A5049971556- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Neurosurgical Procedures and Complications
- Meningioma and schwannoma management
- Stroke Rehabilitation and Recovery
- Renal cell carcinoma treatment
- Moyamoya disease diagnosis and treatment
- Coronary Interventions and Diagnostics
- Spinal Fractures and Fixation Techniques
- Cerebrospinal fluid and hydrocephalus
- Surgical Simulation and Training
- Species Distribution and Climate Change
- Pediatric Urology and Nephrology Studies
- Kruppel-like factors research
- Ecology and Vegetation Dynamics Studies
- Cardiovascular Health and Disease Prevention
- COVID-19 and healthcare impacts
- Peripheral Artery Disease Management
- Rangeland and Wildlife Management
Penn State Milton S. Hershey Medical Center
2016-2025
Pennsylvania State University
2013-2023
Apollo Hospitals
2021
Beth Israel Deaconess Medical Center
2019
Memorial Hermann
2016
United States Naval Hospital Okinawa
2016
University of California, Davis
2014
Virginia Commonwealth University
2011-2013
Charlottesville Medical Research
2012
University of Richmond
2012
The ivory-billed woodpecker ( Campephilus principalis ), long suspected to be extinct, has been rediscovered in the Big Woods region of eastern Arkansas. Visual encounters during 2004 and 2005, analysis a video clip from April 2004, confirm existence at least one male. Acoustic signatures consistent with display drums also have heard region. Extensive efforts find birds away primary encounter site remain unsuccessful, but potential habitat for thinly distributed source population is vast...
<h3>BACKGROUND AND PURPOSE:</h3> Preoperative embolization for intracranial meningiomas offers potential advantages safer and more effective surgery. However, this treatment strategy has not been examined in a large comparative series. The purpose of study was to review our experience using preoperative understand the efficacy, technical considerations complications technique. <h3>MATERIALS METHODS:</h3> We performed retrospective patients undergoing meningioma resection at institution...
We present the incidence of complications and conversions during laparoscopic nephrectomy performed for various indications discuss methods to help prevent future complications.From June 1999 February 2003 at our institution 285 cases were performed, consisting 113 radical nephrectomies, 101 donor 27 simple 23 partial nephrectomies 21 nephroureterectomies. reviewed data base patients who underwent examine analyze factors related conversion an open surgical procedure.Major occurred in 16...
A retrospective study was performed to determine the course of limb-length discrepancies occurring in patients with monoarticular and pauciarticular juvenile rheumatoid arthritis. Data were assessed on thirty-six followed skeletal maturity, fifteen who had not reached maturity but been for four years or more, forty-nine three less. In seventy-two total 100 onset disease occurred before they five old, ninety involvement knee. All whom developed age nine overgrowth involved extremity, that...
Coronary artery disease (CAD) is characterised by progressive atherosclerotic plaque leading to flow-limiting stenosis, while myocardial infarction (MI) occurs due rupture or erosion with abrupt coronary occlusion. Multiple inflammatory pathways influence stability, but direct assessment of endothelial inflammation at the site stenosis has largely been limited pathology samples animal models atherosclerosis. We describe a technique for isolating and characterising cells (ECs) EC...
INTRODUCTION: Intracerebral hemorrhage (ICH) is a devastating disease with 30-day mortality rate greater than 40%. Following hemorrhage, iron released from blood-breakdown leads to an iron-dependent form of cell-death known as ferroptosis. Animal studies on genetic variations in metabolism demonstrate that the H67D HFE mutation reduces ICH-associated However, impact commonly found human homolog, H63D mutation, has not been studied stroke patients. METHODS: Four different machine learning...
Nephron sparing surgery is an accepted treatment for small renal masses, of which many have been detected incidentally due to the widespread use advanced imaging techniques. We report our experience with laparoscopic nephron surgery.From May 2000 2002 a total 20 partial nephrectomies were performed in 19 patients. The kidney was mobilized allow adequate dissection, hemostasis and inspection kidney. Cautery, harmonic scalpel TissueLink (TissueLink Medical, Inc., Dover, New Hampshire) device...
Acute ischemic stroke (AIS) is a leading cause of mortality that occurs when an embolus becomes lodged in the cerebral vasculature and obstructs blood flow brain. The severity AIS determined by location how extensively emboli become lodged, which are dictated large part dynamics migration difficult to measure vivo patients. Computational fluid (CFD) can be used predict patient-specific hemodynamics lodging better understand underlying mechanics AIS. To relied upon, however, computational...
OBJECTIVE Onyx HD-500 is a liquid embolic agent consisting of ethylene vinyl alcohol copolymer dissolved in dimethylsulfoxide and mixed with tantalum. This viscous was designed to treat intracranial side wall aneurysms, but there have been no prospective published series from the United States. From this early experience, we developed several protocol revisions, technical details, clinical pearls that not for embolization aneurysms. CLINICAL PRESENTATION We present our single-center patients...
Background and purpose Current technology for endovascular thrombectomy in ischemic stroke utilizes static loading is successful approximately 85% of cases. Existing uses either suction (applied via a continuous pump or syringe) flow arrest with proximal balloon. In this paper we evaluate the potential cyclic aspiration thrombectomy. Methods order to efficacy aspiration, model was created using Penumbra system, three-way valve 5Max catheter. Synthetic clots were aspirated at different...
Abstract BACKGROUND Prior comparisons of brain arteriovenous malformations (AVMs) treated using stereotactic radiosurgery (SRS) with or without embolization were inherently flawed, due to differences in the pretreatment nidus volumes. OBJECTIVE To compare outcomes and SRS, vs SRS alone for AVMs pre-embolization malformation features. METHODS We retrospectively reviewed International Radiosurgery Research Foundation AVM databases from 1987 2018. Patients categorized into (E + SRS) (SRS-only)...
Embolization of intracranial arteriovenous malformations (AVMs) is generally a preoperative adjunctive procedure in the USA. However, sometimes embolization can result complete angiographic obliteration AVM. There significant controversy regarding best management strategy for this subset patients. scarcity literature predicting which embolized, angiographically obliterated AVMs are likely to recur and ones cured. We present our series patients with their from embolization.A prospectively...
Background: Trigeminal neuralgia (TN) is a syndrome with debilitating paroxysmal facial pain, one cause of which thought to be vascular compression the nerve root entry zone causing ephaptic transmission. Arteriovenous malformations (AVM) have been reported TN, including AVMs in cerebellopontine (CP) angle. These lesions successfully treated endovascular coiling, ethylene-vinyl alcohol copolymer (Onyx) and surgery for decompression.
Postprocedural rebleeding is a significant source of morbidity following endovascular treatment ruptured intracranial aneurysms. Previous large-scale reports include the Cerebral Aneurysm Rerupture After Treatment trial, International Subarachnoid Trial, and study on Early Rebleeding after Coiling Ruptured Aneurysms, which reported nonprocedural rates within 30 days 2.7%, 1.9%, 1.4%, respectively. However, coiling aneurysms in state continual change due to advancing device design evolving...
Background The Penumbra system uses a coaxial separator and continuous extracorporeal suction to remove clot from cerebral artery. Forced-suction thrombectomy (FST) involves aspirating clots through the same reperfusion catheter using only syringe, decreasing procedure time supplies needed. Objective To evaluate multiple combinations of catheters syringes determine optimal pairing for use in FST. Methods Tests were performed both aspirate water 0.041 inch (041), 4Max, 0.054 (054) 5Max...
OBJECTIVE Investigations of the combined effects neoadjuvant Onyx embolization and stereotactic radiosurgery (SRS) on brain arteriovenous malformations (AVMs) have not accounted for initial angioarchitectural features prior to neuroendovascular intervention. The aim this retrospective, multicenter matched cohort study is compare outcomes SRS with versus without upfront AVMs using de novo characteristics preembolized nidus. METHODS International Radiosurgery Research Foundation AVM databases...
Introduction Embolization of wide-necked intracranial aneurysms can be associated with excessive expense, especially for large/giant aneurysms. Depending on the material used, endovascular treatment may cost prohibitive. The goal this study was to evaluate relative various embolic agents. Methods Utilizing software available at http://www.angiocalc.com , theoretical aneurysm volumes were calculated using diameters ranging from 3 25 mm increasing in 1 increments. For each volume, length coil...
One of the most challenging aspects laparoscopic partial nephrectomy is achieving adequate control bleeding from tumor bed. We report our initial experience with nephron-sparing surgery using TissueLink floating-ball radiofrequency dissector.From March 2002 to April 2003, we performed 14 purely nephrectomies device on 11 patients.The mean operative time was 124 minutes (range 90-210 minutes). The estimated blood loss 168 mL 20-600 mL). patient had a small urine leak and sent home drain in...