A5076402497- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Sleep and related disorders
- Retinal Development and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Traumatic Ocular and Foreign Body Injuries
- Photoreceptor and optogenetics research
- Ocular Disorders and Treatments
- Diagnosis and Treatment of Venous Diseases
- Health and Wellbeing Research
- Cytomegalovirus and herpesvirus research
- Contact Dermatitis and Allergies
- Optical Coherence Tomography Applications
- Genetic and Kidney Cyst Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Circadian rhythm and melatonin
- Drug-Induced Adverse Reactions
- Neurological Disorders and Treatments
- Genetic Syndromes and Imprinting
- Nasal Surgery and Airway Studies
- Ocular Infections and Treatments
- Facial Nerve Paralysis Treatment and Research
Sandwell & West Birmingham Hospitals NHS Trust
2014-2021
John Radcliffe Hospital
2021
Birmingham and Midland Eye Centre
2011-2021
NIHR Surgical Reconstruction and Microbiology Research Centre
2017-2019
University Hospitals Birmingham NHS Foundation Trust
2014-2019
Oxford University Hospitals NHS Trust
2012-2019
Queen Elizabeth Hospital Birmingham
2018
Solihull Hospital
2017
University of Oxford
2014-2016
Nuffield Foundation
2014
To compare visual function and structural improvements in pseudophakic eyes with diabetic macular oedema (DMO) treated the 0.19mg Fluocinolone Acetonide (FAc) intravitreal implant (IluvienTM) a 'real world' setting.A single centre retrospective evaluation of patients DMO unresponsive to conventional treatment FAc according UK guidelines. Primary efficacy endpoint was best corrected acuity (BCVA); secondary endpoints included optical coherence tomography evaluations macula (a) central retinal...
Purpose: Diabetic retinopathy (DR) is associated with retinal neuronal and vascular damage. DR has previously been shown to affect the photosensitive ganglion cells (pRGCs). PRGCs are essential for entrainment of circadian rhythms; thus, progression could lead worsening sleep quality mood. We investigate relationship between increasing severity, its impact on Methods: A total 430 participants DR, 303 healthy controls no ocular disease or preexisting disorders were recruited. severity was...
Previous studies have shown that patients with diabetic macular edema (DME) relatively good visual acuity can slow reading speed. The aim of this study was to evaluate the structural-functional correlation in a cohort DME and assess whether central four retinal points on microperimetry (MP4) could be used as potentially faster more reliable method assessing function than speed.The performed clinically significant DME. best-corrected (BCVA) recorded letter counting modified ETDRS chart,...
Pegaptanib has been shown to be effective in treating diabetic macular edema (DME). In the original Phase II/III trial, however, patients with ischemia were excluded. this study, we treated ischemic DME.Macular was defined as a 30% increase area of foveal avascular zone (FAZ) at 45 seconds on fundus fluorescein angiography. addition, participants had diffuse foveal-involving DME central subfield thickness (CST) >300 μm spectral-domain optical coherence tomography. Five intravitreal...
We report a rare presentation of acute bilateral peripheral ulcerative keratitis (PUK) in patient with new diagnosis untreated myeloid leukaemia (AML). To the best our knowledge, this is first PUK associated AML and we stress importance rapid thorough testing to exclude other diagnoses. The lost his vision within 10 days counting fingers. Rapid allowed good visual recovery following prompt treatment oral steroids systemic chemotherapy for AML.
We report a case of retinal artery occlusion in young adult early pregnancy found to have patent foramen ovale as the source embolism. This suggests importance cardiac investigation such individuals.
Purpose: To compare retinal sensitivity and central thickness in patients with focal diabetic macular edema (DME) secondary to branch vein occlusion (BRVO). Methods: In this consecutive, cross-sectional, observational study, either DME or BRVO underwent measurements for best-corrected visual acuity, microperimetry, spectral domain optical coherence tomography. Retinal were measured using Optos Spectral tomography/scanning laser ophthalmoscopy (Optos plc, Dunfermline, Scotland, United...
Vitamin A deficiency is increasing. Early identification of high-risk patients and rapid treatment can prevent potentially fatal blinding complications.
A 67 year old woman attended the day surgery for routine cataract surgery. She had no previous ocular complaints. During peribulbar anaesthesia a bluish foreign body emerged from …
The aim of this study was to compare measurements macular thickness, obtained from patients with diabetic edema, using two spectral-domain optical coherence tomography (SD-OCT) devices. These were the Spectralis Heidelberg Retina Angiograph + Optical Coherence Tomography (HRA OCT) (Heidelberg Engineering), which is often considered gold-standard for OCT measurement, and Spectral Tomography/Scanning Laser Ophthalmoscopy (OCT/SLO) (Optos plc), can additionally perform microperimetry, a useful...
Background: Before highly active antiretroviral therapy, cytomegalovirus (CMV) retinitis was a major threat to vision in individuals with HIV. We investigate whether ophthalmic screening of asymptomatic HIV patients still has value the therapy era and consider CD4 thresholds line world literature UK experience. Methods: A retrospective chart review conducted all seen by Ophthalmic Service university hospital both before (2007–2008) after (2011–2012) introduction threshold lower than 100...
Light plays a critical role in regulating physiology and behavior, including both visual non-visual responses. In mammals, loss of eyes abolishes all these responses, demonstrating that the photoreceptors involved are exclusively ocular. By contrast, many non-mammalian species possess extra-ocular located pineal complex deep brain. Whilst there have been suggestions photoreception man, evidence for is limited. One approach to objectively determine presence such receptors measure brain...
A 38-year-old woman presented to casualty with bilateral red eyes associated a recent upper respiratory tract infection. This was initially diagnosed as conjunctivitis, however systemic review revealed an erythematous facial and skin rash, mildly swollen lips mild swallowing difficulties. The patient referred for urgent medical assessment, by which time she found have erythema affecting 54% of her body surface area suspected toxic epidermal necrolysis (TEN). She rapidly deteriorated over 24...