A5103007874- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Stress Responses and Cortisol
- Cancer Immunotherapy and Biomarkers
- Virus-based gene therapy research
- Crystallization and Solubility Studies
- Cancer Genomics and Diagnostics
- X-ray Diffraction in Crystallography
- Brain Metastases and Treatment
- Cancer-related molecular mechanisms research
- Helicobacter pylori-related gastroenterology studies
- Ferroptosis and cancer prognosis
- Tryptophan and brain disorders
- Cytokine Signaling Pathways and Interactions
- Nanoparticle-Based Drug Delivery
- Circular RNAs in diseases
- RNA modifications and cancer
- Genetic factors in colorectal cancer
- Viral Infectious Diseases and Gene Expression in Insects
- Neuroinflammation and Neurodegeneration Mechanisms
- Curcumin's Biomedical Applications
- Cancer Cells and Metastasis
- Crystallography and molecular interactions
- Viral gastroenteritis research and epidemiology
Hubei Academy of Forestry
2024-2025
Guangxi University of Finance and Economics
2024
Shanghai Chest Hospital
2018-2024
Shanghai Jiao Tong University
2018-2024
Centers for Disease Control and Prevention
2024
Wuhan City Chinese Medicine Hospital
2024
Cancer Hospital of Chinese Academy of Medical Sciences
2024
Zhejiang Cancer Hospital
2024
University of Chinese Academy of Sciences
2024
Hebei University
2024
Yellow horn grows in northern China and has a high tolerance to drought poor soil. Improving photosynthetic efficiency increasing plant growth yield under conditions have become important research content for researchers worldwide. Our study goal is provide comprehensive information on photosynthesis some candidate genes breeding of yellow stress. In this study, seedlings’ stomatal conductance, chlorophyll content, fluorescence parameters decreased stress, but non-photochemical quenching...
The relationship between circular RNA (circRNA) and cancer stem cells (CSCs) is uncertain. We have investigated the combined influence of CSCs, circRNA (hsa_circ_0003222), immune checkpoint inhibitors in NSCLC progression therapy resistance. constructed lung CSCs (LCSCs; PC9 A549). effects hsa_circ_0003222 vitro were determined by cell counting, colony sphere formation, Transwell assays. A tumor xenograft model metastasis orthotopic built for vivo analysis. found that was highly expressed...
The biological role and clinical significance of transfer RNA-derived small RNAs (tsRNAs) remain largely unclear. purpose this study was to investigate the function, molecular mechanism, tsRNA-5001a in lung adenocarcinoma.The function on growth tumor cells accessed by cell experiments. Real-time quantitative polymerase chain reaction (RT-qPCR) used detect expression paired samples adenocarcinoma. Cell localization performed nuclear-cytoplasmic separation assay. Transcriptome sequencing...
Long noncoding RNAs (lncRNAs) regulate the progression of type 2 diabetes mellitus complicated with obstructive sleep apnoea (T2DM-OSA). However, role lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1) in T2DM-OSA remains unknown. This study aimed to reveal function NEAT1 and underlying mechanism. KKAy mice were exposed intermittent hypoxia (IH) or normoxia generate a mouse model. HMEC-1 cells treated high glucose (HG) IH construct cell RNA expression was detected by qRT-PCR. The...
Abstract Background Human adenoviruses (HAdVs) can cause outbreaks of flu-like illness in university settings. Most infections healthy young adults are mild; severe illnesses rarely occur. In Fall 2022, an adenovirus outbreak was identified students. Methods HAdV cases were defined as students 17–26 years old who presented to the University Health Service or nearby emergency department with symptoms (eg, fever, cough, headache, myalgia, nausea) and had confirmed by polymerase chain reaction...
Background Combining immune checkpoint inhibitors (ICIs) with chemotherapy has become a standard treatment for patients non-small cell lung cancer (NSCLC) lacking driver gene mutations. Reliable biomarkers are essential predicting outcomes. Emerging evidence from various cancers suggests that early assessment of serum metabolites could serve as valuable This study aims to identify linked outcomes in advanced NSCLC undergoing first-line or second-line therapy programmed death 1 (PD-1) plus...
Abstract Drought is one of the main environmental factors affecting plant survival and growth. Atraphaxis bracteata a common desert mainly utilized in afforestation desertification control. This study analyzed morphological, physiological molecular regulatory characteristics different organs A. under drought stress. The results showed that with intensification stress, height, root length leaf area seedlings decreased, while content osmotic substances antioxidant enzyme activity increased....
Background Unlike lung adenocarcinoma, patients with advanced squamous carcinoma exhibit a low proportion of driver gene positivity, fewer effective treatment strategies available. Chemoimmunotherapy has now become the standard first-line for individuals diagnosed carcinoma. Serum metabolomics holds significant potential application in predicting responses to chemoimmunotherapy and is capable identifying validating biomarkers. The aim our study was establish model that can predict prognosis...
A significant association between high blood-based tumor mutational burden (bTMB) and improved progression-free survival (PFS) was observed in advanced non-small cell lung cancer (NSCLC) receiving atezolizumab. However, this result unrepeatable a recent prospective study. We hypothesized that there might be non-linear bTMB survival. This study used the clinical genetic data from POPLAR (n = 105, training set) OAK 324, validation trials. The assessed using restricted cubic spline (RCS)....