A5004097738- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- COVID-19 Clinical Research Studies
- Eosinophilic Disorders and Syndromes
- Blood groups and transfusion
- Acute Lymphoblastic Leukemia research
- CNS Lymphoma Diagnosis and Treatment
- Platelet Disorders and Treatments
- Kruppel-like factors research
- Viral-associated cancers and disorders
- Retinoids in leukemia and cellular processes
- Cancer Treatment and Pharmacology
- COVID-19 and healthcare impacts
- Autoimmune and Inflammatory Disorders Research
- Protein Degradation and Inhibitors
- Bone and Joint Diseases
- Hemoglobinopathies and Related Disorders
- Inflammatory Biomarkers in Disease Prognosis
- Polyomavirus and related diseases
- Hematological disorders and diagnostics
- Histiocytic Disorders and Treatments
Istanbul Medipol University
2023-2025
Sağlık Bilimleri Üniversitesi
2017-2024
Universidad CES
2021-2024
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2018-2022
Alanya Hamdullah Emin Pasa University
2022
Alanya Alaaddin Keykubat Üniversitesi
2022
University of Health Science
2021-2022
University of Health Sciences
2021
University of Health Sciences Antigua
2021
Adli Tıp Kurumu
2020
Chronic myeloproliferative disorders such as polycythemia vera (PV), essential thrombocytosis (ET), and idiopathic myelofibrosis arise from clonal proliferation of neoplastic stem cells in the bone marrow. Matrix metalloproteinases (MMPs) are a family zinc-dependent endopeptidases that have potential to degrade all types extracellular matrix (ECM) also play role remodeling ECM. It is known MMPs marrow remodeling.The primary goal our study explore relationship between chronic diseases some...
All-trans retinoic acid (ATRA) is a physiological metabolite of vitamin A and it used for the treatment acute promyelocytic leukemia (APL). Hypercalcemia rare side effect ATRA may be potentiated after interaction with azole group antifungals. Herein, we have reported an APL case hypercalcemia that caused by posaconazole.A 49-year-old female patient was diagnosed as examinations performed upon detection pancytopenia when she had presented complaints widespread bruising fever. After initiation...
Patients with solid malignancies are more vulnerable to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection than the healthy population. The outcome of SARS-CoV-2 in highly immunosuppressed populations, such as patients hematological malignancies, is a point interest. We aimed analyze symptoms, complications, intensive care unit admissions, and mortality rates infected Turkey.In this multicenter study, we included 340 adult pediatric diagnosed from March November 2020....
In this study, we aimed to obtain real-life data on the use of antimyeloma agents, which significantly increase overall survival (OS) in multiple myeloma (MM) patients, primary plasma cell leukemia (pPCL) patients with a poor prognosis.
Central nervous system (CNS) involvement in multiple myeloma (MM) is a rare and challenging complication associated with poor prognosis limited treatment options. Emerging T-cell directing therapies, such as bispecific antibodies (bsAbs) chimeric antigen receptor T cells (CAR-T), have shown remarkable success treating MM, but their efficacy CNS remains unclear. Elranatamab, humanized antibody targeting B-cell maturation (BCMA) CD3-expressing cells, has demonstrated promising results relapsed...
Immunophenotyping has a central role in CLL. However, CLL is very heterogenous disease, both morphologically and immunophenotypically; thus, its diagnosis may prove challenge. We investigated CD81 ex-pression the differential of MCL.We retrospectively examined expression with 8 color Multiparameter Flow cytometry devices 101 19 MCL cases.We found negative cases whereas it was positive cases.Our results suggest that be valuable marker for are opinion should definitely included diagnostic algorithm
Introduction Dasatinib is a potent tyrosine-kinase inhibitor which used for chronic myeloid leukemia treatment. Pleural effusion frequent side effect in patients during dasatinib Pulmonary arterial hypertension rare and life-threatening adverse event of dasatinib. The relationship between autoimmune disorders unclear, but there are reports possible mechanisms that have triggered autoimmunity by Case report A 53-year-old male was diagnosed with initiated imatinib mesylate as Imatinib changed...
Introduction Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life-threatening syndrome of excessive immune activation. Herein, we aimed to report a diffuse large B-cell lymphoma (DLBCL) case that was presented as HLH. Case A 32-year-old man hospital with complaints vomiting, nausea diarrhea in October 2019. Fever hepatosplenomegaly detected physical investigation. Bone marrow aspiration investigation revealed the hemaphagocytosis. HLH-2004 protocol started for hemophagocytosis....
Bacterial infections and febrile neutropenia (FN) are major causes of morbidity mortality in patients with hematological malignancy. The aim this study was to investigate the incidence risk factors lymphoma patients.This retrospective conducted on 200 diagnosed treated between January 2009 December 2017 Diskapi Yildirim Beyazit Training Research Hospital, a tertiary referral hospital Ankara, Turkey.The mean follow-up period 20.09 ± 19.81 months. infection episode (IE) 32.5% (65/200) FN 18.5%...
Patients with cancer are at increased risk of thromboembolic complications. There is no evidence-based guideline on the use routine prophylaxis in hematological malignancies except patients multiple myeloma. The purpose this study was to determine incidence and factors thrombosis suggest a rationale for primary thromboprophylaxis acute leukemia lymphoma patients.A retrospective conducted newly-diagnosed who presented our institution from November 2009 March 2018. included total 157 238...
Amaç: Anjiyofolliküler lenf nodu hiperplazisi olarak da bilinen Castleman hastalığı (CH), nadir bir hastalık olup başlıca hiyalin vasküler ve plazma hücreli olmak üzere 2 histolojik alt tipi vardır.Hastalığın anatomik yayılımı tutulan bölgelerinin sayısına göre unisentrik (UCH) ya multisentrik (MCH) sınıflandırılır.Bu çok merkezli çalışmanın amacı bugüne kadar Türkiye'de tanımlanan tüm CH olgularını tanımlamak, ulusal veri tabanı oluşturarak CH'de erken tanı, tedavi takip sürecine katkı
Acquired hemophilia A (AHA) which presents with spontaneous severe intramuscular, mucosal and/or subcutaneous bleeding is a rare disorder. Even 50% of AHA patients are defined as idiopathic; 10% cases related malignancy. Here, we present case in 43-year-old lady who was diagnosed malignancy and venous thromboembolism on vena cava 2 years ago. To the best our knowledge, this first report literature presented both acquired thrombosis associated routine workup for like solid tumors,...