Affiliated Hospital Guangzhou University Chinese Medicine were randomly assigned into three groups: group (n=50), simple acupuncture control (n=50). Patients...

10.13702/j.1000-0607.20210711 article EN PubMed 2022-07-25

Abstract In this study, a simple and reliable LC–MS/MS method was first proposed for the simultaneous determination of TUG‐891 its metabolites TUG‐891‐alcohol, TUG‐891‐aldehyde, TUG‐891‐acid in rat plasma. The analytes fasiglifam (internal standard) were extracted from plasma samples with acetonitrile separated using an Acquity BEH C 18 column (1.7 μm, 2.1 × 50 mm) water containing 0.05% ammonium hydroxide as mobile phase. A Q‐Exactive Orbitrap mass spectrometer full‐scan mode used...

10.1002/bmc.4870 article EN Biomedical Chromatography 2020-04-29

To aim directly at the research status of Chinese drugs pharmaceutics, this study provides a new idea "traditional medicine multiple drug delivery system based on material basis component". This thought according to whole concept, syndrome, and characteristics multi-component, multi-target, multi-effect. The premise designing traditional is component, purpose improve bioavailability. example multi-drug tongmai micro-pellets expounded for application. model pharmaceutics strategies methods...

10.4268/cjcmm20121433 article EN China Journal of Chinese Materia Medica 2012-07-15

In response to the increasingly serious aging problem and demand for intelligent home care, this paper adopts Internet of Things technologies such as RFID indoor positioning sensors achieve real-time monitoring status elderly people at home. The system can monitor dangerous location or actions in by obtaining information from tags sensors, respond, reminding personnel, notifying police stations, children elderly, etc. also provide assistance services regularly take medication going hospital...

10.1109/eiect60552.2023.10442016 article EN 2023-11-17

Abstract Background To clarify the historical views on disease name, etiology and pathogenesis for Gastroesophageal reflux (GERD) in ancient Traditional Chinese Medicine (TCM). Methods A comprehensive literature search was performed < Zhong Hua Yi Dian > database with keywords ‘Acid regurgitation’, ‘Epigastric upset’ ‘Bilious vomiting’. All information about names, were included extracted by two independent reviewers. The Citespace software used data analysis. After importing purging,...

10.21203/rs.3.rs-132202/v1 preprint EN cc-by Research Square (Research Square) 2020-12-22
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