A5059163233- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Immune Cell Function and Interaction
- Hepatitis B Virus Studies
- HIV/AIDS drug development and treatment
- Hepatitis C virus research
- Pharmaceutical studies and practices
- Pharmaceutical Practices and Patient Outcomes
- Platelet Disorders and Treatments
- Blood properties and coagulation
- Blood groups and transfusion
- T-cell and B-cell Immunology
- Liver Disease Diagnosis and Treatment
- Innovations in Medical Education
- interferon and immune responses
Florida College
2019-2020
Auburn University
2020
University of South Florida
2019-2020
Presbyterian College
2020
University of Maryland, Baltimore
2020
The University of Texas at Tyler
2020
University of North Texas
2020
University of North Texas System
2020
University of North Texas Health Science Center
2020
Rutgers, The State University of New Jersey
2020
We identified two genes induced by type 1 interferon in activated CD4 + T cells that are associated with HIV restriction humans.
To assess if the reduction in HIV-1 RNA CD4 T cells is correlated with persistence of immune activation following early antiretroviral therapy (ART).Clinical trial (NCT01285050).Next-generation sequencing was used to study total from activated (CD38 and human leukocyte antigen - D related (HLA-DR) expressing) collected 19 treatment-naïve HIV-1/hepatitis C virus-infected patients before after ART initiation (≥12 weeks plasma <50 copies/ml). validate comparisons, pre post-ART measures were...
Abstract Type 1 interferons upregulate many interferon-stimulated genes (ISGs) with diverse antiviral effects. ISGs that restrict HIV in humans have been poorly characterized. Exogenous interferon-α decreases viremia: we hypothesized induces expression of anti-HIV activity activated CD4+ T cells, the cells which chiefly replicates. Activated (CD3+/CD4+/CD38+/HLA-DR+) were sorted from PBMCs taken 19 infected patients uncontrolled viremia before and after peginterferon alpha 2b (IFN)...
Thrombocytopenia and other hematologic manifestations related to HIV are not uncommon. Treatment of HIV-related thrombocytopenia is challenging: treatment options effective in all patients, or less well studied, particularly the pediatric population. We aim present discuss case a 13-year-old with persistent who, after failing monthly IVIG infusions, showed normalization platelet count on novel thrombopoietin receptor agonist, eltrombopag. A retrospective chart review patient's medical record...
Experiential education conducted in the pediatric practice setting provides student pharmacists opportunity to learn about a unique patient population. For many students, experiential rotations may be only form of they receive pharmacy school. Providing quality experiences is essential stimulate students' interest this area and train those with goals become pharmacists. It also important ensure graduating have exposure fundamental concepts. Although areas institutions differ populations...