A5023409938- Advanced biosensing and bioanalysis techniques
- Hearing, Cochlea, Tinnitus, Genetics
- Metabolomics and Mass Spectrometry Studies
- Electrospun Nanofibers in Biomedical Applications
- Polysaccharides and Plant Cell Walls
- Agriculture and Biological Studies
- Traditional Chinese Medicine Analysis
- Semiconductor Lasers and Optical Devices
- Polysaccharides Composition and Applications
- Olfactory and Sensory Function Studies
- Ginkgo biloba and Cashew Applications
- Phytochemicals and Antioxidant Activities
- Traditional Chinese Medicine Studies
- Antibiotic Resistance in Bacteria
- Phytochemistry and biological activities of Ficus species
- Modular Robots and Swarm Intelligence
- DNA and Biological Computing
- Hydrogels: synthesis, properties, applications
- Phytoestrogen effects and research
- Connexins and lens biology
- Cell Image Analysis Techniques
- Boron and Carbon Nanomaterials Research
- Bacteriophages and microbial interactions
- Ear Surgery and Otitis Media
- Neuroinflammation and Neurodegeneration Mechanisms
Zhejiang University
2004-2025
Second Affiliated Hospital of Xi'an Jiaotong University
2016-2025
Ningxia University
2025
Soochow University
2024
Fujian University of Traditional Chinese Medicine
2012-2024
Fujian Academy of Medical Sciences
2022-2024
First Affiliated Hospital Zhejiang University
2022-2024
Suizhou Central Hospital
2024
West China Second University Hospital of Sichuan University
2020-2023
Sichuan University
2007-2023
The average measured Hv for polycrystalline ReB2 and Ti–B composites under different loads shows that the tendency of to decrease becomes weak large loads, hardness is always lower than composites. For comparison, results from Chung et al. were inserted into figure.
Glycogen synthase kinase-3 (GSK-3), a Ser/Thr protein kinase abundantly expressed in neurons, plays diverse functions physiological and neurodegenerative conditions. Our recent study shows that upregulation of GSK-3 suppresses long-term potentiation presynaptic release glutamate; however, the underlying mechanism is elusive. Here, we show activation GSK-3β retards synaptic vesicle exocytosis response to membrane depolarization. Using calcium imaging, whole-cell patch-clamp, as well specific...
The aims of this study were to evaluate the antidiabetic activity and detect molecular size Pseudostellaria heterophylla polysaccharide (PHP). is a medicine extensively used in traditional Chinese formulas treat diabetes its complications. Molecular weight PHP was determined by gel permeation chromatography combined with phenol-sulphuric acid method monosaccharides composition HPLC precolumn derivatization. Four polysaccharides different compared for hypoglycemic active on two animal models...
Pseudostellaria heterophylla (Miq.) Pax is one of the most widespread herbal and healthcare products in China. Extensive clinical use has shown that it functions which “strengthens qi generates saliva, moistens lung relieves cough”. The ethyl acetate fraction extracted from roots plant exhibited a dose-dependent antitussive effect between 100 to 500 mg/kg. At dose 400 mg/kg, treatment markedly prolonged cough latent period reduced number coughs guinea pig model induced by citric acid. Fall...
BACKGROUND: Immune rejection can lead to the failure of human embryonic stem cell (hES cell) transplantation. One approach address problem is establish hES line banks. Due limited source embryos and ethical reasons, lines are not readily available. This study was undertaken determine whether discarded day 3 with low morphological scores could develop into blastocysts produce lines. METHODS: A total 130 were cultured blastocyst stage, inner masses (ICM) isolated by immunosurgery. Colonies...
To analyze the clinical characteristics and outcomes of carbapenem-resistant Klebsiella pneumoniae (CRKp) carbapenem-susceptible K. (CSKp) bloodstream infections (BSIs), to study risk factors for development CRKp BSI BSI-related mortality.A retrospective case control patients with was conducted in intensive care unit First Affiliated Hospital, Medical College, Zhejiang University from January 2013 December 2014. Carbapenem resistance defined accordance Clinical Laboratory Standards Institute...
Abstract Aquaculture is a fast‐growing and rapidly expanding industry in the world. Probiotics are widely used aquaculture have provided benefits to aquatic animal health, it also promising alternative antibiotics for control of fish diseases. With development biotechnology, new expression systems novel techniques surface display heterologous proteins probiotics cells been developed. This review provides an overview strategies displaying functional on commonly aquaculture, which Bacillus...
Abstract Polysaccharide (PF40) has been recognized as a main bioactive substances in Pseudostellaria heterophylla (Miq.). The current study explored the potential protective effects of PF40 on immune system mice with cyclophosphamide‐induced immunosuppression. were intragastric administered at dosage 100, 200 or 400 mg/kg once daily for 30 days, On 24th and 25th day, additional intraperitoneal injection (50 mg/kg) administered. results showed that enhanced cell‐mediated immunity via...
The semi-refined polysaccharide of Pseudostellaria heterophylla is a complex that exhibits significantly hypoglycemic activities. A novel homogeneous polysaccharide, named as H-1-2, was isolated from the polysaccharide. mean molecular weight H-1-2 1.4 × 104 Da and it only composed d-glucose monosaccharide. Structure elucidation indicated contains pyranride, has characteristics α-iso-head configuration, non-reducing end (T-), 4-, 1,6-, 1,4,6-connection, in all four ways to connect glucose....
Sepsis-associated encephalopathy (SAE) is a common complication of severe sepsis. Some studies have suggested that P2X7 receptors, ligand-gated ion channel receptor subgroup activated by extracellular ATP, plays an important role in cell pyroptosis. However, the receptors development SAE with pyroptosis and its pathways are still unclear. In this study, we established juvenile rat model sepsis cecal ligation perforation, showed there was significant increase expression cortex rats When...
This study aimed to investigate the Pseudostellaria heterophylla polysaccharides (PF40) physicochemical and antidiabetic characteristics. The ultraviolet-visible (UV) spectra, Fourier transform infrared radiation (FT-IR) nuclear magnetic resonance (NMR) zeta potential, surface characteristics, conformational thermal stability properties of PF40 were characterized. X-ray diffraction (XRD) scanning electron microscopy (SEM), combined with Congo red test, revealed that powder has mainly existed...
Abstract Pseudostellaria heterophylla , also called Tai-zi-shen (TZS) in Traditional Chinese Medicine (TCM), is always used clinically to treat spleen deficiency symptoms. Polysaccharides TZS have various pharmacological activities, including anti-diabetic, immune regulation, and myocardial protection. However, the relationship between spleen-invigorating effects of or its polysaccharides intestinal flora are not clear. This study investigated decoction (PHD) polysaccharide (PHP) on function...
Abstract The jet stretch of wet‐spun PAN fiber and its effects on the cross‐section shape properties fibers were investigated for PAN‐DMSO‐H 2 O system. Evidently, spinning parameters, such as dope temperature, bath concentration, influenced stretch. Also, under uniform conditions, postdrawing ratio changed well that When coagulation temperature was 35°C simultaneously with concentration 70%, impacted obviously shapes fiber, but had little effect when below 10°C or above 70°C. As increased,...