Jinxin Xie

ORCID: 0000-0003-4772-7162
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About
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Research Areas
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • Herpesvirus Infections and Treatments
  • Vector-Borne Animal Diseases
  • Cervical Cancer and HPV Research
  • Plant Virus Research Studies
  • Animal Disease Management and Epidemiology
  • Virus-based gene therapy research
  • T-cell and Retrovirus Studies
  • Viral Infections and Immunology Research
  • Escherichia coli research studies
  • Parvovirus B19 Infection Studies
  • Respiratory viral infections research
  • Cytomegalovirus and herpesvirus research
  • Hepatitis Viruses Studies and Epidemiology
  • Antibiotic Resistance in Bacteria
  • Polysaccharides and Plant Cell Walls
  • Bacterial Genetics and Biotechnology
  • Regional Development and Environment
  • Poxvirus research and outbreaks
  • Toxoplasma gondii Research Studies
  • Ginseng Biological Effects and Applications
  • Efficiency Analysis Using DEA
  • Energy, Environment, Economic Growth
  • Liver Diseases and Immunity

Xinjiang Agricultural University
2019-2025

Jilin University
2015-2024

Xinjiang Entry-Exit Inspection and Quarantine Bureau
2024

Chinese Academy of Agricultural Sciences
2024

Jilin Medical University
2024

China Animal Disease Control Center
2024

South China Agricultural University
2024

Hunan Police Academy
2024

National Institutes for Food and Drug Control
2024

Peking University
2021

Lumpy skin disease (LSD) is a viral of cattle caused by LSD virus (LSDV). This poses significant threat to stockbreeding and listed as one bovine notifiable diseases OIE. Before 2019, has not been reported in China. The first outbreak was determined China on August 3, 2019. Since then, total 7 outbreaks have other 6 provinces China, infecting 91 killing cattle. As now, LSDV detected western eastern also Taiwan Island outside Mainland undoubtedly an emerging the industry

10.1111/tbed.13898 article EN Transboundary and Emerging Diseases 2020-10-29

Bats are considered important animal reservoirs for many viruses pathogenic to humans. An approach based on viral metagenomics was used study gut specimens from 78 insectivorous bats in Yunnan Province, China. Seventy-four reads were found be related group A rotavirus (RVA). Further reverse transcription-PCR screening and isolation cell cultures confirmed the presence of a novel RVA strain, named RVA/Bat-tc/MSLH14/2012/G3P[3], 1 (6%) 16 lesser horseshoe bats. Full genomic sequencing analyses...

10.1128/jvi.02013-13 article EN Journal of Virology 2013-09-12

This investigation aimed to examine the virulence genes and antimicrobial resistance profiles of Shiga toxin-producing

10.1089/fpd.2024.0056 article EN Foodborne Pathogens and Disease 2025-01-06

Abstract Background Equine herpesvirus type 1 (EHV-1) is commonly associated with horse abortion. Currently, there are no reported cases of abortion resulting from EHV-1 infection in donkeys. Results This was the first survey-based study Chinese The presence identified by PCR. survey conducted Chabuchar County, North Xinjiang, China, 2020. A donkey strain (Chabuchar/2020) successfully isolated MDBK cells. Seventy-two 100 sera were able to neutralize EHV-1. Moreover, ORF33 sequence...

10.1186/s12985-024-02390-2 article EN cc-by Virology Journal 2024-05-27

Ligands are an imperative part of targeted drug delivery systems, and choosing a ligand with high affinity is subject considerable interest. In this study, we first synthesized 12-residue peptide (TK) that interacts integrin α6β1 overexpressed on colonic cancer cells. The molecular binding assay indicated TK had for α6β1. results cellular tumor spheroid uptake suggested not only increases Caco-2 cells uptake, but also effectively penetration the spheroids. TK-conjugated PEG-PLA was to...

10.3109/10717544.2015.1077293 article EN Drug Delivery 2015-08-14

EHV-1 is one of the most serious viral pathogens that frequently cause abortion in horses around world. However, so far, relatively little information available on infections as they occur China. In January 2021, during an storm which occurred Yili at Chinese State Studs Zhaosu (North Xinjiang, China), 43 out 800 pregnant mares aborted.PCR detection revealed presence all samples possible abortions, although EHV-4, EHV-2 and EHV-5 were also found to circulate aborted fetuses. Furthermore,...

10.1186/s12917-022-03171-1 article EN cc-by BMC Veterinary Research 2022-03-01

Varicellovirus equidalpha1 (formerly Equid alphaherpesvirus 1, EqAHV-1) is among the most important viruses responsible for respiratory disease outbreaks horses throughout world. No reports to date have detailed association between EqAHV-1 and in China. This study described one such outbreak a population of north Xinjiang that occurred from April 2021 - May 2023.

10.1186/s12917-024-03925-z article EN cc-by BMC Veterinary Research 2024-02-27

Porcine reproductive and respiratory syndrome virus (PRRSV), a member of the Arteriviridae family, represents persistent menace to global pig industry, causing failure disease in pigs. In this study, we delved into role histone deacetylases (HDAC2) during PRRSV infection. Our findings revealed that HDAC2 expression is downregulated upon Notably, suppressing activity through specific small interfering RNA led an increase production, whereas overexpressing effectively inhibited replication by...

10.3390/v16050678 article EN cc-by Viruses 2024-04-25

In 2015, a novel equine parvovirus, parvovirus-cerebrospinal fluid (EqPV-CSF), was identified from cerebrospinal of horse with neurological signs and lymphocytosis in USA. our study, an EqPV-CSF-like virus detected 15 serum samples 65 imported thoroughbred horses during custom quarantine north Xinjiang province, China. Further field investigation several major horse-producing areas using specific PCR showed that this mainly (39/154 positive) previously imported, not local breeds (0/127...

10.1111/tbed.13443 article EN Transboundary and Emerging Diseases 2019-12-03

The bovine Escherichia coli O157:H7 is a major foodborne pathogen causing severe bloody diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome in humans. Cattle are recognized reservoir source of E. O157:H7. We investigated the antibiotic resistance, molecular profiles, intrinsic relationship between 21 isolates from cattle farms slaughtering houses Xinjiang. Using pulsed-field gel electrophoresis (PFGE) typing, two types PFGE were revealed through cluster analysis, including clusters...

10.3389/fvets.2021.574801 article EN cc-by Frontiers in Veterinary Science 2021-05-25

Non-O157 Shiga toxin (stx)-producing Escherichia coli (STEC) is recognized as an important human diarrheal pathogen. Cattle are the principal reservoirs of STEC, although other animals can be carriers. Humans mainly infected by consuming contaminated drinking water or food. This study aimed to evaluate virulence potential isolated bovine non-O157 STEC humans in Xinjiang. During 2015-2017, 978 rectal swab samples collected from cattle 5 farms were screened for presence toxin-encoding genes...

10.1089/fpd.2021.0020 article EN Foodborne Pathogens and Disease 2021-08-20

Abstract Kirkovirus (kirV), a seemingly novel virus family, has been found in horses and donkeys. The objectives of the study intend to investigate presence swine. In this study, donkey-like kirV was detected rectal swabs piglets with diarrhea, positive rate be 100% (149/149), however only one 261 clinically healthy piglets, which suggested strong relationship between diarrheic disease. We obtained whole-genome sequences three kirVs (named Cj-D5, Cj-D32 Cj-D43), length 3750 nt sharing 99.9%...

10.21203/rs.3.rs-3878549/v1 preprint EN cc-by Research Square (Research Square) 2024-01-26

In this study, a novel kirkovirus (kirV) was detected in anal swabs of piglets with diarrhoea, the positive rate 100% (149/149), but virus one 261 clinically healthy piglets, result suggests strong relationship between kirV and diarrhoeal disease. We obtained whole-genome sequences three kirVs (named Cj-D5, Cj-D32 Cj-D43), length 3750 nt, shared 86.6%–89.0% nt-identity equine Equ1 Cj-7-7. Furthermore, viruses share32.1%–93.4%, 22.2%–27.1% Rep protein sequence identity available reference...

10.22541/au.170664427.74237523/v1 preprint EN Authorea (Authorea) 2024-01-30

Abstract Background: Varicellovirus equidalpha1 (formerly Equid alphaherpesvirus 1, EqAHV-1) is commonly linked to horse abortion. Currently, there are no reported cases of abortion resulting from EqAHV-1 infection in donkeys. Case presentation: This was the first survey-based study Chinese donkeys, which identified three aborted fetal lung tissues donkeys via PCR technique. survey conducted Chabuchar County, north Xinjiang, China, 2020. A donkey strain (Chabuchar/2020) successfully isolated...

10.21203/rs.3.rs-3948282/v1 preprint EN cc-by Research Square (Research Square) 2024-02-16

Abstract Introduction Viruses are among the main pathogens causing diarrhoea in calves. The current study found that bovine norovirus (BNoV) is one of principal viruses calves Xinjiang, China. Material and Methods A total 974 calf faecal samples from six regions Xinjiang were tested for BNoV using reverse-transcriptase PCR. genomic characteristics genetic evolution VP1 gene, protein three-dimensional structure amino acid variation analysed bioinformatics methods. Results Epidemiological...

10.2478/jvetres-2024-0005 article EN cc-by-nc-nd Journal of Veterinary Research 2024-02-19
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