Melanocyte stem cells (McSCs) and mouse models of hair graying serve as useful systems to uncover mechanisms involved in cell self-renewal the maintenance regenerating tissues. Interested assessing genetic variants that influence McSC maintenance, we found previously heterozygosity for melanogenesis associated transcription factor, Mitf, exacerbates differentiation mice are predisposed this phenotype. Based on transcriptome molecular analyses Mitfmi-vga9/+ mice, report a novel role MITF...

Journal Article ISOLATION OF HISTOPLASMA CAPSULATUM FROM ARIZONA BATS Get access ARTHUR F. DI SALVO, SALVO S. Carolina State Board of HealthColumbia, C. 29201 Search for other works by this author on: Oxford Academic PubMed Google Scholar LIBERO AJELLO, AJELLO JOSEPH W. PALMER, JR., JR. G. WINKLER American Epidemiology, Volume 89, Issue 5, May 1969, Pages 606–614, https://doi.org/10.1093/oxfordjournals.aje.a120973 Published: 01 1969 history Received: 05 August 1968

Journal Article SURVEY OF SOILS FOR HUMAN PATHOGENIC FUNGI FROM THE EMILIA-ROMAGNA REGION ITALY: II. ISOLATION ALLESCHERIA BOYDII, CRYPTOCOCCUS NEOFORMANS AND HISTOPLASMA CAPSULATUM Get access GIULIO SOTGIU, SOTGIU 1Istituto di Clinica Medica Generale e Terapia Medica, Università BolognaBologna, Italia Search for other works by this author on: Oxford Academic PubMed Google Scholar ALDO MAZZONI, MAZZONI ADRIANO MANTOVANI, MANTOVANI Guest Researcher 2Communicable Disease Center, Istituto...

a college student contracted histoplasmosis after exploring cave on biology field trip in the vicinity of Gainesville, Fla. (1).The cave, which infection apparently occurred, was inhabited by bats and con- tained abundant amounts guano.Since au- tochthonous is rare Florida, this case inspired search for source victim's infection.The investigation subse- quently expanded, guano-enriched soil that had been collected from all bat caves known to us State Florida were ana- lyzed systematically...

About 6 years ago, semitoric systems were classified by Pelayo & Vũ Ngọc means of five invariants. Standard examples are the coupled spin oscillator on $\mathbb{S}^2 \times \mathbb{R}^2$ and angular momenta \mathbb{S}^2$, both having exactly one focus-focus singularity. But so far there no explicit with more than singularity which in sense that classification. This paper introduces a $6$-parameter family integrable \mathbb{S}^2$ proves that, for certain ranges parameters, it is compact...

Abstract Melanocyte stem cells (McSCs) of the hair follicle are a rare cell population within skin and notably underrepresented in whole‐skin, single‐cell RNA sequencing (scRNA‐seq) datasets. Using enrichment strategy to isolate KIT+/CD45− from telogen adult female C57BL/6J mice, we evaluated transcriptional landscape quiescent McSCs (qMcSCs) at high resolution. Through this evaluation, confirmed existing molecular signatures for qMcCS subpopulations (e.g., Kit+ , Cd34+/− Plp1+ Cd274+/−...

SummaryInvestigation of a bat colony situated in the attic university building Alabama led to recovery Histoplasma capsulatum from 13 77 Florida free-tailed bats (Tadarida cynocephala). This fungus was also isolated two 42 samples guano collected study site.Soaking deposits and dust with 3% formalin recommended reduce hazard acquiring histoplasmosis by workmen others during renovation bat-infested building.The role played epidemiology is discussed.

The existence of an area in Europe which histoplasmosis is endemic was revealed by the isolation Histoplasma capsulatum from soil. soil specimen collected a chicken yard on farm near Bologna, Italy. Emilia-Romagna region had been selected for study because several, apparently autochthonous, human cases originated there.

Gray hair is a visible sign of tissue degeneration during aging. Graying attributed to dysfunction melanocyte stem cells (McSCs) that results in depletion their melanin-producing progeny. This non-lethal phenotype makes the follicle and its pigment system an attractive model for investigating mechanisms contribute aging therapeutic strategies combat this process. One potential combination RT1640, which comprised two drugs are known stimulate growth (cyclosporine A [CsA] minoxidil), along...

The aim of this paper is to give new insights about families integrable systems lifting a Hamiltonian $S^1$-space. Specifically, we study one-parameter $(M^4,\omega,F_t=(J,H_t))_{0 \leq t 1}$ with fixed $S^1$-space $(M,\omega,J)$ and which are semitoric for certain values the parameter $t$, focus on such in one singular point undergoes Hamiltonian-Hopf bifurcation (also called nodal trade context systems, more generally almost toric fibrations). Beyond also containing hypersemitoric...

Potentially masculine gonads of Aedes stimulans (Diptera: Culicidae) can be induced to become ovaries by exposing larvae elevated temperatures. A juvenile gonad when transplanted into another larva will a testis or an ovary in response stimuli which are wholly intrinsic the implanted gonad. Humoral factors hemocoel larval host do not influence direction morphogenesis organ.

Age-related hair graying is caused by malfunction in the regenerative potential of adult pigmentation system. The retention color over life an organism dependent on ability melanocyte stem cells and their progeny to produce pigment each time a new grows. variable association with genetic background suggesting that quantitative trait loci influencing this can be identified. Identification these may lead discovery novel interesting genes involved cell biology and/or melanogenesis. With mind we...

Poultry eggs are a low-cost, high-protein nutrient package that can be consumed as part of quality diets. However, consumption poultry egg products is historically contentious, which highlights the importance investigating impacts long-term on metabolic health. Our study utilized zebrafish, Danio rerio, newly defined model human health, to understand consequence consuming in lieu other well-described protein sources. Reference diets were formulated contain multisource with casein and fish...

Summary A central aspect of life-long stem cell function in slow cycling cells is the proper regulation cellular quiescence. How quiescent state achieved, whether all are equivalent, and if pool changes with age questions that remain unanswered. Using melanocyte (qMcSC) as a model, we found quiescence neither singular nor static process can be heterogeneous. As one example this heterogeneity, show portion qMcSCs expresses immune checkpoint protein PD-L1 at membrane (PD-L1 mem+ ), better...

Semitoric systems are a type of four-dimensional integrable system for which one the integrals generates global $S^1$-action; these were classified by Pelayo and Vu Ngoc in terms five symplectic invariants. We introduce study semitoric families, one-parameter families with fixed $S^1$-action that all but finitely many values parameter, goal developing strategy to find associated given partial list also enumerate possible behaviors such at parameter they not semitoric, providing examples...

The existence of an area in Europe which histoplasmosis is endemic was revealed by the isolation Histoplasma capsulatum from soil. soil specimen collected a chicken yard on farm near Bologna, Italy. Emilia-Romagna region had been selected for study because several, apparently autochthonous, human cases originated there.

Abstract Background Effective use of Danio rerio as a preclinical model requires standardization macronutrient sources to achieve scientific reproducibility across studies and labs. Our objective was evaluate single cell protein (SCP) for production open-source standardized diets with defined heath characteristics the zebrafish research community. We completed 16-week feeding trial using juvenile D. 31 days post-fertilization (dpf) (10 tanks per diet, 14 tank) formulated containing either...

Semitoric integrable systems were symplectically classified by Pelayo and Vu Ngoc in 2009-2011 terms of five invariants. Four these invariants already well-understood prior to the classification, but fifth invariant, so-called twisting index came as a surprise. Intuitively, encodes how structure neighborhood focus-focus fiber compares large-scale semitoric system it was originally defined comparing certain momentum maps. In first half present paper, we produce several new formulations which...

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Melanocyte stem cells (McSCs) of the hair follicle are a rare cell population within skin and notably underrepresented in whole-skin, single-cell RNA sequencing (scRNA-seq) datasets. Using enrichment strategy to isolate KIT+/CD45-cells from telogen adult female C57BL/6J mice, we evaluated transcriptional landscape quiescent McSCs (qMcSCs) at high resolution. Through this evaluation, confirmed existing molecular signatures for qMcCS subpopulations (e.g.,