- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiovascular Effects of Exercise
- Cardiovascular Disease and Adiposity
- Atherosclerosis and Cardiovascular Diseases
- Salivary Gland Tumors Diagnosis and Treatment
- Aortic Thrombus and Embolism
- Coronary Artery Anomalies
- Tracheal and airway disorders
- Ear and Head Tumors
- Systemic Lupus Erythematosus Research
- Peripheral Neuropathies and Disorders
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
The Royal Melbourne Hospital
2013-2023
The University of Melbourne
1997-2022
University of Oxford
2019
The University of Adelaide
2014
Royal Adelaide Hospital
2007-2014
The Alfred Hospital
2014
Cedars-Sinai Kerlan-Jobe Institute
2010
University of Rochester Medical Center
2010
Austin Hospital
2007
Monash Medical Centre
2007
To characterize the nature of atrial fibrillation (AF) activation in human persistent AF (PerAF) using modern tools including activation, directionality analyses, complex-fractionated electrogram, and spectral information. The mechanism PerAF humans is uncertain. High-density epicardial mapping (128 electrodes/6.75 cm2) posterior LA wall (PLAW), RA appendage (LAA, RAA), RSPV-LA junction was performed 18 patients with undergoing open heart surgery. Continuous 10 s recordings were analysed...
Background— The pulmonary vein–left atrial (PV–LA) junction is key in pathogenesis of AF, and acute stretch an important stimulus to AF. We aimed characterize the response stretch, hypothesizing that would result electrophysiological changes predisposing re-entry. Methods Results— Fifteen participants undergoing cardiac surgery underwent evaluation right superior PV–LA using epicardial mapping plaque. In 10, this was performed before after imposed by rapid volume expansion, 5, it with...
The Ross procedure has demonstrated excellent results when performed in patients with aortic stenosis or mixed valve disease [aortic and regurgitation (AR)]. However, due to its reported risk of late reoperation, it is not recommended under current guidelines for presenting bicuspid pure AR. We have analysed our own light this recommendation. Between 1993 2016, 129 consecutive a mean age 34.7 ± 10.6 years (range 16–64 years) presented AR underwent the procedure. Patients were reviewed...
Endocardial-epicardial dissociation and focal breakthroughs in humans with atrial fibrillation (AF) have been recently demonstrated using activation mapping of short 10-second AF segments. In the current study, we used simultaneous endo-epi phase to characterize patterns on long segments human persistent AF.Simultaneous intraoperative endo- epicardial lateral right atrium wall was performed patients 2 high-density grid catheters (16 electrodes, 3 mm spacing). Filtered unipolar bipolar...
Double mitral and aortic mechanical valves present an access challenge when planning a ventricular tachycardia (VT) ablation. In this case report, we describe patient who was considered for stereotactic ablative radiotherapy but unable to proceed due unfavorable anatomy making them at high risk of fistula formation. The went on have endocardial VT ablation via mini-thoracotomy transapical without complication. This highlights the need careful consideration treatment patients with double valves.