A5100331167- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Blood groups and transfusion
- Gastrointestinal motility and disorders
- Erythrocyte Function and Pathophysiology
- Asthma and respiratory diseases
- Anomaly Detection Techniques and Applications
- Chronic Myeloid Leukemia Treatments
- Complementary and Alternative Medicine Studies
- Brain Metastases and Treatment
- Software System Performance and Reliability
- Epigenetics and DNA Methylation
- Radiomics and Machine Learning in Medical Imaging
- Glioma Diagnosis and Treatment
- Ocular and Laser Science Research
- Monoclonal and Polyclonal Antibodies Research
- Intraocular Surgery and Lenses
- Hemoglobinopathies and Related Disorders
- Ginger and Zingiberaceae research
- Network Security and Intrusion Detection
- Immune Cell Function and Interaction
- Radiopharmaceutical Chemistry and Applications
- Diverse Approaches in Healthcare and Education Studies
- Advanced Optical Sensing Technologies
Tongji University
2019-2024
Shanghai University of Traditional Chinese Medicine
2023-2024
Shanghai Pulmonary Hospital
2019-2024
Zhejiang Center for Disease Control and Prevention
2024
Shenzhen University Health Science Center
2023
Beijing Technology and Business University
2023
Peking University
2016-2023
Peking University Cancer Hospital
2023
Shandong University
2023
Guangzhou University of Chinese Medicine
2023
Oral drug delivery is the most attractive pathway for ulcerative colitis [UC] therapy, since it has many advantages. However, this strategy encountered challenges, including instability of drugs in gastrointestinal tract [GT], low targeting disease tissues, and severe adverse effects. Nanoparticles capable tissue-targeted site-specific release may offer a unique therapeutically effective system that addresses these formidable challenges. We used versatile single-step surface-functionalising...
A novel double light-scattering-layer ZnO (DL-ZnO) film consisting of monodisperse aggregates (MA-ZnO) as underlayer and sub-micrometer-sized platelike (SP-ZnO) overlayer was fabricated studied dye-sensitized solar-cell photoanodes. It found that DL-ZnO could significantly improve the efficiency solar cells (DSSCs) owing to its relatively high surface area enhanced light-scattering capability. The overall energy-conversion (η) 3.44% achieved by formation film, which is 47% higher than formed...
Fault localization is challenging in an online service system due to its monitoring data's large volume and variety complex dependencies across/within components (e.g., services or databases). Furthermore, engineers require fault solutions be actionable interpretable, which existing research approaches cannot satisfy. Therefore, the common industry practice that, for a specific system, experienced focus on recurring failures based knowledge accumulated about historical failures. More...
Background: Non-small cell lung cancer (NSCLC) remains the first leading cause of death in malignancies worldwide. Despite early screening NSCLC by low-dose spiral computed tomography (CT) high-risk individuals caused a 20% reduction mortality, there still exists imperative needs for identification novel biomarkers diagnosis and treatment cancer. Methods: mRNA microarray datasets GSE19188, GSE33532, GSE44077 were searched, differentially expressed genes (DEGs) obtained using GEO2R....
In large-scale online service system, to enhance the quality of services, engineers need collect various monitoring data and write many rules trigger alerts. However, number alerts is way more than what on-call can properly investigate. Thus, in practice, are classified into several priority levels using manual rules, primarily focus on handling with highest level (i.e., severe alerts). Unfortunately, due complex dynamic nature this rule-based approach results missed or wasted...
Inflammatory reaction in the brain activates glial cells, and over-activated cells secrete inflammatory mediators, which aggravates response accelerates development of Alzheimer's disease (AD) turn. Numerous natural compounds from herbs can alleviate inflammation, it is very promising to find anti-neuroinflammatory compounds. Micheliolide (MCL) an asesquiterpene lactone. Studies have proved that MCL showed obvious anti-inflammatory property. Nevertheless, whether treat AD has not been...
Bone marrow abnormalities are frequently observed in HIV-1-infected individuals. Infection of mesenchymal stem cells (MSCs) may abrogate their growth properties and hematopoietic supportive functions. To delineate the cell type infected, factors responsible for deleterious effects, human bone were exposed to HIV-1 vitro. By week 4, ability MSCs form colonies purely fibroblasts (CFU-F) mixed adipocytes (CFU-FA) was suppressed by 23 +/- 5 55 7%, respectively. The p24 concentration culture...
Conventional stabilization/solidification materials have defects in the simultaneous treatment of heavy metals (HMs) and phenanthrene (PHe). In order to solve this problem, a new functional material β-cyclodextrin modified biochar (β-CD-BC) was prepared by integrating properties (BC) hydrophilic hydrophobic β-CD surface combined with Portland cement (PC) cure stabilize HMs PHe. The effect key parameters on discussed response method. results showed that minimum leaching concentration if 16.81...
Incidents in online service systems could incur poor user experience and tremendous economic loss. To reduce the influence of incidents guarantee reliability, it is critical to identify root-cause metrics for engineers with clues assist incident diagnosis. However, a challenging task due complicated dependencies huge volume various large-scale systems. Existing approaches are based on either anomaly detection or correlation analysis, performing not well terms accuracy efficiency. better...
BACKGROUND Anti‐E is the most common and important RBC alloantibody in Chinese population. Several studies have demonstrated that production of specific alloantibodies associated with HLA‐DRB1 polymorphisms. Considering population has its own unique characteristics polymorphisms, we investigate whether alleles are E immunization a STUDY DESIGN AND METHODS The frequencies phenotypes were compared among 78 patients possessing anti‐E 192 healthy blood donors. genotyping was carried out using...
Achyranthes bidentata is one of the most commonly used Chinese herbal medicines (CHM) that currently considered for treatment osteoarthritis. The purpose this study was to reveal mechanism in osteoarthritis based on network pharmacology.The effective components were firstly screened out from TCMSP database with ADME property parameters. Then, osteoarthritis-related proteins targeted by predicted DrugBank and CTD databases. Subsequently, enrichment analysis interaction between targets...
To explore the reason and treating method for negative value of uric acid in a patient patient.The serum with detection was diluted 5 times "sterilized water" "normal saline". Additionally, treated PEG6000 protein, detected.Elevated IgM paraprotein resulted abnormal response curves samples or samples. After precipitated PEG600, curve basically normal.The patient's test caused by paraprotein. removing interference protein true accurate result obtained.
Brain metastases (BM) of lung adenocarcinoma (LUAD) are the most common intracranial malignancy leading to death. However, cellular origins and drivers BM from LUAD have not been clarified. Cellular composition was characterized by single-cell sequencing analysis primary (pLUAD), lymph node metastasis (LNM) samples in GSE131907. Our study briefly analyzed tumor microenvironment (TME), focusing on role epithelial cells (ECs) BM. We discovered a population brain metastasis-associated (BMAECs)...
Background: Cancer patients who receive anthracycline-based chemotherapy regimens often discontinue due to cardiotoxicity. Preventing and reducing anthracycline-induced cardiotoxicity (ACT) is a hot topic in cardio-oncology research. Network pharmacology new discipline that integrates pharmacology, bioinformatics, systems biology. It can be used analyze the mechanism of action drugs body from holistic perspective by constructing "disease-gene-drug" network, providing method explore...
Traditional Chinese medicine (TCM) makes a synergistic and attenuative effect when combined with chemoradiotherapy. However, strong evidence-based studies are lacking. The study sought to investigate whether Zengxiao Jiandu decoction as an adjunctive therapy is superior definitive concurrent chemoradiotherapy (DCCRT) alone in unresectable, locally advanced (LA), stage III non-small cell lung cancer (NSCLC).Patients unresectable LA-NSCLC were randomly assigned receive DCCRT either (TCM arm)...