A5052879589- Glaucoma and retinal disorders
- Corneal surgery and disorders
- EEG and Brain-Computer Interfaces
- Ocular Surface and Contact Lens
- Heart Rate Variability and Autonomic Control
- Vagus Nerve Stimulation Research
- Neurological disorders and treatments
- Retinal and Macular Surgery
- Neuroscience and Neural Engineering
Johns Hopkins University
2021-2022
Purdue University West Lafayette
2019
Abstract Continuous monitoring of intraocular pressure, particularly during sleep, remains a grand challenge in glaucoma care. Here we introduce class smart soft contact lenses, enabling the continuous 24-hour even sleep. Uniquely, lenses are built upon various commercial brands without altering their intrinsic properties such as lens power, biocompatibility, softness, transparency, wettability, oxygen transmissibility, and overnight wearability. We show that can seamlessly fit across...
We present a wireless, fully implantable device for electrical stimulation of peripheral nerves consisting powering coil, tuning network, Zener diode, selectable parameters, and stimulator IC, all encapsulated in biocompatible silicone. A wireless RF signal at 13.56 MHz powers the implant through on-chip rectifier. The ASIC, designed TSMC's 180 nm MS G process, occupies an area less than 1.2 mm2. IC enables externally current-controlled read-only memory with wide range 32 parameters (90-750...
Heart disease is the leading cause of death worldwide. Hypertension an important precursor and most common risk factor to heart failure. While some patients can control their high blood pressure with pharmaceuticals, many suffer from resistant hypertension, where antihypertensive medications do not achieve desired outcome. Electrical stimulation emerging therapy modulate integrating it closed-loop feedback improve control.We design fabricate two application-specific integrated circuits...
Current minimally-invasive glaucoma surgery (MIGS) devices promise to control elevated levels of intraocular pressure (IOP) while avoiding many the downsides traditional surgery. However, there remains room for improvement in performance metrics, including drainage efficacy, device longevity, and time implant, as outlined by benchmarks set forth Audacious Goals Initiative. We introduce a better shunt, which achieves similar or improved pre-clinical safety efficacy outcomes commercial MIGS...